immune effector process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process of the immune system that can potentially contribute to an immune response. (Gene Ontology, GO_0002252)
External Link http://amigo.geneontology.org/amigo/term/GO:0002252
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Genes

394 genes participating in the immune effector process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABI1 abl-interactor 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACTB actin, beta
ACTG1 actin gamma 1
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADA adenosine deaminase
ADAM17 ADAM metallopeptidase domain 17
ADAR adenosine deaminase, RNA-specific
ADARB1 adenosine deaminase, RNA-specific, B1
AICDA activation-induced cytidine deaminase
ANXA3 annexin A3
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ATG7 autophagy related 7
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BAIAP2 BAI1-associated protein 2
BATF basic leucine zipper transcription factor, ATF-like
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL3 B-cell CLL/lymphoma 3
BECN1 beclin 1, autophagy related
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
BST2 bone marrow stromal cell antigen 2
BTN3A2 butyrophilin, subfamily 3, member A2
BTN3A3 butyrophilin, subfamily 3, member A3
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QBP complement component 1, q subcomponent binding protein
C1QC complement component 1, q subcomponent, C chain
C1R complement component 1, r subcomponent
C1RL complement component 1, r subcomponent-like
C1S complement component 1, s subcomponent
C2 complement component 2
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
C5 complement component 5
C6 complement component 6
C7 complement component 7
C8A complement component 8, alpha polypeptide
C8B complement component 8, beta polypeptide
C8G complement component 8, gamma polypeptide
C9 complement component 9
CADM1 cell adhesion molecule 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CARD9 caspase recruitment domain family, member 9
CCL3 chemokine (C-C motif) ligand 3
CD180 CD180 molecule
CD1C CD1c molecule
CD207 CD207 molecule, langerin
CD247 CD247 molecule
CD27 CD27 molecule
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD46 CD46 molecule, complement regulatory protein
CD47 CD47 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD86 CD86 molecule
CD8A CD8a molecule
CDC42 cell division cycle 42
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CFB complement factor B
CFD complement factor D (adipsin)
CFH complement factor H
CFHR1 complement factor H-related 1
CFHR5 complement factor H-related 5
CFI complement factor I
CFL1 cofilin 1 (non-muscle)
CFP complement factor properdin
CHGA chromogranin A
CLEC2A C-type lectin domain family 2, member A
CLU clusterin
CPLX2 complexin 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRCP CGRP receptor component
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CRTAM cytotoxic and regulatory T cell molecule
CTSC cathepsin C
CTSG cathepsin G
CTSH cathepsin H
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL9 chemokine (C-X-C motif) ligand 9
CYFIP2 cytoplasmic FMR1 interacting protein 2
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDIT4 DNA-damage-inducible transcript 4
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DEFA3 defensin, alpha 3, neutrophil-specific
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DICER1 dicer 1, ribonuclease type III
DLG1 discs, large homolog 1 (Drosophila)
DMBT1 deleted in malignant brain tumors 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DOCK1 dedicator of cytokinesis 1
DOCK2 dedicator of cytokinesis 2
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ELANE elastase, neutrophil expressed
ELMO1 engulfment and cell motility 1
ELMO2 engulfment and cell motility 2
ELMOD2 ELMO/CED-12 domain containing 2
EMP2 epithelial membrane protein 2
EOMES eomesodermin
ERCC1 excision repair cross-complementation group 1
EXO1 exonuclease 1
EXOSC3 exosome component 3
EXOSC4 exosome component 4
EXOSC5 exosome component 5
EXOSC6 exosome component 6
F2RL1 coagulation factor II (thrombin) receptor-like 1
FADD Fas (TNFRSF6)-associated via death domain
FAM111A family with sequence similarity 111, member A
FAS Fas cell surface death receptor
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FGR FGR proto-oncogene, Src family tyrosine kinase
FOXP1 forkhead box P1
FOXP3 forkhead box P3
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FYN FYN proto-oncogene, Src family tyrosine kinase
GAPT GRB2-binding adaptor protein, transmembrane
GATA3 GATA binding protein 3
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GBP1 guanylate binding protein 1, interferon-inducible
GBP3 guanylate binding protein 3
GNL1 guanine nucleotide binding protein-like 1
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPR183 G protein-coupled receptor 183
GRB2 growth factor receptor-bound protein 2
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HCK HCK proto-oncogene, Src family tyrosine kinase
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HYAL2 hyaluronoglucosaminidase 2
ICAM1 intercellular adhesion molecule 1
IFI16 interferon, gamma-inducible protein 16
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IFNA10 interferon, alpha 10
IFNA14 interferon, alpha 14
IFNA16 interferon, alpha 16
IFNA17 interferon, alpha 17
IFNA2 interferon, alpha 2
IFNA21 interferon, alpha 21
IFNA4 interferon, alpha 4
IFNA5 interferon, alpha 5
IFNA6 interferon, alpha 6
IFNA7 interferon, alpha 7
IFNA8 interferon, alpha 8
