impaired granulocyte bactericidal activity Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description inability or reduced ability of neutrophils, eosinophils, or basophils to kill bacteria (Mammalian Phenotype Ontology, MP_0005074)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005074
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Genes

8 gene mutations causing the impaired granulocyte bactericidal activity phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD47 CD47 molecule
FCMR Fc fragment of IgM receptor
G6PC3 glucose 6 phosphatase, catalytic, 3
NCF1 neutrophil cytosolic factor 1
PGLYRP1 peptidoglycan recognition protein 1
PLAU plasminogen activator, urokinase
SLAMF6 SLAM family member 6
SYK spleen tyrosine kinase