imidurea-3522 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the imidurea-3522 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL8 actin-like 8
ADGRE3 adhesion G protein-coupled receptor E3
AGER advanced glycosylation end product-specific receptor
AIM2 absent in melanoma 2
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ANPEP alanyl (membrane) aminopeptidase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARID5A AT rich interactive domain 5A (MRF1-like)
ASCL1 achaete-scute family bHLH transcription factor 1
ATAT1 alpha tubulin acetyltransferase 1
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
AUTS2 autism susceptibility candidate 2
BAAT bile acid CoA:amino acid N-acyltransferase
BCO1 beta-carotene oxygenase 1
C21ORF2 chromosome 21 open reading frame 2
CAMK1 calcium/calmodulin-dependent protein kinase I
CAPN9 calpain 9
CCDC40 coiled-coil domain containing 40
CD53 CD53 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLEC4A C-type lectin domain family 4, member A
CNN3 calponin 3, acidic
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CST4 cystatin S
CTNNA2 catenin (cadherin-associated protein), alpha 2
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DHRS7 dehydrogenase/reductase (SDR family) member 7
DMPK dystrophia myotonica-protein kinase
DOCK9 dedicator of cytokinesis 9
ERCC2 excision repair cross-complementation group 2
FANCA Fanconi anemia, complementation group A
FASLG Fas ligand (TNF superfamily, member 6)
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FER1L4 fer-1-like family member 4, pseudogene (functional)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GLIPR1 GLI pathogenesis-related 1
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HFE hemochromatosis
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
ICOSLG inducible T-cell co-stimulator ligand
IGHM immunoglobulin heavy constant mu
IL11 interleukin 11
IL1RN interleukin 1 receptor antagonist
IL6R interleukin 6 receptor
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JADE2 jade family PHD finger 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KLK8 kallikrein-related peptidase 8
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAPTM5 lysosomal protein transmembrane 5
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRRN3 leucine rich repeat neuronal 3
MAPK7 mitogen-activated protein kinase 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED16 mediator complex subunit 16
MOXD1 monooxygenase, DBH-like 1
MTA2 metastasis associated 1 family, member 2
MTSS1L metastasis suppressor 1-like
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCKIPSD NCK interacting protein with SH3 domain
NCR2 natural cytotoxicity triggering receptor 2
NF2 neurofibromin 2 (merlin)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NME5 NME/NM23 family member 5
OGFR opioid growth factor receptor
OMD osteomodulin
PAWR PRKC, apoptosis, WT1, regulator
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIDD1 p53-induced death domain protein 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RPL10 ribosomal protein L10
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
S100A7 S100 calcium binding protein A7
SEC14L5 SEC14-like 5 (S. cerevisiae)
SFTPD surfactant protein D
SIK2 salt-inducible kinase 2
SIPA1 signal-induced proliferation-associated 1
SLC35G2 solute carrier family 35, member G2
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SPDEF SAM pointed domain containing ETS transcription factor
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAC SH3 and cysteine rich domain
STK11 serine/threonine kinase 11
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TGM2 transglutaminase 2
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TP63 tumor protein p63
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
VPREB3 pre-B lymphocyte 3
WDR55 WD repeat domain 55
ZFP37 ZFP37 zinc finger protein
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABI3BP ABI family, member 3 (NESH) binding protein
ARL15 ADP-ribosylation factor-like 15
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C11ORF68 chromosome 11 open reading frame 68
CCDC121 coiled-coil domain containing 121
CCNL2 cyclin L2
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CEP97 centrosomal protein 97kDa
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIDEC cell death-inducing DFFA-like effector c
CINP cyclin-dependent kinase 2 interacting protein
CXCR2 chemokine (C-X-C motif) receptor 2
DEAF1 DEAF1 transcription factor
EAF2 ELL associated factor 2
EFHD2 EF-hand domain family, member D2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHA2 EPH receptor A2
ERCC4 excision repair cross-complementation group 4
FAM46C family with sequence similarity 46, member C
FBRS fibrosin
FMO4 flavin containing monooxygenase 4
GALK1 galactokinase 1
GEMIN8 gem (nuclear organelle) associated protein 8
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH2L G patch domain containing 2-like
HIST1H1D histone cluster 1, H1d
HIST1H2BO histone cluster 1, H2bo
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IMPACT impact RWD domain protein
INPP1 inositol polyphosphate-1-phosphatase
INPP5J inositol polyphosphate-5-phosphatase J
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM8 lysine (K)-specific demethylase 8
KRT8P12 keratin 8 pseudogene 12
LIME1 Lck interacting transmembrane adaptor 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LYPD1 LY6/PLAUR domain containing 1
LYRM9 LYR motif containing 9
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MCOLN3 mucolipin 3
MEIS1 Meis homeobox 1
MGC12488
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
NBEAL2 neurobeachin-like 2
NOL12 nucleolar protein 12
PADI2 peptidyl arginine deiminase, type II
PGP phosphoglycolate phosphatase
PLA2G3 phospholipase A2, group III
PLD3 phospholipase D family, member 3
POM121 POM121 transmembrane nucleoporin
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PROS1 protein S (alpha)
RAB17 RAB17, member RAS oncogene family
RASL11B RAS-like, family 11, member B
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF25 ring finger protein 25
RPAP1 RNA polymerase II associated protein 1
SCAI suppressor of cancer cell invasion
SCML2 sex comb on midleg-like 2 (Drosophila)
SCRN3 secernin 3
SH2D4A SH2 domain containing 4A
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SP1 Sp1 transcription factor
SPAG4 sperm associated antigen 4
SREBF1 sterol regulatory element binding transcription factor 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STRN4 striatin, calmodulin binding protein 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCP10 t-complex 10
TICAM1 toll-like receptor adaptor molecule 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM62 transmembrane protein 62
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM25 tripartite motif containing 25
TUBA3C tubulin, alpha 3c
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VASH2 vasohibin 2
WDR18 WD repeat domain 18
WDR4 WD repeat domain 4
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZDHHC11 zinc finger, DHHC-type containing 11
ZFP30 ZFP30 zinc finger protein
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF324 zinc finger protein 324
ZNF34 zinc finger protein 34
ZNF37BP zinc finger protein 37B, pseudogene
ZNF652 zinc finger protein 652