impaired eosinophil recruitment Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced diffusion or accumulation of eosinophils in tissues or cells in response to a wide variety of substances released at the sites of inflammatory reactions (Mammalian Phenotype Ontology, MP_0008723)
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15 gene mutations causing the impaired eosinophil recruitment phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CCL11 chemokine (C-C motif) ligand 11
CCR3 chemokine (C-C motif) receptor 3
CCR6 chemokine (C-C motif) receptor 6
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
IL13 interleukin 13
IL21R interleukin 21 receptor
IL4 interleukin 4
KDM6B lysine (K)-specific demethylase 6B
LTB4R leukotriene B4 receptor
PTGDR2 prostaglandin D2 receptor 2
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TPSAB1 tryptase alpha/beta 1
TRAF3IP2 TRAF3 interacting protein 2