hypersensitivity reaction type ii disease Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues. (Human Disease Ontology, DOID_417)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:417
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Genes

725 genes associated with the disease hypersensitivity reaction type ii disease in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 2.83059
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 2.1372
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.1154
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 2.10422
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.88168
LUC7L LUC7-like (S. cerevisiae) 1.74809
C6ORF10 chromosome 6 open reading frame 10 1.73572
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.68822
TMPRSS6 transmembrane protease, serine 6 1.6622
MPP1 membrane protein, palmitoylated 1, 55kDa 1.63837
MSH5 mutS homolog 5 1.62915
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 1.60875
CFB complement factor B 1.60101
EHMT2 euchromatic histone-lysine N-methyltransferase 2 1.59046
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 1.55738
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 1.51254
PRRC2A proline-rich coiled-coil 2A 1.50714
GPANK1 G patch domain and ankyrin repeats 1 1.49634
TCF19 transcription factor 19 1.4752
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.44134
LAMB1 laminin, beta 1 1.42467
STK19 serine/threonine kinase 19 1.39396
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 1.39396
STAT4 signal transducer and activator of transcription 4 1.39315
BTNL2 butyrophilin-like 2 1.38606
NOTCH4 notch 4 1.38276
SLC38A10 solute carrier family 38, member 10 1.37327
FADS1 fatty acid desaturase 1 1.35834
RECK reversion-inducing-cysteine-rich protein with kazal motifs 1.35834
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 1.34719
SEPHS1 selenophosphate synthetase 1 1.31635
C2 complement component 2 1.30078
DPCR1 diffuse panbronchiolitis critical region 1 1.29651
ALDH1L2 aldehyde dehydrogenase 1 family, member L2 1.28906
RYR2 ryanodine receptor 2 (cardiac) 1.26953
MX1 MX dynamin-like GTPase 1 1.26953
SNORD48 small nucleolar RNA, C/D box 48 1.26953
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.25477
LRRTM4 leucine rich repeat transmembrane neuronal 4 1.25477
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 1.25477
CEP131 centrosomal protein 131kDa 1.25477
EGF epidermal growth factor 1.25477
FOXP2 forkhead box P2 1.24194
ARMC3 armadillo repeat containing 3 1.23034
RELL1 RELT-like 1 1.23034
SNTG1 syntrophin, gamma 1 1.23034
MUC22 mucin 22 1.22776
CLRN1-AS1 CLRN1 antisense RNA 1 1.21996
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 1.21996
AAA1 aortic aneurysm, familial abdominal 1 1.21019
ITGA11 integrin, alpha 11 1.19386
ARID5B AT rich interactive domain 5B (MRF1-like) 1.19386
KCNIP4 Kv channel interacting protein 4 1.19386
ELL2 elongation factor, RNA polymerase II, 2 1.19386
EPAS1 endothelial PAS domain protein 1 1.19386
TRIM5 tripartite motif containing 5 1.19386
SGCZ sarcoglycan, zeta 1.19386
STAB2 stabilin 2 1.19386
VAV2 vav 2 guanine nucleotide exchange factor 1.19386
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 1.16426
SLIT1 slit homolog 1 (Drosophila) 1.14463
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 1.14463
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 1.14463
SHISA6 shisa family member 6 1.14463
PARVB parvin, beta 1.14463
COL19A1 collagen, type XIX, alpha 1 1.14463
SMYD1 SET and MYND domain containing 1 1.14463
CPNE8 copine VIII 1.14463
EPB41L2 erythrocyte membrane protein band 4.1-like 2 1.14463
LOC286190 1.14463
TMEM132D transmembrane protein 132D 1.14463
SMYD2 SET and MYND domain containing 2 1.14463
CCDC40 coiled-coil domain containing 40 1.14463
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.14463
SBF1 SET binding factor 1 1.14463
HFE hemochromatosis 1.14463
GLI3 GLI family zinc finger 3 1.14463
LOC729911 1.14463
POU6F2 POU class 6 homeobox 2 1.10764
CNTNAP5 contactin associated protein-like 5 1.10764
LINC00469 long intergenic non-protein coding RNA 469 1.10764
EYS eyes shut homolog (Drosophila) 1.10764
SKI SKI proto-oncogene 1.10764
PTPRT protein tyrosine phosphatase, receptor type, T 1.10764
SORBS1 sorbin and SH3 domain containing 1 1.10764
PRKG1 protein kinase, cGMP-dependent, type I 1.10764
CTIF CBP80/20-dependent translation initiation factor 1.10764
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase 1.10764
