hypertrophy Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Hypertrophy is the increase in the volume of an organ or tissue due to the enlargement of its component cells. (Experimental Factor Ontology, EFO_0002460)
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Genes

88 proteins co-occuring with the biological term hypertrophy in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ADRBK1 adrenergic, beta, receptor kinase 1
AGTR1 angiotensin II receptor, type 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CDK1 cyclin-dependent kinase 1
CDK9 cyclin-dependent kinase 9
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
EEF2 eukaryotic translation elongation factor 2
EGFR epidermal growth factor receptor
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELK1 ELK1, member of ETS oncogene family
EP300 E1A binding protein p300
FOXO3 forkhead box O3
FXYD1 FXYD domain containing ion transport regulator 1
GATA4 GATA binding protein 4
GJA1 gap junction protein, alpha 1, 43kDa
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HDAC2 histone deacetylase 2
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HIST2H3C histone cluster 2, H3c
HNRNPK heterogeneous nuclear ribonucleoprotein K
HSPB6 heat shock protein, alpha-crystallin-related, B6
IGF1R insulin-like growth factor 1 receptor
JPH2 junctophilin 2
JUN jun proto-oncogene
MAP4 microtubule-associated protein 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MSN moesin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYOCD myocardin
MYOZ2 myozenin 2
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NOS3 nitric oxide synthase 3 (endothelial cell)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PLN phospholamban
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCD protein kinase C, delta
PRKD1 protein kinase D1
PTK2 protein tyrosine kinase 2
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RCAN1 regulator of calcineurin 1
RHOA ras homolog family member A
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPTOR regulatory associated protein of MTOR, complex 1
RUNX3 runt-related transcription factor 3
RYR2 ryanodine receptor 2 (cardiac)
SCN5A sodium channel, voltage gated, type V alpha subunit
SDC4 syndecan 4
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TAGLN transgelin
TEAD4 TEA domain family member 4
TNNI3 troponin I type 3 (cardiac)
TP53 tumor protein p53
TPM1 tropomyosin 1 (alpha)
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TTN titin
UBTF upstream binding transcription factor, RNA polymerase I
VASP vasodilator-stimulated phosphoprotein