hypoplastic left heart syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A congenital heart disease characterized by abnormal development of the left-sided structures of the heart. (Human Disease Ontology, DOID_9955)
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Genes

86 genes co-occuring with the disease hypoplastic left heart syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ERAS ES cell expressed Ras 1.50886
FOXL1 forkhead box L1 1.28304
NODAL nodal growth differentiation factor 1.2495
MCTP2 multiple C2 domains, transmembrane 2 1.20742
MBTPS1 membrane-bound transcription factor peptidase, site 1 1.20656
NKX2-5 NK2 homeobox 5 1.16264
CPLX3 complexin 3 1.15198
SMYD1 SET and MYND domain containing 1 1.13163
MFAP4 microfibrillar-associated protein 4 1.0033
BMPER BMP binding endothelial regulator 0.987271
HAND1 heart and neural crest derivatives expressed 1 0.968341
B3GALTL beta 1,3-galactosyltransferase-like 0.918848
FOXC2 forkhead box C2 0.891718
EED embryonic ectoderm development 0.890488
GDF3 growth differentiation factor 3 0.852811
FOXP1 forkhead box P1 0.815924
CTHRC1 collagen triple helix repeat containing 1 0.776159
GJA1 gap junction protein, alpha 1, 43kDa 0.760231
RAI1 retinoic acid induced 1 0.736649
AMHR2 anti-Mullerian hormone receptor, type II 0.735433
CELA2A chymotrypsin-like elastase family, member 2A 0.725716
BMP3 bone morphogenetic protein 3 0.711183
EOMES eomesodermin 0.708364
BMP5 bone morphogenetic protein 5 0.702732
FOXF1 forkhead box F1 0.689092
SMC1A structural maintenance of chromosomes 1A 0.686291
TBX2 T-box 2 0.682693
ADCY5 adenylate cyclase 5 0.681495
KLHL17 kelch-like family member 17 0.676308
TNNI3 troponin I type 3 (cardiac) 0.660008
OPN3 opsin 3 0.656441
SCO2 SCO2 cytochrome c oxidase assembly protein 0.646953
TBX1 T-box 1 0.644192
NOTCH1 notch 1 0.626888
FAM155B family with sequence similarity 155, member B 0.621792
MLX MLX, MAX dimerization protein 0.606933
ACVR2A activin A receptor, type IIA 0.593674
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 0.560227
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.559839
JAG1 jagged 1 0.553239
TBX5 T-box 5 0.507273
HMGA2 high mobility group AT-hook 2 0.486266
S100B S100 calcium binding protein B 0.480566
PCCA propionyl CoA carboxylase, alpha polypeptide 0.468063
RHOB ras homolog family member B 0.463149
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.443547
PER1 period circadian clock 1 0.43941
EFS embryonal Fyn-associated substrate 0.431519
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.416896
NCOA2 nuclear receptor coactivator 2 0.413153
HMOX2 heme oxygenase 2 0.408666
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.399334
ARRB1 arrestin, beta 1 0.391513
CABIN1 calcineurin binding protein 1 0.390397
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.388909
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.382223
HSF4 heat shock transcription factor 4 0.37555
INHA inhibin, alpha 0.366671
ACVRL1 activin A receptor type II-like 1 0.338341
TEF thyrotrophic embryonic factor 0.331025
FGF19 fibroblast growth factor 19 0.3292
SCN3A sodium channel, voltage gated, type III alpha subunit 0.32774
ACE angiotensin I converting enzyme 0.323365
ACO2 aconitase 2, mitochondrial 0.319726
GLS glutaminase 0.299812
CDC25A cell division cycle 25A 0.293694
ESAM endothelial cell adhesion molecule 0.289386
PLN phospholamban 0.28616
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.275801
PTGES prostaglandin E synthase 0.264785
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.254888
HDAC2 histone deacetylase 2 0.251366
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.243995
GATA4 GATA binding protein 4 0.241895
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.212608
TNNT2 troponin T type 2 (cardiac) 0.199681
NRG1 neuregulin 1 0.199033
PLAT plasminogen activator, tissue 0.186811
PAH phenylalanine hydroxylase 0.185313
ERBB4 erb-b2 receptor tyrosine kinase 4 0.18472
GLS2 glutaminase 2 (liver, mitochondrial) 0.170789
NPPA natriuretic peptide A 0.170544
MNX1 motor neuron and pancreas homeobox 1 0.167682
CTSC cathepsin C 0.163729
ALB albumin 0.163729
PIDD1 p53-induced death domain protein 1 0.161912