il 6 signaling pathway Gene Set

Dataset Biocarta Pathways
Category structural or functional annotations
Type pathway
Description Interleukin-6 signaling is involved in a wide range of biological processes such as immune regulation, inflammation, hematopoiesis and oncogenesis. A signal transducer common to all family members, gp130 activates Jak-Stat and Raf/Mek/Erk signaling pathways. (Pathway Ontology, PW_0000516)
External Link http://cgap.nci.nih.gov/Pathways/BioCarta/h_il6Pathway
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Genes

13 proteins participating in the il 6 signaling pathway pathway from the Biocarta Pathways dataset.

Symbol Name
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
GRB2 growth factor receptor-bound protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
IL6 interleukin 6
IL6R interleukin 6 receptor
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
LRPPRC leucine-rich pentatricopeptide repeat containing
PTPN11 protein tyrosine phosphatase, non-receptor type 11
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOS1 son of sevenless homolog 1 (Drosophila)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)