increased circulating interleukin-17 level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the amount in the blood of a proinflammatory cytokine produced primarily by T-cells or their precursors (Mammalian Phenotype Ontology, MP_0008614)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008614
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Genes

10 gene mutations causing the increased circulating interleukin-17 level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL2 interleukin 2
IL22 interleukin 22
LYN LYN proto-oncogene, Src family tyrosine kinase
NCKAP1L NCK-associated protein 1-like
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PLCD1 phospholipase C, delta 1
PTPN6 protein tyrosine phosphatase, non-receptor type 6