hydrocortisone-6684 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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193 genes differentially expressed following the hydrocortisone-6684 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP5 A kinase (PRKA) anchor protein 5
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ANKRD6 ankyrin repeat domain 6
ANXA2P1 annexin A2 pseudogene 1
AQP4 aquaporin 4
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BET1L Bet1 golgi vesicular membrane trafficking protein-like
CHMP6 charged multivesicular body protein 6
CLCN4 chloride channel, voltage-sensitive 4
CLCN7 chloride channel, voltage-sensitive 7
CNPY4 canopy FGF signaling regulator 4
COL10A1 collagen, type X, alpha 1
COL1A2 collagen, type I, alpha 2
COL6A1 collagen, type VI, alpha 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRLF1 cytokine receptor-like factor 1
CTSF cathepsin F
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIO3 deiodinase, iodothyronine, type III
DTNB dystrobrevin, beta
DUSP1 dual specificity phosphatase 1
EDA ectodysplasin A
EDN3 endothelin 3
EFCAB11 EF-hand calcium binding domain 11
EFNA3 ephrin-A3
EFS embryonal Fyn-associated substrate
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAAH fatty acid amide hydrolase
FGFR1 fibroblast growth factor receptor 1
FOXL1 forkhead box L1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GLS2 glutaminase 2 (liver, mitochondrial)
GPR22 G protein-coupled receptor 22
GRM8 glutamate receptor, metabotropic 8
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTPBP1 GTP binding protein 1
HESX1 HESX homeobox 1
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IGLJ3 immunoglobulin lambda joining 3
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KIDINS220 kinase D-interacting substrate, 220kDa
LAMA2 laminin, alpha 2
LAMC2 laminin, gamma 2
LDB1 LIM domain binding 1
LIG3 ligase III, DNA, ATP-dependent
MAU2 MAU2 sister chromatid cohesion factor
MDM4 MDM4, p53 regulator
MFAP3L microfibrillar-associated protein 3-like
MGC2889 uncharacterized protein MGC2889
MT1X metallothionein 1X
NCAM1 neural cell adhesion molecule 1
NNMT nicotinamide N-methyltransferase
NOV nephroblastoma overexpressed
NRP2 neuropilin 2
NUDC nudC nuclear distribution protein
OCA2 oculocutaneous albinism II
OLFM4 olfactomedin 4
PCOLCE procollagen C-endopeptidase enhancer
PER1 period circadian clock 1
PEX3 peroxisomal biogenesis factor 3
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKNOX2 PBX/knotted 1 homeobox 2
PLAT plasminogen activator, tissue
PLXNB3 plexin B3
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RARG retinoic acid receptor, gamma
RHOT2 ras homolog family member T2
RUNX1 runt-related transcription factor 1
SCGB2A1 secretoglobin, family 2A, member 1
SCN1B sodium channel, voltage gated, type I beta subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SMAD9 SMAD family member 9
SNAI2 snail family zinc finger 2
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SOX5 SRY (sex determining region Y)-box 5
SRSF5 serine/arginine-rich splicing factor 5
SSX3 synovial sarcoma, X breakpoint 3
SUSD5 sushi domain containing 5
TBKBP1 TBK1 binding protein 1
TBXA2R thromboxane A2 receptor
TCP11L1 t-complex 11, testis-specific-like 1
THBS1 thrombospondin 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMOD1 tropomodulin 1
TNK2 tyrosine kinase, non-receptor, 2
TSC22D3 TSC22 domain family, member 3
TTC38 tetratricopeptide repeat domain 38
TUBA3C tubulin, alpha 3c
ZNF280A zinc finger protein 280A
ZNF407 zinc finger protein 407
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACKR3 atypical chemokine receptor 3
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL14 ADP-ribosylation factor-like 14
ATAD5 ATPase family, AAA domain containing 5
ATAT1 alpha tubulin acetyltransferase 1
AURKC aurora kinase C
BTC betacellulin
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF93 chromosome 14 open reading frame 93
C19ORF54 chromosome 19 open reading frame 54
C1ORF54 chromosome 1 open reading frame 54
CCP110 centriolar coiled coil protein 110kDa
CD79A CD79a molecule, immunoglobulin-associated alpha
CDKL3 cyclin-dependent kinase-like 3
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRDL1 chordin-like 1
CIDEC cell death-inducing DFFA-like effector c
CLDN15 claudin 15
CXORF56 chromosome X open reading frame 56
DAGLA diacylglycerol lipase, alpha
DPF3 D4, zinc and double PHD fingers, family 3
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ELSPBP1 epididymal sperm binding protein 1
FAM184A family with sequence similarity 184, member A
FBXL7 F-box and leucine-rich repeat protein 7
FIG4 FIG4 phosphoinositide 5-phosphatase
FKBP10 FK506 binding protein 10, 65 kDa
GID4 GID complex subunit 4
GPNMB glycoprotein (transmembrane) nmb
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HIST1H1T histone cluster 1, H1t
HIST1H2AM histone cluster 1, H2am
HIST1H4C histone cluster 1, H4c
HMOX1 heme oxygenase 1
HOMER2 homer scaffolding protein 2
HOXA7 homeobox A7
HOXC8 homeobox C8
IER3IP1 immediate early response 3 interacting protein 1
IL2 interleukin 2
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KIAA0319L KIAA0319-like
KIAA1107 KIAA1107
KIAA1456 KIAA1456
KIRREL kin of IRRE like (Drosophila)
KLHL3 kelch-like family member 3
KPTN kaptin (actin binding protein)
KRT9 keratin 9, type I
LY6G5C lymphocyte antigen 6 complex, locus G5C
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD3 LY6/PLAUR domain containing 3
MAP9 microtubule-associated protein 9
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MFSD10 major facilitator superfamily domain containing 10
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPS18C mitochondrial ribosomal protein S18C
MUC3A mucin 3A, cell surface associated
NPM3 nucleophosmin/nucleoplasmin 3
NPY1R neuropeptide Y receptor Y1
NXPH4 neurexophilin 4
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PARM1 prostate androgen-regulated mucin-like protein 1
PDE8B phosphodiesterase 8B
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPT2 palmitoyl-protein thioesterase 2
PRF1 perforin 1 (pore forming protein)
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRPH peripherin
RAG2 recombination activating gene 2
SCG5 secretogranin V
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
STAC SH3 and cysteine rich domain
TAOK1 TAO kinase 1
TENM4 teneurin transmembrane protein 4
TM6SF1 transmembrane 6 superfamily member 1
TM7SF3 transmembrane 7 superfamily member 3
TMEM132A transmembrane protein 132A
TTC30A tetratricopeptide repeat domain 30A
TTF2 transcription termination factor, RNA polymerase II
WDR19 WD repeat domain 19
WDR62 WD repeat domain 62
ZNF442 zinc finger protein 442
ZNF770 zinc finger protein 770
ZNF85 zinc finger protein 85