inactivation Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

874 genes co-occuring with the biological term inactivation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACACA acetyl-CoA carboxylase alpha
ACE angiotensin I converting enzyme
ACVR2A activin A receptor, type IIA
ADAM17 ADAM metallopeptidase domain 17
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA3 adenosine A3 receptor
ADRB2 adrenoceptor beta 2, surface
AGO2 argonaute RISC catalytic component 2
AGTR1 angiotensin II receptor, type 1
AIM2 absent in melanoma 2
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
AJAP1 adherens junctions associated protein 1
AJUBA ajuba LIM protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
AMER1 APC membrane recruitment protein 1
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANGPTL4 angiopoietin-like 4
ANXA6 annexin A6
APAF1 apoptotic peptidase activating factor 1
APC adenomatous polyposis coli
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOC1 apolipoprotein C-I
APOC3 apolipoprotein C-III
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
AR androgen receptor
AREG amphiregulin
ARF1 ADP-ribosylation factor 1
ARF6 ADP-ribosylation factor 6
ARHGAP35 Rho GTPase activating protein 35
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARID1A AT rich interactive domain 1A (SWI-like)
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
ARMC5 armadillo repeat containing 5
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASCL2 achaete-scute family bHLH transcription factor 2
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ASIC1 acid sensing (proton gated) ion channel 1
ATF3 activating transcription factor 3
ATM ATM serine/threonine kinase
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATR ATR serine/threonine kinase
AURKB aurora kinase B
AXIN1 axin 1
AXL AXL receptor tyrosine kinase
B2M beta-2-microglobulin
BAAT bile acid CoA:amino acid N-acyltransferase
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BBS12 Bardet-Biedl syndrome 12
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCR breakpoint cluster region
BECN1 beclin 1, autophagy related
BEX1 brain expressed, X-linked 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BIN1 bridging integrator 1
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRAP BRCA1 associated protein
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRD4 bromodomain containing 4
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1
BRSK1 BR serine/threonine kinase 1
BRSK2 BR serine/threonine kinase 2
BSN bassoon presynaptic cytomatrix protein
BTG3 BTG family, member 3
BTG4 B-cell translocation gene 4
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C20ORF85 chromosome 20 open reading frame 85
C2ORF40 chromosome 2 open reading frame 40
C3 complement component 3
C5 complement component 5
CABLES1 Cdk5 and Abl enzyme substrate 1
CABP1 calcium binding protein 1
CABP4 calcium binding protein 4
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CADM1 cell adhesion molecule 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMP cathelicidin antimicrobial peptide
CAPN1 calpain 1, (mu/I) large subunit
CARD11 caspase recruitment domain family, member 11
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC6 coiled-coil domain containing 6
CCL14 chemokine (C-C motif) ligand 14
CCNB1 cyclin B1
CCND1 cyclin D1
CCNE1 cyclin E1
CD59 CD59 molecule, complement regulatory protein
CD80 CD80 molecule
CD82 CD82 molecule
CD86 CD86 molecule
CD9 CD9 molecule
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC25C cell division cycle 25C
CDC42 cell division cycle 42
CDC73 cell division cycle 73
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH13 cadherin 13
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDK6 cyclin-dependent kinase 6
CDK7 cyclin-dependent kinase 7
CDKL5 cyclin-dependent kinase-like 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDO1 cysteine dioxygenase type 1
CDON cell adhesion associated, oncogene regulated
CDX1 caudal type homeobox 1
CDX2 caudal type homeobox 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFH complement factor H
CFL1 cofilin 1 (non-muscle)
CFL2 cofilin 2 (muscle)
CHD5 chromodomain helicase DNA binding protein 5
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHM choroideremia (Rab escort protein 1)
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CHSY1 chondroitin sulfate synthase 1
CHUK conserved helix-loop-helix ubiquitous kinase
CKB creatine kinase, brain
CLUAP1 clusterin associated protein 1
CMTM5 CKLF-like MARVEL transmembrane domain containing 5
