hypersensitivity Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system. (Gene Ontology, GO_0002524)
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Genes

128 genes co-occuring with the biological term hypersensitivity in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE angiotensin I converting enzyme
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
AGER advanced glycosylation end product-specific receptor
AGTR2 angiotensin II receptor, type 2
AHR aryl hydrocarbon receptor
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
APP amyloid beta (A4) precursor protein
AR androgen receptor
AREG amphiregulin
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATF7 activating transcription factor 7
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
C6 complement component 6
CALCA calcitonin-related polypeptide alpha
CASP1 caspase 1, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL17 chemokine (C-C motif) ligand 17
CCL2 chemokine (C-C motif) ligand 2
CCR3 chemokine (C-C motif) receptor 3
CD14 CD14 molecule
CD47 CD47 molecule
CD8A CD8a molecule
CD8B CD8b molecule
COL26A1 collagen, type XXVI, alpha 1
COMT catechol-O-methyltransferase
COTL1 coactosin-like F-actin binding protein 1
CRHR1 corticotropin releasing hormone receptor 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTSK cathepsin K
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYSLTR1 cysteinyl leukotriene receptor 1
CYSLTR2 cysteinyl leukotriene receptor 2
EGR2 early growth response 2
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ESR1 estrogen receptor 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FPR2 formyl peptide receptor 2
FZD3 frizzled class receptor 3
GATA3 GATA binding protein 3
GCG glucagon
GCLC glutamate-cysteine ligase, catalytic subunit
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSK3B glycogen synthase kinase 3 beta
HCP5 HLA complex P5 (non-protein coding)
HDAC6 histone deacetylase 6
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOMER1 homer scaffolding protein 1
HSPA1A heat shock 70kDa protein 1A
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNG interferon, gamma
IGF1R insulin-like growth factor 1 receptor
IL12A interleukin 12A
IL17A interleukin 17A
IL18 interleukin 18
IL18BP interleukin 18 binding protein
IL31 interleukin 31
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
JAK2 Janus kinase 2
LDHA lactate dehydrogenase A
LIPE lipase, hormone-sensitive
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MICA MHC class I polypeptide-related sequence A
MPL MPL proto-oncogene, thrombopoietin receptor
MYD88 myeloid differentiation primary response 88
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PDCD1 programmed cell death 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLN polymerase (DNA directed) nu
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAD9A RAD9 homolog A (S. pombe)
RBBP8 retinoblastoma binding protein 8
RGS7BP regulator of G-protein signaling 7 binding protein
S1PR1 sphingosine-1-phosphate receptor 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBXAS1 thromboxane A synthase 1 (platelet)
TEK TEK tyrosine kinase, endothelial
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBS4 thrombospondin 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TPH1 tryptophan hydroxylase 1
TPSAB1 tryptase alpha/beta 1
TPT1 tumor protein, translationally-controlled 1
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TYK2 tyrosine kinase 2
UBE2B ubiquitin-conjugating enzyme E2B
USP18 ubiquitin specific peptidase 18
WRN Werner syndrome, RecQ helicase-like
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound