immune response-activating cell surface receptor signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a cell capable of activating or perpetuating an immune response. (Gene Ontology, GO_0002429)
External Link http://amigo.geneontology.org/amigo/term/GO:0002429
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Genes

181 genes participating in the immune response-activating cell surface receptor signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABI1 abl-interactor 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTB actin, beta
ACTG1 actin gamma 1
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
BAIAP2 BAI1-associated protein 2
BAX BCL2-associated X protein
BCAR1 breast cancer anti-estrogen resistance 1
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BLK BLK proto-oncogene, Src family tyrosine kinase
BMX BMX non-receptor tyrosine kinase
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
BTK Bruton agammaglobulinemia tyrosine kinase
BTN3A1 butyrophilin, subfamily 3, member A1
C3AR1 complement component 3a receptor 1
C5AR1 complement component 5a receptor 1
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CARD11 caspase recruitment domain family, member 11
CD19 CD19 molecule
CD247 CD247 molecule
CD28 CD28 molecule
CD38 CD38 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CDC42 cell division cycle 42
CFL1 cofilin 1 (non-muscle)
CHUK conserved helix-loop-helix ubiquitous kinase
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSK c-src tyrosine kinase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYFIP2 cytoplasmic FMR1 interacting protein 2
DOCK1 dedicator of cytokinesis 1
ELMO1 engulfment and cell motility 1
ELMO2 engulfment and cell motility 2
ENAH enabled homolog (Drosophila)
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FFAR2 free fatty acid receptor 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FOXP3 forkhead box P3
FYB FYN binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GATA3 GATA binding protein 3
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
HCK HCK proto-oncogene, Src family tyrosine kinase
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITK IL2-inducible T-cell kinase
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KLHL6 kelch-like family member 6
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LAX1 lymphocyte transmembrane adaptor 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LIME1 Lck interacting transmembrane adaptor 1
LIMK1 LIM domain kinase 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MALT1 MALT1 paracaspase
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MEF2C myocyte enhancer factor 2C
MICB MHC class I polypeptide-related sequence B
MNDA myeloid cell nuclear differentiation antigen
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYO10 myosin X
MYO1C myosin IC
MYO1G myosin IG
NCK1 NCK adaptor protein 1
NCKAP1 NCK-associated protein 1
NCKAP1L NCK-associated protein 1-like
NCKIPSD NCK interacting protein with SH3 domain
NFAM1 NFAT activating protein with ITAM motif 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCQ protein kinase C, theta
PRKD2 protein kinase D2
PSEN1 presenilin 1
PSEN2 presenilin 2
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFTN1 raftlin, lipid raft linker 1
RIPK2 receptor-interacting serine-threonine kinase 2
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
RNF31 ring finger protein 31
RPS27A ribosomal protein S27a
SH2B2 SH2B adaptor protein 2
SKAP1 src kinase associated phosphoprotein 1
SLA2 Src-like-adaptor 2
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STK11 serine/threonine kinase 11
STOML2 stomatin (EPB72)-like 2
SYK spleen tyrosine kinase
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TEC tec protein tyrosine kinase
THEMIS thymocyte selection associated
THEMIS2 thymocyte selection associated family member 2
THY1 Thy-1 cell surface antigen
TLR2 toll-like receptor 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAT1 T cell receptor associated transmembrane adaptor 1
TXK TXK tyrosine kinase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2N ubiquitin-conjugating enzyme E2N
VASP vasodilator-stimulated phosphoprotein
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
WAS Wiskott-Aldrich syndrome
WASF2 WAS protein family, member 2
WASL Wiskott-Aldrich syndrome-like
WIPF1 WAS/WASL interacting protein family, member 1
WIPF2 WAS/WASL interacting protein family, member 2
WIPF3 WAS/WASL interacting protein family, member 3
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa