increased cell death Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increased occurrence of the cessation of function at the cellular level (Mammalian Phenotype Ontology, MP_0012556)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0012556
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Genes

508 gene mutations causing the increased cell death phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ACVR1 activin A receptor, type I
ADAR adenosine deaminase, RNA-specific
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADM adrenomedullin
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALMS1 Alstrom syndrome protein 1
AMER1 APC membrane recruitment protein 1
AMN amnion associated transmembrane protein
ANTXR2 anthrax toxin receptor 2
APAF1 apoptotic peptidase activating factor 1
APC adenomatous polyposis coli
APC2 adenomatosis polyposis coli 2
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARHGAP1 Rho GTPase activating protein 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ASTN1 astrotactin 1
ASXL1 additional sex combs like transcriptional regulator 1
ATF4 activating transcription factor 4
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATR ATR serine/threonine kinase
AURKB aurora kinase B
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAG3 BCL2-associated athanogene 3
BAG6 BCL2-associated athanogene 6
BBS1 Bardet-Biedl syndrome 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BIRC6 baculoviral IAP repeat containing 6
BLNK B-cell linker
BMP4 bone morphogenetic protein 4
BMPR1A bone morphogenetic protein receptor, type IA
BMPR1B bone morphogenetic protein receptor, type IB
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRD1 bromodomain containing 1
BRD2 bromodomain containing 2
BSX brain-specific homeobox
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C1QA complement component 1, q subcomponent, A chain
CACFD1 calcium channel flower domain containing 1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALCRL calcitonin receptor-like
CALR calreticulin
CAPRIN1 cell cycle associated protein 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAST calpastatin
CBFB core-binding factor, beta subunit
CBS cystathionine-beta-synthase
CCBE1 collagen and calcium binding EGF domains 1
CCDC47 coiled-coil domain containing 47
CCNI cyclin I
CCR2 chemokine (C-C motif) receptor 2
CD200 CD200 molecule
CD22 CD22 molecule
CD27 CD27 molecule
CD28 CD28 molecule
CD38 CD38 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDCA8 cell division cycle associated 8
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK11A cyclin-dependent kinase 11A
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK6 cyclin-dependent kinase 6
CDK7 cyclin-dependent kinase 7
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDX2 caudal type homeobox 2
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CENPJ centromere protein J
CERS1 ceramide synthase 1
CFLAR CASP8 and FADD-like apoptosis regulator
CHD7 chromodomain helicase DNA binding protein 7
CHD8 chromodomain helicase DNA binding protein 8
CHEK1 checkpoint kinase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CIT citron rho-interacting serine/threonine kinase
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit
CNR1 cannabinoid receptor 1 (brain)
COL8A2 collagen, type VIII, alpha 2
COPS5 COP9 signalosome subunit 5
COPS6 COP9 signalosome subunit 6
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
COQ9 coenzyme Q9
CORO1A coronin, actin binding protein, 1A
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRYAA crystallin, alpha A
CSRP2BP CSRP2 binding protein
CTCF CCCTC-binding factor (zinc finger protein)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBIP1 catenin, beta interacting protein 1
CUL1 cullin 1
CUL3 cullin 3
CUL4B cullin 4B
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DAD1 defender against cell death 1
DAXX death-domain associated protein
DCK deoxycytidine kinase
DCN decorin
DCTN1 dynactin 1
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DIDO1 death inducer-obliterator 1
DKC1 dyskeratosis congenita 1, dyskerin
DNM1L dynamin 1-like
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOT1L DOT1-like histone H3K79 methyltransferase
DRD2 dopamine receptor D2
DUSP1 dual specificity phosphatase 1
EDAR ectodysplasin A receptor
EHD4 EH-domain containing 4
ELAVL4 ELAV like neuron-specific RNA binding protein 4
EMX2 empty spiracles homeobox 2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPO erythropoietin
EPOR erythropoietin receptor
ERBB3 erb-b2 receptor tyrosine kinase 3
ERCC1 excision repair cross-complementation group 1
ERF Ets2 repressor factor
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV2 ets variant 2
EYA1 EYA transcriptional coactivator and phosphatase 1
FAIM Fas apoptotic inhibitory molecule
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FAT4 FAT atypical cadherin 4
FBLIM1 filamin binding LIM protein 1
FBXL5 F-box and leucine-rich repeat protein 5
FCMR Fc fragment of IgM receptor
FGF10 fibroblast growth factor 10
FGF2 fibroblast growth factor 2 (basic)
FGFRL1 fibroblast growth factor receptor-like 1
FKBP8 FK506 binding protein 8, 38kDa
FKTN fukutin
FNIP1 folliculin interacting protein 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXA1 forkhead box A1
FOXA2 forkhead box A2