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COL18A1 collagen, type XVIII, alpha 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COMT catechol-O-methyltransferase
CP ceruloplasmin (ferroxidase)
CPA6 carboxypeptidase A6
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CRH corticotropin releasing hormone
CRHR1 corticotropin releasing hormone receptor 1
CSK c-src tyrosine kinase
CSMD1 CUB and Sushi multiple domains 1
CSNK1A1 casein kinase 1, alpha 1
CST1 cystatin SN
CTCF CCCTC-binding factor (zinc finger protein)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTSB cathepsin B
CTSK cathepsin K
CTSL cathepsin L
CUEDC2 CUE domain containing 2
CUL4A cullin 4A
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CYBA cytochrome b-245, alpha polypeptide
CYLD cylindromatosis (turban tumor syndrome)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP3A cytochrome P450, family 3, subfamily A
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DAB2IP DAB2 interacting protein
DAPK1 death-associated protein kinase 1
DAPK2 death-associated protein kinase 2
DCK deoxycytidine kinase
DDB1 damage-specific DNA binding protein 1, 127kDa
DDIT4 DNA-damage-inducible transcript 4
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DEK DEK proto-oncogene
DHRS4 dehydrogenase/reductase (SDR family) member 4
DICER1 dicer 1, ribonuclease type III
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DKC1 dyskeratosis congenita 1, dyskerin
DLC1 DLC1 Rho GTPase activating protein
DLEC1 deleted in lung and esophageal cancer 1
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DMD dystrophin
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPP10 dipeptidyl-peptidase 10 (non-functional)
DPP3 dipeptidyl-peptidase 3
DPP6 dipeptidyl-peptidase 6
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
DUSP1 dual specificity phosphatase 1
DUSP12 dual specificity phosphatase 12
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
E2F1 E2F transcription factor 1
E2F3 E2F transcription factor 3
E4F1 E4F transcription factor 1
ECT2 epithelial cell transforming 2
EDA ectodysplasin A
EDN2 endothelin 2
EDN3 endothelin 3
EDNRB endothelin receptor type B
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EGFR epidermal growth factor receptor
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EI24 etoposide induced 2.4
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELANE elastase, neutrophil expressed
ELK1 ELK1, member of ETS oncogene family
ENDOG endonuclease G
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPCAM epithelial cell adhesion molecule
EPHA7 EPH receptor A7
EPHB2 EPH receptor B2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ETV4 ets variant 4
ETV6 ets variant 6
EXT1 exostosin glycosyltransferase 1
EXT2 exostosin glycosyltransferase 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F12 coagulation factor XII (Hageman factor)
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F8 coagulation factor VIII, procoagulant component
FAAH2 fatty acid amide hydrolase 2
FANCB Fanconi anemia, complementation group B
FANCC Fanconi anemia, complementation group C
FANCF Fanconi anemia, complementation group F
FANCM Fanconi anemia, complementation group M
FBP1 fructose-1,6-bisphosphatase 1
FBXO18 F-box protein, helicase, 18
FBXO32 F-box protein 32
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
FH fumarate hydratase
FHIT fragile histidine triad
FLCN folliculin
FLNA filamin A, alpha
FLT4 fms-related tyrosine kinase 4
FMR1 fragile X mental retardation 1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FOXP3 forkhead box P3
FOXQ1 forkhead box Q1
FRMD7 FERM domain containing 7
FURIN furin (paired basic amino acid cleaving enzyme)
FXYD1 FXYD domain containing ion transport regulator 1
FXYD3 FXYD domain containing ion transport regulator 3
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAP GABA(A) receptor-associated protein
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GAS6 growth arrest-specific 6
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA4 GATA binding protein 4
GATA5 GATA binding protein 5
GCG glucagon
GH1 growth hormone 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GJA1 gap junction protein, alpha 1, 43kDa
GJB2 gap junction protein, beta 2, 26kDa
GMNN geminin, DNA replication inhibitor
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNMT glycine N-methyltransferase
GPER1 G protein-coupled estrogen receptor 1
GPR33 G protein-coupled receptor 33 (gene/pseudogene)
GPX3 glutathione peroxidase 3
GRN granulin
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
H2AFX H2A histone family, member X
H2AFY H2A histone family, member Y