ANGPT1 angiopoietin 1 1.10764
MDC1 mediator of DNA-damage checkpoint 1 1.10764
TRIM6 tripartite motif containing 6 1.10764
ELMO1 engulfment and cell motility 1 1.10088
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 1.09769
PLD5 phospholipase D family, member 5 1.07599
AUTS2 autism susceptibility candidate 2 1.07599
ETV6 ets variant 6 1.07599
LBR lamin B receptor 1.07599
CDK18 cyclin-dependent kinase 18 1.07599
TOPAZ1 testis and ovary specific PAZ domain containing 1 1.07599
AGR2 anterior gradient 2 1.07599
GFRA1 GDNF family receptor alpha 1 1.07599
REC114 REC114 meiotic recombination protein 1.07599
ZNF423 zinc finger protein 423 1.07599
ABI3 ABI family, member 3 1.07599
CDH13 cadherin 13 1.07599
JAKMIP1 janus kinase and microtubule interacting protein 1 1.07599
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 1.07599
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 1.07599
LINGO2 leucine rich repeat and Ig domain containing 2 1.07599
CHD2 chromodomain helicase DNA binding protein 2 1.07599
NRG3 neuregulin 3 1.07599
LOC100505940 1.07599
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 1.04846
ANO2 anoctamin 2, calcium activated chloride channel 1.04846
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 1.04846
LRRC4C leucine rich repeat containing 4C 1.04846
ACO1 aconitase 1, soluble 1.04846
FRY furry homolog (Drosophila) 1.04846
SCUBE1 signal peptide, CUB domain, EGF-like 1 1.04846
PARK2 parkin RBR E3 ubiquitin protein ligase 1.04846
LBP lipopolysaccharide binding protein 1.04846
FMNL2 formin-like 2 1.04846
CYFIP2 cytoplasmic FMR1 interacting protein 2 1.04846
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 1.04846
CNTN1 contactin 1 1.04846
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 1.04846
TMEM182 transmembrane protein 182 1.04846
ZNF804B zinc finger protein 804B 1.04846
SLC26A3 solute carrier family 26 (anion exchanger), member 3 1.04846
GPM6A glycoprotein M6A 1.04846
CSMD1 CUB and Sushi multiple domains 1 1.04846
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 1.04846
TRIM31 tripartite motif containing 31 1.02645
MPRIP myosin phosphatase Rho interacting protein 1.02476
EFCAB6 EF-hand calcium binding domain 6 1.02476
FOXP1 forkhead box P1 1.02476
LOC100132735 uncharacterized LOC100132735 1.02476
CNN1 calponin 1, basic, smooth muscle 1.02476
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 1.02476
GRM3 glutamate receptor, metabotropic 3 1.02476
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 1.02476
USH2A Usher syndrome 2A (autosomal recessive, mild) 1.02476
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 1.02476
MTSS1 metastasis suppressor 1 1.02476
LPP LIM domain containing preferred translocation partner in lipoma 1.01734
VARS2 valyl-tRNA synthetase 2, mitochondrial 1.01164
C6ORF15 chromosome 6 open reading frame 15 1.00876
PLEKHA7 pleckstrin homology domain containing, family A member 7 1.00596
DNAH10 dynein, axonemal, heavy chain 10 1.00407
SYT9 synaptotagmin IX 1.00407
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 1.00407
PTGER3 prostaglandin E receptor 3 (subtype EP3) 1.00407
BEND7 BEN domain containing 7 1.00407
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.00407
GPR158 G protein-coupled receptor 158 1.00407
CEP170B centrosomal protein 170B 1.00407
DNAL4 dynein, axonemal, light chain 4 1.00407
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 1.00407
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa 1.00407
SLC31A1 solute carrier family 31 (copper transporter), member 1 0.986376
TBC1D14 TBC1 domain family, member 14 0.986376
ATF6 activating transcription factor 6 0.986376
TMEM255B transmembrane protein 255B 0.986376
DNER delta/notch-like EGF repeat containing 0.986376
PAPD4 PAP associated domain containing 4 0.986376
TTLL2 tubulin tyrosine ligase-like family member 2 0.986376
MON2 MON2 homolog (S. cerevisiae) 0.986376
HUNK hormonally up-regulated Neu-associated kinase 0.986376
SYNGR1 synaptogyrin 1 0.986376
TEK TEK tyrosine kinase, endothelial 0.986376
DNASE2B deoxyribonuclease II beta 0.986376
IGFBP7 insulin-like growth factor binding protein 7 0.986376
CNTNAP2 contactin associated protein-like 2 0.986376
HRH1 histamine receptor H1 0.986376
LOC100132731 uncharacterized LOC100132731 0.986376
CADPS Ca++-dependent secretion activator 0.986376
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.986376
LOC643962 uncharacterized LOC643962 0.986376
PROX2 prospero homeobox 2 0.986376