FOXI1 forkhead box I1
FOXP3 forkhead box P3
FRAS1 Fraser extracellular matrix complex subunit 1
FSHR follicle stimulating hormone receptor
FXN frataxin
G2E3 G2/M-phase specific E3 ubiquitin protein ligase
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G6PD glucose-6-phosphate dehydrogenase
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GAL galanin/GMAP prepropeptide
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GBA2 glucosidase, beta (bile acid) 2
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GDF11 growth differentiation factor 11
GFRA3 GDNF family receptor alpha 3
GJC1 gap junction protein, gamma 1, 45kDa
GLIS2 GLIS family zinc finger 2
GLMN glomulin, FKBP associated protein
GLMP glycosylated lysosomal membrane protein
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GPX1 glutathione peroxidase 1
GPX7 glutathione peroxidase 7
GREM1 gremlin 1, DAN family BMP antagonist
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRN granulin
GSTM5 glutathione S-transferase mu 5
GSTZ1 glutathione S-transferase zeta 1
HAND2 heart and neural crest derivatives expressed 2
HAX1 HCLS1 associated protein X-1
HDAC2 histone deacetylase 2
HELLS helicase, lymphoid-specific
HEXB hexosaminidase B (beta polypeptide)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLTF helicase-like transcription factor
HMOX1 heme oxygenase 1
HNF4A hepatocyte nuclear factor 4, alpha
HPCA hippocalcin
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HTRA2 HtrA serine peptidase 2
HTT huntingtin
HUS1 HUS1 checkpoint homolog (S. pombe)
HYOU1 hypoxia up-regulated 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP1 insulin-like growth factor binding protein 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL10 interleukin 10
IL15RA interleukin 15 receptor, alpha
IL34 interleukin 34
IL6 interleukin 6
IL6R interleukin 6 receptor
ILF3 interleukin enhancer binding factor 3, 90kDa
ILK integrin-linked kinase
ING1 inhibitor of growth family, member 1
ING2 inhibitor of growth family, member 2
INPP5F inositol polyphosphate-5-phosphatase F
INSM1 insulinoma-associated 1
IQGAP2 IQ motif containing GTPase activating protein 2
ITGA1 integrin, alpha 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
IVNS1ABP influenza virus NS1A binding protein
JUN jun proto-oncogene
KAT2A K(lysine) acetyltransferase 2A
KAT7 K(lysine) acetyltransferase 7
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM1A lysine (K)-specific demethylase 1A
KDM2B lysine (K)-specific demethylase 2B
KIDINS220 kinase D-interacting substrate, 220kDa
KIF14 kinesin family member 14
KIF20B kinesin family member 20B
KIFAP3 kinesin-associated protein 3
KITLG KIT ligand
KLF10 Kruppel-like factor 10
KMT2B lysine (K)-specific methyltransferase 2B
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT17 keratin 17, type I
LAMA1 laminin, alpha 1
LAMA5 laminin, alpha 5
LBR lamin B receptor
LDLR low density lipoprotein receptor
LECT2 leukocyte cell-derived chemotaxin 2
LEMD3 LEM domain containing 3
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIG4 ligase IV, DNA, ATP-dependent
LIN7C lin-7 homolog C (C. elegans)
LRP2 low density lipoprotein receptor-related protein 2
LRRK2 leucine-rich repeat kinase 2
LYNX1 Ly6/neurotoxin 1
LZTS1 leucine zipper, putative tumor suppressor 1
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPKAP1 mitogen-activated protein kinase associated protein 1
MBOAT7 membrane bound O-acyltransferase domain containing 7
MCM10 minichromosome maintenance complex component 10
MCPH1 microcephalin 1
MDM4 MDM4, p53 regulator
MECP2 methyl CpG binding protein 2
MEIOB meiosis specific with OB domains
MERTK MER proto-oncogene, tyrosine kinase
MIS18A MIS18 kinetochore protein A
MKL1 megakaryoblastic leukemia (translocation) 1
MKS1 Meckel syndrome, type 1
MPG N-methylpurine-DNA glycosylase
MPI mannose phosphate isomerase
MSRB3 methionine sulfoxide reductase B3
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYD88 myeloid differentiation primary response 88
NABP2 nucleic acid binding protein 2
NBN nibrin
NCKAP1 NCK-associated protein 1
NCOA5 nuclear receptor coactivator 5
NCOA6 nuclear receptor coactivator 6
NCSTN nicastrin
NEUROD1 neuronal differentiation 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NFYA nuclear transcription factor Y, alpha
NHEJ1 nonhomologous end-joining factor 1
NOG noggin
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH2 notch 2
NOVA1 neuro-oncological ventral antigen 1
NPAS4 neuronal PAS domain protein 4
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRIP1 nuclear receptor interacting protein 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OGG1 8-oxoguanine DNA glycosylase
OSR1 odd-skipped related transciption factor 1
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARG poly (ADP-ribose) glycohydrolase
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PARL presenilin associated, rhomboid-like
PARP1 poly (ADP-ribose) polymerase 1
PARP14 poly (ADP-ribose) polymerase family, member 14
PAX2 paired box 2
PAX8 paired box 8
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCTP phosphatidylcholine transfer protein
PDCD1 programmed cell death 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PELI1 pellino E3 ubiquitin protein ligase 1
PEX11B peroxisomal biogenesis factor 11 beta
PINK1 PTEN induced putative kinase 1