HDAC2 histone deacetylase 2
HES1 hes family bHLH transcription factor 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIC1 hypermethylated in cancer 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIPK1 homeodomain interacting protein kinase 1
HIPK2 homeodomain interacting protein kinase 2
HK1 hexokinase 1
HK2 hexokinase 2
HLTF helicase-like transcription factor
HMGA1 high mobility group AT-hook 1
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HNMT histamine N-methyltransferase
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HOXA2 homeobox A2
HOXA5 homeobox A5
HOXD3 homeobox D3
HRAS Harvey rat sarcoma viral oncogene homolog
HRH4 histamine receptor H4
HRK harakiri, BCL2 interacting protein
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSF1 heat shock transcription factor 1
HSF2 heat shock transcription factor 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA4 heat shock 70kDa protein 4
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDE insulin-degrading enzyme
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGFBP1 insulin-like growth factor binding protein 1
IGFBP7 insulin-like growth factor binding protein 7
IGFBPL1 insulin-like growth factor binding protein-like 1
IGHD immunoglobulin heavy constant delta
IGK immunoglobulin kappa locus
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1B interleukin 1, beta
IL32 interleukin 32
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
ILK integrin-linked kinase
ING1 inhibitor of growth family, member 1
ING4 inhibitor of growth family, member 4
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INS insulin
IRF3 interferon regulatory factor 3
IRF5 interferon regulatory factor 5
IRF7 interferon regulatory factor 7
IRF8 interferon regulatory factor 8
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
JAG1 jagged 1
JAK2 Janus kinase 2
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNIP2 Kv channel interacting protein 2
KCNIP4 Kv channel interacting protein 4
KCNJ18 potassium channel, inwardly rectifying subfamily J, member 18
KCNK3 potassium channel, two pore domain subfamily K, member 3
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
KCTD11 potassium channel tetramerization domain containing 11
KDM5C lysine (K)-specific demethylase 5C
KIAA1524 KIAA1524
KLF11 Kruppel-like factor 11
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KLK10 kallikrein-related peptidase 10
KLK3 kallikrein-related peptidase 3
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LATS2 large tumor suppressor kinase 2
LECT2 leukocyte cell-derived chemotaxin 2
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LHCGR luteinizing hormone/choriogonadotropin receptor
LIFR leukemia inhibitory factor receptor alpha
LIMD1 LIM domains containing 1
LIMK1 LIM domain kinase 1
LIN28B lin-28 homolog B (C. elegans)
LIN9 lin-9 DREAM MuvB core complex component
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMAN1 lectin, mannose-binding, 1
LMNA lamin A/C
LPL lipoprotein lipase
LRP1B low density lipoprotein receptor-related protein 1B
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC4 leucine rich repeat containing 4
LRRK2 leucine-rich repeat kinase 2
LTF lactotransferrin
LYN LYN proto-oncogene, Src family tyrosine kinase
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L1BP MAD2L1 binding protein
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAL mal, T-cell differentiation protein
MALT1 MALT1 paracaspase
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MAPT microtubule-associated protein tau
MAVS mitochondrial antiviral signaling protein
MBD1 methyl-CpG binding domain protein 1
MBNL1 muscleblind-like splicing regulator 1
MBNL2 muscleblind-like splicing regulator 2
MCL1 myeloid cell leukemia 1
MCM4 minichromosome maintenance complex component 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MECP2 methyl CpG binding protein 2
MEN1 multiple endocrine neoplasia I
MEPE matrix extracellular phosphoglycoprotein
MET MET proto-oncogene, receptor tyrosine kinase
MGA MGA, MAX dimerization protein
MGMT O-6-methylguanine-DNA methyltransferase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MINA MYC induced nuclear antigen
MIR10B microRNA 10b
MIR129-2 microRNA 129-2
MIR143 microRNA 143
MIR145 microRNA 145
MIR146B microRNA 146b
MIR17 microRNA 17
MIR203A microRNA 203a
MIR21 microRNA 21
MIR34A microRNA 34a
MIR34B microRNA 34b
MIR34C microRNA 34c
MIR421 microRNA 421
MIR7-1 microRNA 7-1
MLH1 mutL homolog 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MME membrane metallo-endopeptidase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MOXD2P monooxygenase, DBH-like 2, pseudogene