PRKD1 protein kinase D1 0.986376
HLA-DRA major histocompatibility complex, class II, DR alpha 0.978232
PTGFR prostaglandin F receptor (FP) 0.971169
UMODL1 uromodulin-like 1 0.971169
MEF2BNB-MEF2B MEF2BNB-MEF2B readthrough 0.971169
MEGF10 multiple EGF-like-domains 10 0.971169
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.971169
LRP1B low density lipoprotein receptor-related protein 1B 0.971169
PLCH1 phospholipase C, eta 1 0.971169
EMC9 ER membrane protein complex subunit 9 0.971169
PNOC prepronociceptin 0.971169
RAB3C RAB3C, member RAS oncogene family 0.971169
DOCK2 dedicator of cytokinesis 2 0.971169
PRICKLE2 prickle homolog 2 (Drosophila) 0.971169
PTPRR protein tyrosine phosphatase, receptor type, R 0.971169
MUC21 mucin 21, cell surface associated 0.971039
PSORS1C1 psoriasis susceptibility 1 candidate 1 0.958747
POU5F1 POU class 5 homeobox 1 0.958365
RNF39 ring finger protein 39 0.905664
HCG18 HLA complex group 18 (non-protein coding) 0.893807
ZNRD1 zinc ribbon domain containing 1 0.886948
TNPO3 transportin 3 0.87169
PSORS1C3 psoriasis susceptibility 1 candidate 3 (non-protein coding) 0.849303
HCG9 HLA complex group 9 (non-protein coding) 0.834659
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.821463
TP53 tumor protein p53 0.755798
CARD11 caspase recruitment domain family, member 11 0.753174
CCSER1 coiled-coil serine-rich protein 1 0.748112
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 0.734059
GTF2I general transcription factor IIi 0.691509
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.686457
ANKRD6 ankyrin repeat domain 6 0.670943
MICB MHC class I polypeptide-related sequence B 0.657853
GPSM3 G-protein signaling modulator 3 0.615901
SLC44A4 solute carrier family 44, member 4 0.614036
TNXB tenascin XB 0.595622
ATXN2 ataxin 2 0.486713
IL12RB2 interleukin 12 receptor, beta 2 0.480993
IL2RA interleukin 2 receptor, alpha 0.480885
C1QTNF6 C1q and tumor necrosis factor related protein 6 0.479788
TNIP1 TNFAIP3 interacting protein 1 0.475783
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.472535
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.453623
KIAA1109 KIAA1109 0.442982
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.438494
CD247 CD247 molecule 0.437404
SH2B3 SH2B adaptor protein 3 0.436281
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.432792
LOC100506023 uncharacterized LOC100506023 0.43137
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.424932
TSHR thyroid stimulating hormone receptor 0.420523
ZMIZ1 zinc finger, MIZ-type containing 1 0.413903
CCHCR1 coiled-coil alpha-helical rod protein 1 0.412953
RNASET2 ribonuclease T2 0.412439
TG thyroglobulin 0.407437
MACROD2 MACRO domain containing 2 0.405737
PXK PX domain containing serine/threonine kinase 0.401658
KIAA0319L KIAA0319-like 0.396727
UBASH3A ubiquitin associated and SH3 domain containing A 0.394445
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.384562
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.380747
PTPRK protein tyrosine phosphatase, receptor type, K 0.377031
CLEC16A C-type lectin domain family 16, member A 0.375673
ARHGAP31 Rho GTPase activating protein 31 0.37522
SLAMF6 SLAM family member 6 0.374418
TYR tyrosinase 0.374418
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.369237
ICA1 islet cell autoantigen 1, 69kDa 0.365837
TMEM39A transmembrane protein 39A 0.365431
GPR19 G protein-coupled receptor 19 0.361059
C10ORF11 chromosome 10 open reading frame 11 0.357462
PHRF1 PHD and ring finger domains 1 0.351774
CD80 CD80 molecule 0.351595
JAZF1 JAZF zinc finger 1 0.350197
PUS10 pseudouridylate synthase 10 0.349846
YDJC YdjC homolog (bacterial) 0.347998
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.345773
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.345705
HLA-J major histocompatibility complex, class I, J (pseudogene) 0.342457
TAGAP T-cell activation RhoGTPase activating protein 0.340329
ANKRD55 ankyrin repeat domain 55 0.338182
RERE arginine-glutamic acid dipeptide (RE) repeats 0.335504
SOX5 SRY (sex determining region Y)-box 5 0.333579
BLK BLK proto-oncogene, Src family tyrosine kinase 0.330854
IKZF4 IKAROS family zinc finger 4 (Eos) 0.327529
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 0.327529
SAMD9L sterile alpha motif domain containing 9-like 0.32597
TRAF1 TNF receptor-associated factor 1 0.32597
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 0.324317
ATG5 autophagy related 5 0.322734
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.320977
FCRL3 Fc receptor-like 3 0.316011
FANCA Fanconi anemia, complementation group A 0.316011
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 0.316011
C5ORF30 chromosome 5 open reading frame 30 0.314868
AVEN apoptosis, caspase activation inhibitor 0.314009
LINC00305 long intergenic non-protein coding RNA 305 0.311544
RPGRIP1L RPGRIP1-like 0.309271
GRB2 growth factor receptor-bound protein 2 0.308141
UHRF1BP1 UHRF1 binding protein 1 0.306141
RPL3 ribosomal protein L3 0.305437
CLCA1 chloride channel accessory 1 0.30542
BANP BTG3 associated nuclear protein 0.303828
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.301051
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.299809
BBS5 Bardet-Biedl syndrome 5 0.298458
LAMC2 laminin, gamma 2 0.298102
EXOC3L4 exocyst complex component 3-like 4 0.296506
GRK4 G protein-coupled receptor kinase 4 0.296021
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.294414
PTPN2 protein tyrosine phosphatase, non-receptor type 2 0.294414
MMEL1 membrane metallo-endopeptidase-like 1 0.293861
WDFY4 WDFY family member 4 0.292002
UPK1B uroplakin 1B 0.291872
DPH2 DPH2 homolog (S. cerevisiae) 0.29145
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.291193
STPG2 sperm-tail PG-rich repeat containing 2 0.29104
TTC7A tetratricopeptide repeat domain 7A 0.290643
C6ORF106 chromosome 6 open reading frame 106 0.290451
RHPN2 rhophilin, Rho GTPase binding protein 2 0.289291
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.289115
PDE4B phosphodiesterase 4B, cAMP-specific 0.288183
CCR6 chemokine (C-C motif) receptor 6 0.286587
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.28546
ANKRD44 ankyrin repeat domain 44 0.285146
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 0.284561
RAD51B RAD51 paralog B 0.284561
RSBN1 round spermatid basic protein 1 0.284377
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.282936
XKR6 XK, Kell blood group complex subunit-related family, member 6 0.282693
NTM neurotrimin 0.282131
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.28157
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.281159
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 0.281159
OPCML opioid binding protein/cell adhesion molecule-like 0.278994
CNTN5 contactin 5 0.26819
CNTN4 contactin 4 0.266705
MOG myelin oligodendrocyte glycoprotein 0.266038
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 0.265165
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 0.262749
IL7R interleukin 7 receptor 0.261395
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.261099
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.260786
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 0.260395
CEP128 centrosomal protein 128kDa 0.259714
FAM167A-AS1 FAM167A antisense RNA 1 0.259465
MOB3B MOB kinase activator 3B 0.258439
EGFL8 EGF-like-domain, multiple 8 0.258242
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 0.257667
SPRED2 sprouty-related, EVH1 domain containing 2 0.256982
LRRC18 leucine rich repeat containing 18 0.256294
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.254027
UNC5C unc-5 homolog C (C. elegans) 0.253729
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.246733
BTN2A1 butyrophilin, subfamily 2, member A1 0.245727
IRF4 interferon regulatory factor 4 0.24557
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.2446
ICOSLG inducible T-cell co-stimulator ligand 0.2446
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.2446
DENND1B DENN/MADD domain containing 1B 0.244284
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 0.243809
AGER advanced glycosylation end product-specific receptor 0.241987
CD40 CD40 molecule, TNF receptor superfamily member 5 0.241518
SLC16A12 solute carrier family 16, member 12 0.240021
ATAT1 alpha tubulin acetyltransferase 1 0.236062
LYN LYN proto-oncogene, Src family tyrosine kinase 0.235565
IRF5 interferon regulatory factor 5 0.235565
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.235238
ICOS inducible T-cell co-stimulator 0.234938
PLEK pleckstrin 0.232278
AFF1 AF4/FMR2 family, member 1 0.232041
HCG22 HLA complex group 22 0.231996
SLIT3 slit homolog 3 (Drosophila) 0.231416
DOK6 docking protein 6 0.230915
ELF1 E74-like factor 1 (ets domain transcription factor) 0.230051
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 0.229042
PRDM16 PR domain containing 16 0.228955
FCRL1 Fc receptor-like 1 0.22887
