hypertrophic Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

224 genes co-occuring with the biological term hypertrophic in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACAN aggrecan
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTC1 actin, alpha, cardiac muscle 1
ACTN1 actinin, alpha 1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADRB3 adrenoceptor beta 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AKAP1 A kinase (PRKA) anchor protein 1
AKAP13 A kinase (PRKA) anchor protein 13
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
AR androgen receptor
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
BMP10 bone morphogenetic protein 10
BMP4 bone morphogenetic protein 4
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAPN2 calpain 2, (m/II) large subunit
CAV1 caveolin 1, caveolae protein, 22kDa
CAV3 caveolin 3
CCL2 chemokine (C-C motif) ligand 2
CCNA2 cyclin A2
CCR2 chemokine (C-C motif) receptor 2
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHRD chordin
CHUK conserved helix-loop-helix ubiquitous kinase
CLDN1 claudin 1
COA5 cytochrome c oxidase assembly factor 5
COL10A1 collagen, type X, alpha 1
COL1A2 collagen, type I, alpha 2
COL4A1 collagen, type IV, alpha 1
COL9A2 collagen, type IX, alpha 2
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CRYAB crystallin, alpha B
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DES desmin
DIABLO diablo, IAP-binding mitochondrial protein
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMPK dystrophia myotonica-protein kinase
EDN1 endothelin 1
EDN2 endothelin 2
EGFR epidermal growth factor receptor
ELAC2 elaC ribonuclease Z 2
ENG endoglin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FASLG Fas ligand (TNF superfamily, member 6)
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FHL1 four and a half LIM domains 1
FHOD3 formin homology 2 domain containing 3
FXN frataxin
GDF1 growth differentiation factor 1
GDF15 growth differentiation factor 15
GHR growth hormone receptor
GJA1 gap junction protein, alpha 1, 43kDa
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPR50 G protein-coupled receptor 50
GREM1 gremlin 1, DAN family BMP antagonist
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HDAC5 histone deacetylase 5
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPG2 heparan sulfate proteoglycan 2
HYI hydroxypyruvate isomerase (putative)
IBSP integrin-binding sialoprotein
ICAM1 intercellular adhesion molecule 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL3RA interleukin 3 receptor, alpha (low affinity)
IL6 interleukin 6
INPP5F inositol polyphosphate-5-phosphatase F
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JPH2 junctophilin 2
KDM4A lysine (K)-specific demethylase 4A
KLF10 Kruppel-like factor 10
LAMP2 lysosomal-associated membrane protein 2
LECT1 leukocyte cell derived chemotaxin 1
LEP leptin
LEPR leptin receptor
LGALS7 lectin, galactoside-binding, soluble, 7
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MBNL1 muscleblind-like splicing regulator 1
MEF2C myocyte enhancer factor 2C
MIR221 microRNA 221
MIR29A microRNA 29a
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MRPL3 mitochondrial ribosomal protein L3
MRPS22 mitochondrial ribosomal protein S22
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MT-TL1 tRNA
MTO1 mitochondrial tRNA translation optimization 1
MUC16 mucin 16, cell surface associated
MYBPC1 myosin binding protein C, slow type
MYBPC2 myosin binding protein C, fast type
MYBPC3 myosin binding protein C, cardiac
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
MYL9 myosin, light chain 9, regulatory
MYOM1 myomesin 1
MYOZ2 myozenin 2
MYPN myopalladin
NCS1 neuronal calcium sensor 1
ND1
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
NES nestin
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NKX2-5 NK2 homeobox 5
NOG noggin
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NREP neuronal regeneration related protein
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OPRM1 opioid receptor, mu 1
PCNA proliferating cell nuclear antigen
PDLIM3 PDZ and LIM domain 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLN phospholamban
PMM2 phosphomannomutase 2
POLG polymerase (DNA directed), gamma
POMC proopiomelanocortin
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRMT5 protein arginine methyltransferase 5
PRTN3 proteinase 3
PTEN phosphatase and tensin homolog
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PYGB phosphorylase, glycogen; brain
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RNR2 RNA, ribosomal cluster 2
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
S100A8 S100 calcium binding protein A8
SCO2 SCO2 cytochrome c oxidase assembly protein
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SHH sonic hedgehog
SKIL SKI-like proto-oncogene
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD7 SMAD family member 7
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC3 structural maintenance of chromosomes 3
SNAI2 snail family zinc finger 2
SOX9 SRY (sex determining region Y)-box 9
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SURF1 surfeit 1
TCAP titin-cap
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFBR1 transforming growth factor, beta receptor 1
TGM2 transglutaminase 2
TIMP2 TIMP metallopeptidase inhibitor 2
TLN1 talin 1
TLN2 talin 2
TLR4 toll-like receptor 4
TMEM70 transmembrane protein 70
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNNC1 troponin C type 1 (slow)
TNNI3 troponin I type 3 (cardiac)
TNNI3K TNNI3 interacting kinase
TNNT1 troponin T type 1 (skeletal, slow)
TNNT2 troponin T type 2 (cardiac)
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TPM1 tropomyosin 1 (alpha)
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TRIP10 thyroid hormone receptor interactor 10
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TXN thioredoxin
USP15 ubiquitin specific peptidase 15
VCL vinculin
VWF von Willebrand factor
WISP3 WNT1 inducible signaling pathway protein 3
YAP1 Yes-associated protein 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK