immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa. (Gene Ontology, GO_0002415)
External Link http://amigo.geneontology.org/amigo/term/GO:0002415
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Genes

2 genes participating in the immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
PIGR polymeric immunoglobulin receptor
RAB17 RAB17, member RAS oncogene family