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.22829
TRIM15 tripartite motif containing 15 0.227974
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.226803
KALRN kalirin, RhoGEF kinase 0.226099
KIF5A kinesin family member 5A 0.224946
CREBL2 cAMP responsive element binding protein-like 2 0.223395
PLCL2 phospholipase C-like 2 0.223395
HIP1 huntingtin interacting protein 1 0.223395
MED1 mediator complex subunit 1 0.222065
C1ORF106 chromosome 1 open reading frame 106 0.220902
TMEM187 transmembrane protein 187 0.220545
CLDN10 claudin 10 0.219707
AKAP2 A kinase (PRKA) anchor protein 2 0.21968
NPAS3 neuronal PAS domain protein 3 0.219282
PRICKLE1 prickle homolog 1 (Drosophila) 0.217572
COL17A1 collagen, type XVII, alpha 1 0.21691
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.21684
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.21684
LOC100288310 uncharacterized LOC100288310 0.216315
TRIM26 tripartite motif containing 26 0.216249
NEU1 sialidase 1 (lysosomal sialidase) 0.216183
TP63 tumor protein p63 0.215861
APOM apolipoprotein M 0.215673
FAM107A family with sequence similarity 107, member A 0.21553
ZFP36L1 ZFP36 ring finger protein-like 1 0.215329
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.21245
ARMC9 armadillo repeat containing 9 0.211454
TNF tumor necrosis factor 0.210382
SMOC2 SPARC related modular calcium binding 2 0.209294
TICAM1 toll-like receptor adaptor molecule 1 0.209294
NFIA nuclear factor I/A 0.208323
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 0.207615
CDK12 cyclin-dependent kinase 12 0.207447
SDK1 sidekick cell adhesion molecule 1 0.207281
MALRD1 MAM and LDL receptor class A domain containing 1 0.20557
FGFR1OP FGFR1 oncogene partner 0.205435
HSPA1L heat shock 70kDa protein 1-like 0.204133
APOE apolipoprotein E 0.202896
FRMD4B FERM domain containing 4B 0.20199
NELFE negative elongation factor complex member E 0.200253
GLB1 galactosidase, beta 1 0.200253
FBXL20 F-box and leucine-rich repeat protein 20 0.200253
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 0.199277
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.198666
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.198058
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 0.197003
PAX3 paired box 3 0.196245
GRIK1 glutamate receptor, ionotropic, kainate 1 0.195466
STX17 syntaxin 17 0.195244
SLA Src-like-adaptor 0.193947
MANBA mannosidase, beta A, lysosomal 0.19325
MYNN myoneurin 0.193074
ZSCAN26 zinc finger and SCAN domain containing 26 0.192806
ZNF112 zinc finger protein 112 0.192363
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.19067
IFI16 interferon, gamma-inducible protein 16 0.188537
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.186891
GRB10 growth factor receptor-bound protein 10 0.1864
WNT3 wingless-type MMTV integration site family, member 3 0.1864
CCDC88B coiled-coil domain containing 88B 0.185404
DLG2 discs, large homolog 2 (Drosophila) 0.182865
CD5L CD5 molecule-like 0.181585
LBH limb bud and heart development 0.180716
MYO16 myosin XVI 0.179828
TPTE transmembrane phosphatase with tensin homology 0.179828
LEF1 lymphoid enhancer-binding factor 1 0.179828
ITK IL2-inducible T-cell kinase 0.179781
CD28 CD28 molecule 0.179504
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 0.179414
APOLD1 apolipoprotein L domain containing 1 0.178313
AUH AU RNA binding protein/enoyl-CoA hydratase 0.178234
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.177548
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.177013
NXPH1 neurexophilin 1 0.176842
NTNG2 netrin G2 0.176029
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.176029
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.176029
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 0.176029
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.175457
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.175283
ALPK2 alpha-kinase 2 0.174077
RUNX3 runt-related transcription factor 3 0.17383
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.173354
NEK6 NIMA-related kinase 6 0.17317
ANXA6 annexin A6 0.17206
CPVL carboxypeptidase, vitellogenic-like 0.171738
MTTP microsomal triglyceride transfer protein 0.171158
EVA1A eva-1 homolog A (C. elegans) 0.171158
MICA MHC class I polypeptide-related sequence A 0.170414
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.170267
IQSEC3 IQ motif and Sec7 domain 3 0.17008
FCRL2 Fc receptor-like 2 0.169897
LY6G6C lymphocyte antigen 6 complex, locus G6C 0.169697
ZNF217 zinc finger protein 217 0.169213
MAPT microtubule-associated protein tau 0.169175
KLK2 kallikrein-related peptidase 2 0.169099
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 0.169099
DSTN destrin (actin depolymerizing factor) 0.169099
ZSCAN31 zinc finger and SCAN domain containing 31 0.16884
ALPK1 alpha-kinase 1 0.168062
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.167775
NEGR1 neuronal growth regulator 1 0.167367
OR4A15 olfactory receptor, family 4, subfamily A, member 15 0.167367
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 0.167367
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.167367
HYDIN HYDIN, axonemal central pair apparatus protein 0.167367
COLEC12 collectin sub-family member 12 0.167303
TMC2 transmembrane channel-like 2 0.165872
STK32B serine/threonine kinase 32B 0.165872
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.165872
HSPA1B heat shock 70kDa protein 1B 0.165678
PGBD1 piggyBac transposable element derived 1 0.165623
TGFBR3 transforming growth factor, beta receptor III 0.165528
ACOX1 acyl-CoA oxidase 1, palmitoyl 0.164707
STARD13 StAR-related lipid transfer (START) domain containing 13 0.164373
CDH18 cadherin 18, type 2 0.162949
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 0.162737
DYSF dysferlin 0.16253
PRKCZ protein kinase C, zeta 0.162226
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 0.161643
SRCIN1 SRC kinase signaling inhibitor 1 0.161455
THSD4 thrombospondin, type I, domain containing 4 0.16109
DCBLD1 discoidin, CUB and LCCL domain containing 1 0.160649
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.160478
PLXNA4 plexin A4 0.158055
SMAD3 SMAD family member 3 0.157854
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.157854
CALD1 caldesmon 1 0.157854
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 0.1569
LINC00466 long intergenic non-protein coding RNA 466 0.156483
DGKQ diacylglycerol kinase, theta 110kDa 0.155803
IL18RAP interleukin 18 receptor accessory protein 0.155478
FNDC3B fibronectin type III domain containing 3B 0.155478
RBMS3 RNA binding motif, single stranded interacting protein 3 0.155425
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.155268
PUM1 pumilio RNA-binding family member 1 0.154908
NUP98 nucleoporin 98kDa 0.154708
TRAF3 TNF receptor-associated factor 3 0.154708
CIB4 calcium and integrin binding family member 4 0.154561
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.153537
DTNBP1 dystrobrevin binding protein 1 0.153318
LOC284395 uncharacterized LOC284395 0.153318
SPATA5 spermatogenesis associated 5 0.152727
PVT1 Pvt1 oncogene (non-protein coding) 0.152564
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.152564
PTCHD4 patched domain containing 4 0.152363
LACTB lactamase, beta 0.152089
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.152089
SRBD1 S1 RNA binding domain 1 0.152012
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 0.151897
TSPAN11 tetraspanin 11 0.150679
MTCH1 mitochondrial carrier 1 0.150645
ITPK1 inositol-tetrakisphosphate 1-kinase 0.150281
VWA7 von Willebrand factor A domain containing 7 0.150023
RYR3 ryanodine receptor 3 0.149991
WBSCR17 Williams-Beuren syndrome chromosome region 17 0.149928
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.149376
POU2F1 POU class 2 homeobox 1 0.149376
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 0.149257
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.149228
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.149198
VAV1 vav 1 guanine nucleotide exchange factor 0.149169
GSDMB gasdermin B 0.148794
FOXD3 forkhead box D3 0.148351
RGS1 regulator of G-protein signaling 1 0.148351
MAML3 mastermind-like 3 (Drosophila) 0.14772
ARHGAP44 Rho GTPase activating protein 44 0.147619
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.14732
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.147077
BCRP2 breakpoint cluster region pseudogene 2 0.14691
FAM159A family with sequence similarity 159, member A 0.146516
RORA RAR-related orphan receptor A 0.146516
TSPAN18 tetraspanin 18 0.146291
LTF lactotransferrin 0.146291
WWOX WW domain containing oxidoreductase 0.146269
TIPRL TOR signaling pathway regulator 0.146136
DSC3 desmocollin 3 0.145834
FERMT1 fermitin family member 1 0.145644
HIC2 hypermethylated in cancer 2 0.145437
TASP1 taspase, threonine aspartase, 1 0.145213
BTN3A2 butyrophilin, subfamily 3, member A2 0.145054
CCDC91 coiled-coil domain containing 91 0.144609
CLYBL citrate lyase beta like 0.144366
