hycanthone-4630 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the hycanthone-4630 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY9 adenylate cyclase 9
AKR1C2 aldo-keto reductase family 1, member C2
AOC2 amine oxidase, copper containing 2 (retina-specific)
AOC3 amine oxidase, copper containing 3
APOLD1 apolipoprotein L domain containing 1
ARHGAP35 Rho GTPase activating protein 35
ARL14 ADP-ribosylation factor-like 14
ARTN artemin
ATF5 activating transcription factor 5
B9D2 B9 protein domain 2
BCL2 B-cell CLL/lymphoma 2
C11ORF63 chromosome 11 open reading frame 63
C1ORF116 chromosome 1 open reading frame 116
C2CD2L C2CD2-like
CAMP cathelicidin antimicrobial peptide
CBX5 chromobox homolog 5
CCDC71 coiled-coil domain containing 71
CCDC85B coiled-coil domain containing 85B
CDC14A cell division cycle 14A
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CFAP69 cilia and flagella associated protein 69
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CRHR2 corticotropin releasing hormone receptor 2
CXCL2 chemokine (C-X-C motif) ligand 2
DAZL deleted in azoospermia-like
DCSTAMP dendrocyte expressed seven transmembrane protein
DENND3 DENN/MADD domain containing 3
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DIEXF digestive organ expansion factor homolog (zebrafish)
EGR1 early growth response 1
FAM102A family with sequence similarity 102, member A
GJA8 gap junction protein, alpha 8, 50kDa
GRM4 glutamate receptor, metabotropic 4
H3F3B H3 histone, family 3B (H3.3B)
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IL6 interleukin 6
JUNB jun B proto-oncogene
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KLF4 Kruppel-like factor 4 (gut)
LOC157562 uncharacterized LOC157562
LOXL3 lysyl oxidase-like 3
MMP11 matrix metallopeptidase 11
MMP9 matrix metallopeptidase 9
MTMR7 myotubularin related protein 7
MX1 MX dynamin-like GTPase 1
MYL10 myosin, light chain 10, regulatory
MYOZ2 myozenin 2
N4BP2L2 NEDD4 binding protein 2-like 2
NIPAL3 NIPA-like domain containing 3
NR2F6 nuclear receptor subfamily 2, group F, member 6
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRG1 neuregulin 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PAX2 paired box 2
PAX8 paired box 8
PDE4DIP phosphodiesterase 4D interacting protein
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RAD50 RAD50 homolog (S. cerevisiae)
RHO rhodopsin
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRAGD Ras-related GTP binding D
RS1 retinoschisin 1
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SETD1A SET domain containing 1A
SIRT4 sirtuin 4
SLC16A6 solute carrier family 16, member 6
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SNRK SNF related kinase
SOS2 son of sevenless homolog 2 (Drosophila)
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STON1 stonin 1
STS steroid sulfatase (microsomal), isozyme S
TACR1 tachykinin receptor 1
TAPBP TAP binding protein (tapasin)
TCF3 transcription factor 3
TGIF2 TGFB-induced factor homeobox 2
THSD7A thrombospondin, type I, domain containing 7A
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRAFD1 TRAF-type zinc finger domain containing 1
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TSC22D4 TSC22 domain family, member 4
VGF VGF nerve growth factor inducible
WDR62 WD repeat domain 62
XYLB xylulokinase homolog (H. influenzae)
ZBTB1 zinc finger and BTB domain containing 1
ZNF219 zinc finger protein 219
ZNF268 zinc finger protein 268
ZNF408 zinc finger protein 408
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ALG12 ALG12, alpha-1,6-mannosyltransferase
ASB7 ankyrin repeat and SOCS box containing 7
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BIN3 bridging integrator 3
C16ORF59 chromosome 16 open reading frame 59
CAPN15 calpain 15
CD72 CD72 molecule
CDH7 cadherin 7, type 2
CENPE centromere protein E, 312kDa
CHMP6 charged multivesicular body protein 6
CHRM3 cholinergic receptor, muscarinic 3
CINP cyclin-dependent kinase 2 interacting protein
CLCN5 chloride channel, voltage-sensitive 5
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTSF cathepsin F
DCAF13 DDB1 and CUL4 associated factor 13
DEF6 differentially expressed in FDCP 6 homolog (mouse)
EFNA3 ephrin-A3
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
FAM114A2 family with sequence similarity 114, member A2
FANCE Fanconi anemia, complementation group E
FILIP1L filamin A interacting protein 1-like
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GTF2I general transcription factor IIi
H1F0 H1 histone family, member 0
HAS2 hyaluronan synthase 2
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HMGA2 high mobility group AT-hook 2
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IL32 interleukin 32
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
KCTD20 potassium channel tetramerization domain containing 20
KLHL28 kelch-like family member 28
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT8P12 keratin 8 pseudogene 12
LINC00597 long intergenic non-protein coding RNA 597
LMNB1 lamin B1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAGEH1 melanoma antigen family H1
MAP3K7CL MAP3K7 C-terminal like
MBTPS2 membrane-bound transcription factor peptidase, site 2
MRPL41 mitochondrial ribosomal protein L41
MSL1 male-specific lethal 1 homolog (Drosophila)
MYO1F myosin IF
MYOZ1 myozenin 1
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NDP Norrie disease (pseudoglioma)
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NHEJ1 nonhomologous end-joining factor 1
NPPB natriuretic peptide B
NR1H4 nuclear receptor subfamily 1, group H, member 4
OLFM4 olfactomedin 4
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
OSMR oncostatin M receptor
PDE8B phosphodiesterase 8B
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PODXL2 podocalyxin-like 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRM2 protamine 2
PRPH peripherin
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTTG2 pituitary tumor-transforming 2
PWAR5 Prader Willi/Angelman region RNA 5
PYCRL pyrroline-5-carboxylate reductase-like
RSAD1 radical S-adenosyl methionine domain containing 1
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SOBP sine oculis binding protein homolog (Drosophila)
SP140L SP140 nuclear body protein-like
STAG3 stromal antigen 3
STEAP4 STEAP family member 4
SYTL2 synaptotagmin-like 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM209 transmembrane protein 209
TOM1 target of myb1 (chicken)
TRIM68 tripartite motif containing 68
TSNAXIP1 translin-associated factor X interacting protein 1
WDR33 WD repeat domain 33
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC3H3 zinc finger CCCH-type containing 3
ZFP30 ZFP30 zinc finger protein
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF215 zinc finger protein 215
ZNF227 zinc finger protein 227