immune system disease Gene Set

Dataset DISEASES Curated Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A disease of anatomical entity that is located_in the immune system. (Human Disease Ontology, DOID_2914)
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Genes

180 genes involed in the disease immune system disease from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ADA adenosine deaminase
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AK1 adenylate kinase 1
ALAS2 5'-aminolevulinate synthase 2
ALDOA aldolase A, fructose-bisphosphate
ANK1 ankyrin 1, erythrocytic
APITD1 apoptosis-inducing, TAF9-like domain 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BLK BLK proto-oncogene, Src family tyrosine kinase
BPGM 2,3-bisphosphoglycerate mutase
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTK Bruton agammaglobulinemia tyrosine kinase
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD19 CD19 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD46 CD46 molecule, complement regulatory protein
CD59 CD59 molecule, complement regulatory protein
CD81 CD81 molecule
CDAN1 codanin 1
CFB complement factor B
CFH complement factor H
CFHR5 complement factor H-related 5
CFI complement factor I
CIITA class II, major histocompatibility complex, transactivator
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
DGKE diacylglycerol kinase, epsilon 64kDa
DNASE1 deoxyribonuclease I
DNASE1L3 deoxyribonuclease I-like 3
EGLN1 egl-9 family hypoxia-inducible factor 1
ELANE elastase, neutrophil expressed
EPAS1 endothelial PAS domain protein 1
EPB41 erythrocyte membrane protein band 4.1
EPB42 erythrocyte membrane protein band 4.2
EPOR erythropoietin receptor
ERCC4 excision repair cross-complementation group 4
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
F9 coagulation factor IX
FANCA Fanconi anemia, complementation group A
FANCB Fanconi anemia, complementation group B
FANCC Fanconi anemia, complementation group C
FANCD2 Fanconi anemia, complementation group D2
FANCE Fanconi anemia, complementation group E
FANCF Fanconi anemia, complementation group F
FANCG Fanconi anemia, complementation group G
FANCI Fanconi anemia, complementation group I
FANCL Fanconi anemia, complementation group L
FANCM Fanconi anemia, complementation group M
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FLT4 fms-related tyrosine kinase 4
G6PC3 glucose 6 phosphatase, catalytic, 3
G6PD glucose-6-phosphate dehydrogenase
GCLC glutamate-cysteine ligase, catalytic subunit
GFI1 growth factor independent 1 transcription repressor
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP1BB glycoprotein Ib (platelet), beta polypeptide
GP9 glycoprotein IX (platelet)
GPI glucose-6-phosphate isomerase
GSS glutathione synthetase
HAX1 HCLS1 associated protein X-1
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HBB hemoglobin, beta
HFE hemochromatosis
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HRG histidine-rich glycoprotein
ICOS inducible T-cell co-stimulator
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL2RA interleukin 2 receptor, alpha
IL2RG interleukin 2 receptor, gamma
IL7R interleukin 7 receptor
IRF5 interferon regulatory factor 5
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITPKC inositol-trisphosphate 3-kinase C
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5
KLF1 Kruppel-like factor 1 (erythroid)
KRAS Kirsten rat sarcoma viral oncogene homolog
LPIN2 lipin 2
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LTK leukocyte receptor tyrosine kinase
MBP myelin basic protein
MEFV Mediterranean fever
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NCF1 neutrophil cytosolic factor 1
NCF1C neutrophil cytosolic factor 1C pseudogene
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NPC1 Niemann-Pick disease, type C1
NPC2 Niemann-Pick disease, type C2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PALB2 partner and localizer of BRCA2
PDCD1 programmed cell death 1
PGK1 phosphoglycerate kinase 1
PIEZO1 piezo-type mechanosensitive ion channel component 1
PKLR pyruvate kinase, liver and RBC
PLG plasminogen
PNP purine nucleoside phosphorylase
PRF1 perforin 1 (pore forming protein)
PRKCD protein kinase C, delta
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROS1 protein S (alpha)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
RAD51C RAD51 paralog C
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RFXANK regulatory factor X-associated ankyrin-containing protein
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPL11 ribosomal protein L11
RPL15 ribosomal protein L15
RPL26 ribosomal protein L26
RPL35A ribosomal protein L35a
RPL5 ribosomal protein L5
RPS10 ribosomal protein S10
RPS17 ribosomal protein S17
RPS19 ribosomal protein S19
RPS24 ribosomal protein S24
RPS26 ribosomal protein S26
RPS29 ribosomal protein S29
RPS7 ribosomal protein S7
SAA1 serum amyloid A1
SCGB3A2 secretoglobin, family 3A, member 2
SEC23B Sec23 homolog B (S. cerevisiae)
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLX4 SLX4 structure-specific endonuclease subunit
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SPTA1 spectrin, alpha, erythrocytic 1
SPTB spectrin, beta, erythrocytic
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STRA13 stimulated by retinoic acid 13
STX11 syntaxin 11
STXBP2 syntaxin binding protein 2
TET2 tet methylcytosine dioxygenase 2
TG thyroglobulin
THBD thrombomodulin
TLR5 toll-like receptor 5
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TPI1 triosephosphate isomerase 1
TREX1 three prime repair exonuclease 1
TSHR thyroid stimulating hormone receptor
UNC13D unc-13 homolog D (C. elegans)
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VWF von Willebrand factor
WAS Wiskott-Aldrich syndrome
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa