iloprost-427 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the iloprost-427 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ARRB2 arrestin, beta 2
ATG13 autophagy related 13
ATXN2 ataxin 2
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BCL9 B-cell CLL/lymphoma 9
BMP8A bone morphogenetic protein 8a
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BTBD2 BTB (POZ) domain containing 2
C1D C1D nuclear receptor corepressor
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C7ORF26 chromosome 7 open reading frame 26
CABIN1 calcineurin binding protein 1
CD19 CD19 molecule
CD44 CD44 molecule (Indian blood group)
COG5 component of oligomeric golgi complex 5
CTTN cortactin
DCLRE1C DNA cross-link repair 1C
DCN decorin
DENND5A DENN/MADD domain containing 5A
DHPS deoxyhypusine synthase
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EFNA1 ephrin-A1
EHD1 EH-domain containing 1
EID1 EP300 interacting inhibitor of differentiation 1
EMC1 ER membrane protein complex subunit 1
FAM3A family with sequence similarity 3, member A
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GFOD2 glucose-fructose oxidoreductase domain containing 2
GPN3 GPN-loop GTPase 3
GULP1 GULP, engulfment adaptor PTB domain containing 1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HIST1H4J histone cluster 1, H4j
HLA-E major histocompatibility complex, class I, E
HPX hemopexin
ICA1 islet cell autoantigen 1, 69kDa
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
KHNYN KH and NYN domain containing
KIAA1598
LIN7C lin-7 homolog C (C. elegans)
LINC00574 long intergenic non-protein coding RNA 574
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MED13L mediator complex subunit 13-like
MRC2 mannose receptor, C type 2
MRPL33 mitochondrial ribosomal protein L33
MRPS31 mitochondrial ribosomal protein S31
N4BP2L2 NEDD4 binding protein 2-like 2
NADK NAD kinase
NDC80 NDC80 kinetochore complex component
NMT1 N-myristoyltransferase 1
NUCB2 nucleobindin 2
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP prolactin-induced protein
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PMEPA1 prostate transmembrane protein, androgen induced 1
PNPLA6 patatin-like phospholipase domain containing 6
PPCS phosphopantothenoylcysteine synthetase
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PRB1 proline-rich protein BstNI subfamily 1
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RALBP1 ralA binding protein 1
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RBM5 RNA binding motif protein 5
RLN2 relaxin 2
RPL31 ribosomal protein L31
RPS2 ribosomal protein S2
RRAGD Ras-related GTP binding D
RRAS related RAS viral (r-ras) oncogene homolog
SEC23B Sec23 homolog B (S. cerevisiae)
SERINC5 serine incorporator 5
SEZ6L seizure related 6 homolog (mouse)-like
SF3A2 splicing factor 3a, subunit 2, 66kDa
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TMEM127 transmembrane protein 127
TRADD TNFRSF1A-associated via death domain
TRIM8 tripartite motif containing 8
TTLL4 tubulin tyrosine ligase-like family member 4
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VPS33B vacuolar protein sorting 33 homolog B (yeast)
WDR18 WD repeat domain 18
WWOX WW domain containing oxidoreductase
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
YLPM1 YLP motif containing 1
YME1L1 YME1-like 1 ATPase
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZC3H12A zinc finger CCCH-type containing 12A
ZFAND1 zinc finger, AN1-type domain 1
ZNF117 zinc finger protein 117
ZNF500 zinc finger protein 500
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ADAM15 ADAM metallopeptidase domain 15
ADAM23 ADAM metallopeptidase domain 23
ADORA3 adenosine A3 receptor
APCS amyloid P component, serum
ARRB1 arrestin, beta 1
ARSA arylsulfatase A
AUH AU RNA binding protein/enoyl-CoA hydratase
AXIN1 axin 1
BAHD1 bromo adjacent homology domain containing 1
BCL2L14 BCL2-like 14 (apoptosis facilitator)
C16ORF62 chromosome 16 open reading frame 62
CA5A carbonic anhydrase VA, mitochondrial
CAPG capping protein (actin filament), gelsolin-like
CCDC170 coiled-coil domain containing 170
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD82 CD82 molecule
CDH3 cadherin 3, type 1, P-cadherin (placental)
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CFAP70 cilia and flagella associated protein 70
CHD2 chromodomain helicase DNA binding protein 2
CHRM4 cholinergic receptor, muscarinic 4
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLCN6 chloride channel, voltage-sensitive 6
CLEC10A C-type lectin domain family 10, member A
CNTN1 contactin 1
CRBN cereblon
CRYAB crystallin, alpha B
CTC1 CTS telomere maintenance complex component 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNBIP1 catenin, beta interacting protein 1
CXCL10 chemokine (C-X-C motif) ligand 10
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DSCAM Down syndrome cell adhesion molecule
EFCAB1 EF-hand calcium binding domain 1
EPX eosinophil peroxidase
FAM63A family with sequence similarity 63, member A
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GALR3 galanin receptor 3
GLTP glycolipid transfer protein
GPR157 G protein-coupled receptor 157
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GSTP1 glutathione S-transferase pi 1
HOXA4 homeobox A4
HSF2BP heat shock transcription factor 2 binding protein
ICE2 interactor of little elongation complex ELL subunit 2
IDO1 indoleamine 2,3-dioxygenase 1
IRF2 interferon regulatory factor 2
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KIAA0355 KIAA0355
KLF15 Kruppel-like factor 15
KLF7 Kruppel-like factor 7 (ubiquitous)
KLK8 kallikrein-related peptidase 8
KRT32 keratin 32, type I
LGALS13 lectin, galactoside-binding, soluble, 13
MAPK10 mitogen-activated protein kinase 10
MCHR1 melanin-concentrating hormone receptor 1
METTL2B methyltransferase like 2B
MOCS3 molybdenum cofactor synthesis 3
NLK nemo-like kinase
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NXPH3 neurexophilin 3
PANX1 pannexin 1
PARG poly (ADP-ribose) glycohydrolase
PCDHB6 protocadherin beta 6
PDE8B phosphodiesterase 8B
PGC progastricsin (pepsinogen C)
PICK1 protein interacting with PRKCA 1
PLAC1 placenta-specific 1
POM121 POM121 transmembrane nucleoporin
POU4F2 POU class 4 homeobox 2
PRPH2 peripherin 2 (retinal degeneration, slow)
PSG4 pregnancy specific beta-1-glycoprotein 4
PTPRT protein tyrosine phosphatase, receptor type, T
QTRT1 queuine tRNA-ribosyltransferase 1
RDH8 retinol dehydrogenase 8 (all-trans)
RNF39 ring finger protein 39
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STARD13 StAR-related lipid transfer (START) domain containing 13
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM39B transmembrane protein 39B
TOM1 target of myb1 (chicken)
TP53TG5 TP53 target 5
TRAV8-3 T cell receptor alpha variable 8-3
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VWA1 von Willebrand factor A domain containing 1
ZFP36 ZFP36 ring finger protein
ZIC1 Zic family member 1