ibs Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.|A syndrome that is a functional bowel disorder characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any detectable organic cause. (Experimental Factor Ontology, EFO_0000555)
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Genes

28 genes co-occuring with the biological term ibs in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADRA2A adrenoceptor alpha 2A
ADRB3 adrenoceptor beta 3
CCL16 chemokine (C-C motif) ligand 16
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHGA chromogranin A
CHRM3 cholinergic receptor, muscarinic 3
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CRHR1 corticotropin releasing hormone receptor 1
CRP C-reactive protein, pentraxin-related
FAAH fatty acid amide hydrolase
GHRL ghrelin/obestatin prepropeptide
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTT huntingtin
IL10 interleukin 10
IL6 interleukin 6
LCT lactase
MAPK14 mitogen-activated protein kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MLN motilin
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PRSS3 protease, serine, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
TACR1 tachykinin receptor 1
TLR4 toll-like receptor 4
TPH1 tryptophan hydroxylase 1