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNB1 interferon, beta 1, fibroblast
IFNE interferon, epsilon
IFNG interferon, gamma
IFNK interferon, kappa
IFNL1 interferon, lambda 1
IFNL2 interferon, lambda 2
IFNL3 interferon, lambda 3
IFNL4 interferon, lambda 4 (gene/pseudogene)
IFNLR1 interferon, lambda receptor 1
IFNW1 interferon, omega 1
IL10RB interleukin 10 receptor, beta
IL12B interleukin 12B
IL18R1 interleukin 18 receptor 1
IL23A interleukin 23, alpha subunit p19
IL4 interleukin 4
IL6 interleukin 6
ILF3 interleukin enhancer binding factor 3, 90kDa
IRF1 interferon regulatory factor 1
IRF3 interferon regulatory factor 3
IRF5 interferon regulatory factor 5
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
ITCH itchy E3 ubiquitin protein ligase
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JAG1 jagged 1
JAGN1 jagunal homolog 1 (Drosophila)
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRF2 killer cell lectin-like receptor subfamily F, member 2
KMT2E lysine (K)-specific methyltransferase 2E
KRT1 keratin 1, type II
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LBP lipopolysaccharide binding protein
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS8 lectin, galactoside-binding, soluble, 8
LIG4 ligase IV, DNA, ATP-dependent
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LIMK1 LIM domain kinase 1
LYN LYN proto-oncogene, Src family tyrosine kinase
LYST lysosomal trafficking regulator
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2 mannan-binding lectin serine peptidase 2
MAVS mitochondrial antiviral signaling protein
MB21D1 Mab-21 domain containing 1
MBL2 mannose-binding lectin (protein C) 2, soluble
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MILR1 mast cell immunoglobulin-like receptor 1
MLH1 mutL homolog 1
MPO myeloperoxidase
MRGPRX2 MAS-related GPR, member X2
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYO10 myosin X
MYO1C myosin IC
MYO1F myosin IF
MYO1G myosin IG
NBN nibrin
NCF1 neutrophil cytosolic factor 1
NCK1 NCK adaptor protein 1
NCKAP1 NCK-associated protein 1
NCKIPSD NCK interacting protein with SH3 domain
NKX2-3 NK2 homeobox 3
NLRC5 NLR family, CARD domain containing 5
NLRP3 NLR family, pyrin domain containing 3
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OASL 2'-5'-oligoadenylate synthetase-like
OPRK1 opioid receptor, kappa 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCBP2 poly(rC) binding protein 2
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G3 phospholipase A2, group III
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCL2 phospholipase C-like 2
PLD2 phospholipase D2
PLSCR1 phospholipid scramblase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A
PRDX1 peroxiredoxin 1
PRF1 perforin 1 (pore forming protein)
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PSEN1 presenilin 1
PSEN2 presenilin 2
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTX3 pentraxin 3, long
PYCARD PYD and CARD domain containing
RAB27A RAB27A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAET1E retinoic acid early transcript 1E
RAET1G retinoic acid early transcript 1G
RAET1L retinoic acid early transcript 1L
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RC3H1 ring finger and CCCH-type domains 1
RC3H2 ring finger and CCCH-type domains 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGCC regulator of cell cycle
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF19B ring finger protein 19B
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RORA RAR-related orphan receptor A
RORC RAR-related orphan receptor C
RPS6 ribosomal protein S6
RSAD2 radical S-adenosyl methionine domain containing 2
S100A13 S100 calcium binding protein A13
SAMHD1 SAM domain and HD domain 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SH2D1B SH2 domain containing 1B
SLA2 Src-like-adaptor 2
SLAMF7 SLAM family member 7
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLFN11 schlafen family member 11
SPON2 spondin 2, extracellular matrix protein
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STX11 syntaxin 11
STXBP2 syntaxin binding protein 2
STXBP3 syntaxin binding protein 3
SUSD4 sushi domain containing 4
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYK spleen tyrosine kinase
TBK1 TANK-binding kinase 1
TICAM1 toll-like receptor adaptor molecule 1
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TMEM173 transmembrane protein 173
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TP53 tumor protein p53
TREM1 triggering receptor expressed on myeloid cells 1
TRIM11 tripartite motif containing 11
TRIM22 tripartite motif containing 22
TRIM25 tripartite motif containing 25
TRIM5 tripartite motif containing 5
TRIM56 tripartite motif containing 56
TUBB tubulin, beta class I
TUBB4B tubulin, beta 4B class IVb
TUSC2 tumor suppressor candidate 2
TYROBP TYRO protein tyrosine kinase binding protein
ULBP1 UL16 binding protein 1
ULBP2 UL16 binding protein 2
ULBP3 UL16 binding protein 3
UNC13D unc-13 homolog D (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VAMP7 vesicle-associated membrane protein 7
VAMP8 vesicle-associated membrane protein 8
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VSIG4 V-set and immunoglobulin domain containing 4
WAS Wiskott-Aldrich syndrome
WASF2 WAS protein family, member 2
WASL Wiskott-Aldrich syndrome-like
WIPF1 WAS/WASL interacting protein family, member 1
WIPF2 WAS/WASL interacting protein family, member 2
WIPF3 WAS/WASL interacting protein family, member 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZNF175 zinc finger protein 175
ZP3 zona pellucida glycoprotein 3 (sperm receptor)