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.14431
DNAH8 dynein, axonemal, heavy chain 8 0.144255
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.144255
PGM1 phosphoglucomutase 1 0.14402
ZPBP2 zona pellucida binding protein 2 0.143913
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.14372
SFSWAP splicing factor, suppressor of white-apricot family 0.143361
WISP1 WNT1 inducible signaling pathway protein 1 0.143294
STAC SH3 and cysteine rich domain 0.143244
RTKN2 rhotekin 2 0.14308
BCL2 B-cell CLL/lymphoma 2 0.142934
PRH1-PRR4 PRH1-PRR4 readthrough 0.142869
THEMIS thymocyte selection associated 0.142585
KIFAP3 kinesin-associated protein 3 0.142009
DOCK4 dedicator of cytokinesis 4 0.141863
KCNK10 potassium channel, two pore domain subfamily K, member 10 0.141591
PCDH11Y protocadherin 11 Y-linked 0.141576
SNED1 sushi, nidogen and EGF-like domains 1 0.141548
ADGRL2 adhesion G protein-coupled receptor L2 0.141478
CSMD3 CUB and Sushi multiple domains 3 0.141367
TSPAN16 tetraspanin 16 0.141147
IRAK2 interleukin-1 receptor-associated kinase 2 0.141053
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0.140893
NOL10 nucleolar protein 10 0.140801
ZNF677 zinc finger protein 677 0.140658
RIN2 Ras and Rab interactor 2 0.140542
CHODL chondrolectin 0.140516
LOH12CR1 loss of heterozygosity, 12, chromosomal region 1 0.14039
GHSR growth hormone secretagogue receptor 0.140377
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 0.140365
POLN polymerase (DNA directed) nu 0.14024
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 0.140227
LCT lactase 0.140104
C1QB complement component 1, q subcomponent, B chain 0.139862
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.139862
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.139779
NTF3 neurotrophin 3 0.139743
SUSD3 sushi domain containing 3 0.139532
CADPS2 Ca++-dependent secretion activator 2 0.139292
FAM69C family with sequence similarity 69, member C 0.139292
FBXO32 F-box protein 32 0.139269
OPHN1 oligophrenin 1 0.139112
HPGDS hematopoietic prostaglandin D synthase 0.139079
MYO5A myosin VA (heavy chain 12, myoxin) 0.138925
ALG9 ALG9, alpha-1,2-mannosyltransferase 0.138838
VAV3 vav 3 guanine nucleotide exchange factor 0.138816
ZNF496 zinc finger protein 496 0.138613
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.138169
KIAA1644 KIAA1644 0.137903
CPM carboxypeptidase M 0.137387
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 0.137261
LRRK2 leucine-rich repeat kinase 2 0.137261
FFAR4 free fatty acid receptor 4 0.137136
WT1 Wilms tumor 1 0.136889
NCR2 natural cytotoxicity triggering receptor 2 0.136889
NELL1 NEL-like 1 (chicken) 0.136768
NCS1 neuronal calcium sensor 1 0.13641
PDE8A phosphodiesterase 8A 0.136177
LPAR1 lysophosphatidic acid receptor 1 0.136061
SHISA9 shisa family member 9 0.136061
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 0.136061
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.13561
AVL9 AVL9 homolog (S. cerevisiase) 0.134961
FAM24A family with sequence similarity 24, member A 0.134961
MEGF11 multiple EGF-like-domains 11 0.134961
LAMA2 laminin, alpha 2 0.134443
WSCD1 WSC domain containing 1 0.134443
DNAH12 dynein, axonemal, heavy chain 12 0.134142
ZNF667 zinc finger protein 667 0.133945
HPSE2 heparanase 2 (inactive) 0.133559
KANK4 KN motif and ankyrin repeat domains 4 0.133464
LIN7A lin-7 homolog A (C. elegans) 0.133092
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 0.13273
VIM vimentin 0.132553
LRRC20 leucine rich repeat containing 20 0.132119
CORO1C coronin, actin binding protein, 1C 0.132119
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.132119
PLCL1 phospholipase C-like 1 0.132119
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.132119
UROC1 urocanate hydratase 1 0.131866
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.131454
NUF2 NUF2, NDC80 kinetochore complex component 0.131293
PKN2 protein kinase N2 0.131134
NTNG1 netrin G1 0.130592
NKAIN3 Na+/K+ transporting ATPase interacting 3 0.130516
L3MBTL4 l(3)mbt-like 4 (Drosophila) 0.130144
PPARA peroxisome proliferator-activated receptor alpha 0.129925
MAMLD1 mastermind-like domain containing 1 0.129782
IVD isovaleryl-CoA dehydrogenase 0.129782
ATXN1 ataxin 1 0.129782
BMPR1B bone morphogenetic protein receptor, type IB 0.129499
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase 0.129429
TGFB2 transforming growth factor, beta 2 0.129154
ANK1 ankyrin 1, erythrocytic 0.129086
