hypersensitivity reaction type ii disease Gene Set

Dataset DISEASES Curated Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues. (Human Disease Ontology, DOID_417)
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Genes

39 genes involed in the disease hypersensitivity reaction type ii disease from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.

Symbol Name
BANK1 B-cell scaffold protein with ankyrin repeats 1
BLK BLK proto-oncogene, Src family tyrosine kinase
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
CD40 CD40 molecule, TNF receptor superfamily member 5
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DNASE1 deoxyribonuclease I
DNASE1L3 deoxyribonuclease I-like 3
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IL2RA interleukin 2 receptor, alpha
IRF5 interferon regulatory factor 5
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
LTK leukocyte receptor tyrosine kinase
MBP myelin basic protein
MEFV Mediterranean fever
NCF2 neutrophil cytosolic factor 2
PDCD1 programmed cell death 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
SAA1 serum amyloid A1
SCGB3A2 secretoglobin, family 3A, member 2
STAT4 signal transducer and activator of transcription 4
TG thyroglobulin
TLR5 toll-like receptor 5
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TREX1 three prime repair exonuclease 1
TSHR thyroid stimulating hormone receptor
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6