increased circulating interferon-alpha level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the amount in the blood of one of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells that has antiviral activity and activates natural killer cells and B cells (Mammalian Phenotype Ontology, MP_0008573)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008573
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Genes

4 gene mutations causing the increased circulating interferon-alpha level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAR adenosine deaminase, RNA-specific
GPR183 G protein-coupled receptor 183
PRF1 perforin 1 (pore forming protein)
USP21 ubiquitin specific peptidase 21