incomplete caudal neuropore closure Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description incomplete joining together of the neural folds of the caudal opening of the neural tube; failure of caudal neuropore closure results in spina bifida, the severity of which depends on how much of the spinal cord remains exposed (Mammalian Phenotype Ontology, MP_0012707)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0012707
Similar Terms
Downloads & Tools

Genes

9 gene mutations causing the incomplete caudal neuropore closure phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
CSK c-src tyrosine kinase
GRHL2 grainyhead-like 2 (Drosophila)
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MSGN1 mesogenin 1
PLXNB2 plexin B2
RAB23 RAB23, member RAS oncogene family
SP8 Sp8 transcription factor
TULP3 tubby like protein 3