il 2 signaling pathway Gene Set

Dataset Biocarta Pathways
Category structural or functional annotations
Type pathway
Description Interleukin-2 is the prototypical member of the interleukin-2 family of cytokines. The signaling pathway initiated by Il-2 and the other family members activates the Jak-Stat intracellular cascade to regulate T cell, innate and adaptive immune responses. (Pathway Ontology, PW_0000907)
External Link http://cgap.nci.nih.gov/Pathways/BioCarta/h_il2Pathway
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14 proteins participating in the il 2 signaling pathway pathway from the Biocarta Pathways dataset.

Symbol Name
GRB2 growth factor receptor-bound protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
JAK1 Janus kinase 1
JAK3 Janus kinase 3
LCK LCK proto-oncogene, Src family tyrosine kinase
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOS1 son of sevenless homolog 1 (Drosophila)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
SYK spleen tyrosine kinase