MPO myeloperoxidase
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MT1E metallothionein 1E
MTAP methylthioadenosine phosphorylase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTM1 myotubularin 1
MTNR1A melatonin receptor 1A
MTNR1B melatonin receptor 1B
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUTYH mutY homolog
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYEOV myeloma overexpressed
MYO1A myosin IA
MYO5B myosin VB
MYOCD myocardin
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NBN nibrin
NDN necdin, melanoma antigen (MAGE) family member
NDRG2 NDRG family member 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLRC4 NLR family, CARD domain containing 4
NME1 NME/NM23 nucleoside diphosphate kinase 1
NMU neuromedin U
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH3 notch 3
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPR2 natriuretic peptide receptor 2
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
NUTF2 nuclear transport factor 2
NUTM1 NUT midline carcinoma, family member 1
OFD1 oral-facial-digital syndrome 1
OGDHL oxoglutarate dehydrogenase-like
OGG1 8-oxoguanine DNA glycosylase
OPCML opioid binding protein/cell adhesion molecule-like
ORAI1 ORAI calcium release-activated calcium modulator 1
ORAI2 ORAI calcium release-activated calcium modulator 2
ORAI3 ORAI calcium release-activated calcium modulator 3
OSCP1 organic solute carrier partner 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PALB2 partner and localizer of BRCA2
PAM peptidylglycine alpha-amidating monooxygenase
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PAX5 paired box 5
PBRM1 polybromo 1
PBX1 pre-B-cell leukemia homeobox 1
PCDH8 protocadherin 8
PCGF2 polycomb group ring finger 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDLIM4 PDZ and LIM domain 4
PDPK1 3-phosphoinositide dependent protein kinase 1
PDX1 pancreatic and duodenal homeobox 1
PENK proenkephalin
PER3 period circadian clock 3
PFN1 profilin 1
PGAM4 phosphoglycerate mutase family member 4
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PHPT1 phosphohistidine phosphatase 1
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIKFYVE phosphoinositide kinase, FYVE finger containing
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKD2L1 polycystic kidney disease 2-like 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG1 phospholipase C, gamma 1
PLD2 phospholipase D2
PLG plasminogen
PLTP phospholipid transfer protein
PLXNB3 plexin B3
PLXND1 plexin D1
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLI polymerase (DNA directed) iota
POLL polymerase (DNA directed), lambda
POMC proopiomelanocortin
PPARG peroxisome proliferator-activated receptor gamma
PPID peptidylprolyl isomerase D
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRDM1 PR domain containing 1, with ZNF domain
PRDM2 PR domain containing 2, with ZNF domain
PRDM5 PR domain containing 5
PRDX6 peroxiredoxin 6
PREP prolyl endopeptidase
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCDBP protein kinase C, delta binding protein
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRNP prion protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROX1 prospero homeobox 1
PTEN phosphatase and tensin homolog
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTK2 protein tyrosine kinase 2
PTK7 protein tyrosine kinase 7 (inactive)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTTG1 pituitary tumor-transforming 1
PXN paxillin
PYCARD PYD and CARD domain containing
RAB32 RAB32, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RACGAP1 Rac GTPase activating protein 1
RAD50 RAD50 homolog (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAN RAN, member RAS oncogene family
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RARB retinoic acid receptor, beta
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RASD1 RAS, dexamethasone-induced 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RB1 retinoblastoma 1
RBL2 retinoblastoma-like 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELN reelin
RET ret proto-oncogene
RGMA repulsive guidance molecule family member a
RHEB Ras homolog enriched in brain
RHOA ras homolog family member A
RHOJ ras homolog family member J
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF43 ring finger protein 43
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPE65 retinal pigment epithelium-specific protein 65kDa
RPL22 ribosomal protein L22
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRAD Ras-related associated with diabetes
