hypertension Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000231
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Genes

41 gene mutations causing the hypertension phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACE2 angiotensin I converting enzyme 2
ADD2 adducin 2 (beta)
AGXT2 alanine--glyoxylate aminotransferase 2
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CHGA chromogranin A
COMT catechol-O-methyltransferase
CORIN corin, serine peptidase
CRHR2 corticotropin releasing hormone receptor 2
CTH cystathionine gamma-lyase
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
DRD5 dopamine receptor D5
ELN elastin
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSTL3 follistatin-like 3 (secreted glycoprotein)
GUCA2B guanylate cyclase activator 2B (uroguanylin)
HRAS Harvey rat sarcoma viral oncogene homolog
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
IRS1 insulin receptor substrate 1
KCNK6 potassium channel, two pore domain subfamily K, member 6
KRAS Kirsten rat sarcoma viral oncogene homolog
MPV17 MpV17 mitochondrial inner membrane protein
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPA natriuretic peptide A
NPR1 natriuretic peptide receptor 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PDC phosducin
PNMT phenylethanolamine N-methyltransferase
PPARG peroxisome proliferator-activated receptor gamma
PRKG1 protein kinase, cGMP-dependent, type I
SCNN1B sodium channel, non voltage gated 1 beta subunit
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18
TAL1 T-cell acute lymphocytic leukemia 1
TLR5 toll-like receptor 5
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WNK4 WNK lysine deficient protein kinase 4