PIP prolactin-induced protein
PITX3 paired-like homeodomain 3
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PKNOX1 PBX/knotted 1 homeobox 1
PKP3 plakophilin 3
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLP1 proteolipid protein 1
PNP purine nucleoside phosphorylase
PNPLA6 patatin-like phospholipase domain containing 6
POLB polymerase (DNA directed), beta
POLG polymerase (DNA directed), gamma
POR P450 (cytochrome) oxidoreductase
POU2AF1 POU class 2 associating factor 1
POU3F3 POU class 3 homeobox 3
PPARD peroxisome proliferator-activated receptor delta
PRICKLE1 prickle homolog 1 (Drosophila)
PRKCD protein kinase C, delta
PRKCQ protein kinase C, theta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRNP prion protein
PSEN1 presenilin 1
PSEN2 presenilin 2
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTPMT1 protein tyrosine phosphatase, mitochondrial 1
PTPRC protein tyrosine phosphatase, receptor type, C
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD51 RAD51 recombinase
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RB1 retinoblastoma 1
RB1CC1 RB1-inducible coiled-coil 1
RBBP6 retinoblastoma binding protein 6
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBL2 retinoblastoma-like 2
RBX1 ring-box 1, E3 ubiquitin protein ligase
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REST RE1-silencing transcription factor
RET ret proto-oncogene
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RGN regucalcin
RHEB Ras homolog enriched in brain
RLN1 relaxin 1
RNASEH1 ribonuclease H1
RNF7 ring finger protein 7
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RORC RAR-related orphan receptor C
RPL22 ribosomal protein L22
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS7 ribosomal protein S7
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RUNX1 runt-related transcription factor 1
S1PR1 sphingosine-1-phosphate receptor 1
SALL1 spalt-like transcription factor 1
SARM1 sterile alpha and TIR motif containing 1
SEC23B Sec23 homolog B (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEPN1 selenoprotein N, 1
SEPP1 selenoprotein P, plasma, 1
SEPT9 septin 9
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SESN2 sestrin 2
SFN stratifin
SH3BP2 SH3-domain binding protein 2
SHARPIN SHANK-associated RH domain interactor
SHH sonic hedgehog
SIRT7 sirtuin 7
SIX1 SIX homeobox 1
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMAD5 SMAD family member 5
SMAD7 SMAD family member 7
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOS1 son of sevenless homolog 1 (Drosophila)
SOX11 SRY (sex determining region Y)-box 11
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPINT1 serine peptidase inhibitor, Kunitz type 1
SRRT serrate, RNA effector molecule
SSBP3 single stranded DNA binding protein 3
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STIP1 stress-induced phosphoprotein 1
STK4 serine/threonine kinase 4
STK40 serine/threonine kinase 40
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUMF1 sulfatase modifying factor 1
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SYK spleen tyrosine kinase
SYNGAP1 synaptic Ras GTPase activating protein 1
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAL1 T-cell acute lymphocytic leukemia 1
TBX1 T-box 1
TBX4 T-box 4
TCAP titin-cap
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
TCOF1 Treacher Collins-Franceschetti syndrome 1
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TFAM transcription factor A, mitochondrial
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
TFRC transferrin receptor
THOC1 THO complex 1
TIGAR TP53 induced glycolysis regulatory phosphatase
TIMP3 TIMP metallopeptidase inhibitor 3
TJP2 tight junction protein 2
TLR2 toll-like receptor 2
TLX1 T-cell leukemia homeobox 1
TMEM8C transmembrane protein 8C
TNF tumor necrosis factor
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNIP1 TNFAIP3 interacting protein 1
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TP63 tumor protein p63
TP73 tumor protein p73
TPP2 tripeptidyl peptidase II
TPT1 tumor protein, translationally-controlled 1
TRAF2 TNF receptor-associated factor 2
TRAIP TRAF interacting protein
TRIM54 tripartite motif containing 54
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TTN titin
TUBB2B tubulin, beta 2B class IIb
TULP3 tubby like protein 3
TWSG1 twisted gastrulation BMP signaling modulator 1
TXN2 thioredoxin 2
UBD ubiquitin D
UBE4B ubiquitination factor E4B
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGCG UDP-glucose ceramide glucosyltransferase
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
USP10 ubiquitin specific peptidase 10
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP22 ubiquitin specific peptidase 22
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
VASN vasorin
VCL vinculin
VEGFA vascular endothelial growth factor A
VPRBP Vpr (HIV-1) binding protein
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WASH1 WAS protein family homolog 1
WT1 Wilms tumor 1
XBP1 X-box binding protein 1
XIRP2 xin actin binding repeat containing 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZBTB17 zinc finger and BTB domain containing 17
ZBTB18 zinc finger and BTB domain containing 18
ZDHHC13 zinc finger, DHHC-type containing 13
ZDHHC17 zinc finger, DHHC-type containing 17