ROR1 receptor tyrosine kinase-like orphan receptor 1 0.129086
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4 0.128885
UBE2Q2P1 ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 1 0.128818
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.128818
PIEZO2 piezo-type mechanosensitive ion channel component 2 0.128555
VSIG2 V-set and immunoglobulin domain containing 2 0.128426
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene) 0.128426
PVR poliovirus receptor 0.128426
BID BH3 interacting domain death agonist 0.128298
RNF144A ring finger protein 144A 0.127675
RGS10 regulator of G-protein signaling 10 0.127197
TGM3 transglutaminase 3 0.127139
GRIK4 glutamate receptor, ionotropic, kainate 4 0.127023
PRR5L proline rich 5 like 0.12685
KIAA1217 KIAA1217 0.126736
LOC100506274 uncharacterized LOC100506274 0.126624
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.126624
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) 0.126624
OR51E2 olfactory receptor, family 51, subfamily E, member 2 0.126346
E2F3 E2F transcription factor 3 0.126346
ADI1 acireductone dioxygenase 1 0.126074
SOX2-OT SOX2 overlapping transcript 0.125967
PDPN podoplanin 0.125914
IFIH1 interferon induced with helicase C domain 1 0.125808
VWC2L von Willebrand factor C domain containing protein 2-like 0.125444
CAPN14 calpain 14 0.125291
METTL18 methyltransferase like 18 0.12519
CAGE1 cancer antigen 1 0.12509
BARX2 BARX homeobox 2 0.12504
IP6K3 inositol hexakisphosphate kinase 3 0.12504
DNAH14 dynein, axonemal, heavy chain 14 0.124745
FAM135B family with sequence similarity 135, member B 0.124697
PRUNE2 prune homolog 2 (Drosophila) 0.124697
VSTM4 V-set and transmembrane domain containing 4 0.124552
ADCY5 adenylate cyclase 5 0.124552
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 0.124505
ADRA1B adrenoceptor alpha 1B 0.124362
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 0.124362
TFIP11 tuftelin interacting protein 11 0.124222
STARD3 StAR-related lipid transfer (START) domain containing 3 0.124082
CSN1S2BP casein alpha s2-like B, pseudogene 0.124082
DGKG diacylglycerol kinase, gamma 90kDa 0.124082
NUAK1 NUAK family, SNF1-like kinase, 1 0.124036
KIAA0319 KIAA0319 0.124036
SRRD SRR1 domain containing 0.12399
NRXN3 neurexin 3 0.123899
MAGED1 melanoma antigen family D1 0.123763
IGSF23 immunoglobulin superfamily, member 23 0.123763
ZNRD1-AS1 ZNRD1 antisense RNA 1 0.123629
SLC39A11 solute carrier family 39, member 11 0.12319
EDA ectodysplasin A 0.12319
SH3GLB2 SH3-domain GRB2-like endophilin B2 0.122766
CAMKMT calmodulin-lysine N-methyltransferase 0.121572
MIER1 mesoderm induction early response 1, transcriptional regulator 0.121308
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.121197
IDO2 indoleamine 2,3-dioxygenase 2 0.121197
PHTF1 putative homeodomain transcription factor 1 0.120478
GNA14 guanine nucleotide binding protein (G protein), alpha 14 0.120478
TOX thymocyte selection-associated high mobility group box 0.120133
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 0.120032
KIAA1549 KIAA1549 0.119797
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.119151
SIL1 SIL1 nucleotide exchange factor 0.11912
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.11884
TBX5 T-box 5 0.118536
NKX2-3 NK2 homeobox 3 0.118536
PDE4D phosphodiesterase 4D, cAMP-specific 0.118239
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 0.117948
SCAMP5 secretory carrier membrane protein 5 0.117948
SYT1 synaptotagmin I 0.117806
VAC14 Vac14 homolog (S. cerevisiae) 0.117387
INADL InaD-like (Drosophila) 0.117387
BCL2L15 BCL2-like 15 0.117387
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.117196
TCAP titin-cap 0.117115
FGD5 FYVE, RhoGEF and PH domain containing 5 0.117115
CD226 CD226 molecule 0.117115
MIR99AHG mir-99a-let-7c cluster host gene 0.116588
PRDM10 PR domain containing 10 0.116033
NRROS negative regulator of reactive oxygen species 0.115861
COX20 COX20 cytochrome c oxidase assembly factor 0.115548
ADAD1 adenosine deaminase domain containing 1 (testis-specific) 0.115359
CIPC CLOCK-interacting pacemaker 0.114944
PRAM1 PML-RARA regulated adaptor molecule 1 0.114921
ACSF3 acyl-CoA synthetase family member 3 0.114303
DCN decorin 0.114217
RNF213 ring finger protein 213 0.112934
RSPO4 R-spondin 4 0.112274
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 0.109019
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta 0.108491
IRF2BPL interferon regulatory factor 2 binding protein-like 0.108464