increased circulating interferon-gamma level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the amount in the blood of the major interferon produced by mitogenically or antigenically stimulated lymphocytes that is involved in immunoregulation (Mammalian Phenotype Ontology, MP_0008577)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008577
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Genes

37 gene mutations causing the increased circulating interferon-gamma level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CAV1 caveolin 1, caveolae protein, 22kDa
CCL13 chemokine (C-C motif) ligand 13
CD44 CD44 molecule (Indian blood group)
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DUSP1 dual specificity phosphatase 1
FOXP3 forkhead box P3
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GPR183 G protein-coupled receptor 183
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL27RA interleukin 27 receptor, alpha
IRF1 interferon regulatory factor 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LYN LYN proto-oncogene, Src family tyrosine kinase
MAVS mitochondrial antiviral signaling protein
MMP9 matrix metallopeptidase 9
MST1R macrophage stimulating 1 receptor
MTA2 metastasis associated 1 family, member 2
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NFIL3 nuclear factor, interleukin 3 regulated
NOD2 nucleotide-binding oligomerization domain containing 2
PCSK1 proprotein convertase subtilisin/kexin type 1
PILRB paired immunoglobin-like type 2 receptor beta
PRF1 perforin 1 (pore forming protein)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAB27A RAB27A, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RHBDD3 rhomboid domain containing 3
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SIRT3 sirtuin 3
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STX11 syntaxin 11
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TP53 tumor protein p53
VAV1 vav 1 guanine nucleotide exchange factor