impaired macrophage chemotaxis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced diffusion or accumulation of macrophages in tissues or cells in response to a wide variety of substances released at the sites of inflammatory reactions (Mammalian Phenotype Ontology, MP_0003799)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003799
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Genes

36 gene mutations causing the impaired macrophage chemotaxis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ANGPTL2 angiopoietin-like 2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
CCL13 chemokine (C-C motif) ligand 13
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CMKLR1 chemerin chemokine-like receptor 1
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR3 chemokine (C-X-C motif) receptor 3
FLT1 fms-related tyrosine kinase 1
FPR2 formyl peptide receptor 2
GPR132 G protein-coupled receptor 132
IL4R interleukin 4 receptor
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JMJD6 jumonji domain containing 6
LGALS3 lectin, galactoside-binding, soluble, 3
LITAF lipopolysaccharide-induced TNF factor
MMP7 matrix metallopeptidase 7
MYO9B myosin IXB
NINJ1 ninjurin 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAU plasminogen activator, urokinase
PLEC plectin
PTGES prostaglandin E synthase
PTK2B protein tyrosine kinase 2 beta
PTN pleiotrophin
REL v-rel avian reticuloendotheliosis viral oncogene homolog
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
S100A4 S100 calcium binding protein A4
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SPP1 secreted phosphoprotein 1
TRAF3IP2 TRAF3 interacting protein 2
TRPV2 transient receptor potential cation channel, subfamily V, member 2