increased circulating interleukin-13 level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the amount in the blood of a cytokine synthesized by T-cells that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B-cells, and appears to play a role in regulating inflammatory and immune responses (Mammalian Phenotype Ontology, MP_0008608)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008608
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Genes

2 gene mutations causing the increased circulating interleukin-13 level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
IRF1 interferon regulatory factor 1
NLRP3 NLR family, pyrin domain containing 3