RRAS related RAS viral (r-ras) oncogene homolog
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
RUNX3 runt-related transcription factor 3
S100B S100 calcium binding protein B
SAE1 SUMO1 activating enzyme subunit 1
SAMD9L sterile alpha motif domain containing 9-like
SAMHD1 SAM domain and HD domain 1
SARAF store-operated calcium entry-associated regulatory factor
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG5 secretogranin V
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SCN3B sodium channel, voltage gated, type III beta subunit
SCN4A sodium channel, voltage gated, type IV alpha subunit
SCN4B sodium channel, voltage gated, type IV beta subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SDC4 syndecan 4
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SELT selenoprotein T
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEPN1 selenoprotein N, 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SET SET nuclear proto-oncogene
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SFTPA1 surfactant protein A1
SFTPD surfactant protein D
SH3GL2 SH3-domain GRB2-like 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHH sonic hedgehog
SHOX short stature homeobox
SIRT1 sirtuin 1
SIRT3 sirtuin 3
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLIT2 slit homolog 2 (Drosophila)
SMAD1 SMAD family member 1
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOX1 SRY (sex determining region Y)-box 1
SOX4 SRY (sex determining region Y)-box 4
SOX7 SRY (sex determining region Y)-box 7
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPEN spen family transcriptional repressor
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRD5A3 steroid 5 alpha-reductase 3
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRSF1 serine/arginine-rich splicing factor 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
ST7 suppression of tumorigenicity 7
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STIM1 stromal interaction molecule 1
STK11 serine/threonine kinase 11
STK38 serine/threonine kinase 38
STK4 serine/threonine kinase 4
SULF2 sulfatase 2
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SYT8 synaptotagmin VIII
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TACSTD2 tumor-associated calcium signal transducer 2
TADA3 transcriptional adaptor 3
TBP TATA box binding protein
TCF4 transcription factor 4
TDP1 tyrosyl-DNA phosphodiesterase 1
TERT telomerase reverse transcriptase
TES testin LIM domain protein
TET2 tet methylcytosine dioxygenase 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TFRC transferrin receptor
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
THBS2 thrombospondin 2
THBS4 thrombospondin 4
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
THSD1 thrombospondin, type I, domain containing 1
TICAM1 toll-like receptor adaptor molecule 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLX1 T-cell leukemia homeobox 1
TMPRSS2 transmembrane protease, serine 2
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TPP1 tripeptidyl peptidase I
TRAF3 TNF receptor-associated factor 3
TRIM37 tripartite motif containing 37
TRIP13 thyroid hormone receptor interactor 13
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TTK TTK protein kinase
TUSC2 tumor suppressor candidate 2
TUSC3 tumor suppressor candidate 3
TWIST1 twist family bHLH transcription factor 1
TWIST2 twist family bHLH transcription factor 2
UBA2 ubiquitin-like modifier activating enzyme 2
UBE2C ubiquitin-conjugating enzyme E2C
UBE3A ubiquitin protein ligase E3A
UBE4B ubiquitination factor E4B
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
UNC5C unc-5 homolog C (C. elegans)
UOX urate oxidase, pseudogene
UQCRH ubiquinol-cytochrome c reductase hinge protein
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WEE1 WEE1 G2 checkpoint kinase
WIF1 WNT inhibitory factor 1
WNT1 wingless-type MMTV integration site family, member 1
WNT5A wingless-type MMTV integration site family, member 5A
WRN Werner syndrome, RecQ helicase-like
WWOX WW domain containing oxidoreductase
WWP1 WW domain containing E3 ubiquitin protein ligase 1
XDH xanthine dehydrogenase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XIST X inactive specific transcript (non-protein coding)
XPC xeroderma pigmentosum, complementation group C
XPO6 exportin 6
YAP1 Yes-associated protein 1
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
YY1 YY1 transcription factor
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZEB1 zinc finger E-box binding homeobox 1
ZIC1 Zic family member 1
ZMYND10 zinc finger, MYND-type containing 10
ZNF746 zinc finger protein 746