impaired humoral immune response Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description impaired response of the immune system that mediates secreted antibodies produced in B cells (Mammalian Phenotype Ontology, MP_0020154)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0020154
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Genes

5 gene mutations causing the impaired humoral immune response phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD4 CD4 molecule
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
THEMIS thymocyte selection associated
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TRAF3 TNF receptor-associated factor 3