increased brain size Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description larger than the normal physical proportions of the brain (Mammalian Phenotype Ontology, MP_0005238)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005238
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Genes

43 gene mutations causing the increased brain size phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADIPOR2 adiponectin receptor 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
APAF1 apoptotic peptidase activating factor 1
CASP9 caspase 9, apoptosis-related cysteine peptidase
CD81 CD81 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUX2 cut-like homeobox 2
CYCS cytochrome c, somatic
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
DDIT3 DNA-damage-inducible transcript 3
DLG5 discs, large homolog 5 (Drosophila)
GHR growth hormone receptor
GPR85 G protein-coupled receptor 85
IFT88 intraflagellar transport 88
IGF2R insulin-like growth factor 2 receptor
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KDM2B lysine (K)-specific demethylase 2B
KLF3 Kruppel-like factor 3 (basic)
MARK2 MAP/microtubule affinity-regulating kinase 2
MBD5 methyl-CpG binding domain protein 5
MECP2 methyl CpG binding protein 2
NBEA neurobeachin
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
OPHN1 oligophrenin 1
PAK1IP1 PAK1 interacting protein 1
PAPPA2 pappalysin 2
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PHF2 PHD finger protein 2
PTEN phosphatase and tensin homolog
PURA purine-rich element binding protein A
PYGO2 pygopus family PHD finger 2
SELENBP1 selenium binding protein 1
SIRT1 sirtuin 1
SIX3 SIX homeobox 3
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SPEF2 sperm flagellar 2
TMEM67 transmembrane protein 67
TP53 tumor protein p53
WWOX WW domain containing oxidoreductase