hypoxia-inducible factor-1alpha signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia. (Gene Ontology, GO_0097411)
External Link http://amigo.geneontology.org/amigo/term/GO:0097411
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Genes

2 genes participating in the hypoxia-inducible factor-1alpha signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDK3 pyruvate dehydrogenase kinase, isozyme 3