impaired smooth muscle contractility Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description inability or reduced ability of the smooth muscle to shorten or to develop increased tension (Mammalian Phenotype Ontology, MP_0000740)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000740
Similar Terms
Downloads & Tools

Genes

27 gene mutations causing the impaired smooth muscle contractility phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ASIC2 acid sensing (proton gated) ion channel 2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
CAV1 caveolin 1, caveolae protein, 22kDa
CHRM2 cholinergic receptor, muscarinic 2
CHRM3 cholinergic receptor, muscarinic 3
CHRM4 cholinergic receptor, muscarinic 4
DLG1 discs, large homolog 1 (Drosophila)
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
FGF2 fibroblast growth factor 2 (basic)
IL10 interleukin 10
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
MRVI1 murine retrovirus integration site 1 homolog
MYH11 myosin, heavy chain 11, smooth muscle
NCF1 neutrophil cytosolic factor 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRTN neurturin
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PRKG1 protein kinase, cGMP-dependent, type I
REN renin
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMTN smoothelin
SMTNL1 smoothelin-like 1