impaired fibroblast cell migration Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description failure of cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium (Mammalian Phenotype Ontology, MP_0011707)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011707
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Genes

9 gene mutations causing the impaired fibroblast cell migration phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
CYLD cylindromatosis (turban tumor syndrome)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MTSS1 metastasis suppressor 1
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
S1PR1 sphingosine-1-phosphate receptor 1
TGS1 trimethylguanosine synthase 1
WDPCP WD repeat containing planar cell polarity effector
ZYX zyxin