homosalate-4533 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the homosalate-4533 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF4 AF4/FMR2 family, member 4
AGTR1 angiotensin II receptor, type 1
ANKRD7 ankyrin repeat domain 7
ATAD5 ATPase family, AAA domain containing 5
ATF7IP activating transcription factor 7 interacting protein
BAIAP3 BAI1-associated protein 3
BCL2 B-cell CLL/lymphoma 2
BGN biglycan
BTG2 BTG family, member 2
C10ORF10 chromosome 10 open reading frame 10
C14ORF79 chromosome 14 open reading frame 79
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASQ2 calsequestrin 2 (cardiac muscle)
CDK13 cyclin-dependent kinase 13
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDON cell adhesion associated, oncogene regulated
CHGA chromogranin A
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLCA2 chloride channel accessory 2
CLTA clathrin, light chain A
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CXCR2 chemokine (C-X-C motif) receptor 2
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DTNA dystrobrevin, alpha
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
FGF1 fibroblast growth factor 1 (acidic)
FLT1 fms-related tyrosine kinase 1
FYB FYN binding protein
GALR2 galanin receptor 2
GK glycerol kinase
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPNMB glycoprotein (transmembrane) nmb
GRAMD1C GRAM domain containing 1C
GVINP1 GTPase, very large interferon inducible pseudogene 1
HDAC11 histone deacetylase 11
HFE hemochromatosis
HNF1A HNF1 homeobox A
HOXB2 homeobox B2
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IMPG2 interphotoreceptor matrix proteoglycan 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KDM5B lysine (K)-specific demethylase 5B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT17 keratin 17, type I
LMOD1 leiomodin 1 (smooth muscle)
LOC157562 uncharacterized LOC157562
LOX lysyl oxidase
LRRN3 leucine rich repeat neuronal 3
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAGEB2 melanoma antigen family B2
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK8 mitogen-activated protein kinase 8
MATN3 matrilin 3
MEG3 maternally expressed 3 (non-protein coding)
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MPPE1 metallophosphoesterase 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NEBL nebulette
NRP1 neuropilin 1
ONECUT1 one cut homeobox 1
PDGFA platelet-derived growth factor alpha polypeptide
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHEX phosphate regulating endopeptidase homolog, X-linked
PKNOX1 PBX/knotted 1 homeobox 1
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PRKCA protein kinase C, alpha
RAB14 RAB14, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RBM26 RNA binding motif protein 26
RBM34 RNA binding motif protein 34
RHEB Ras homolog enriched in brain
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SARM1 sterile alpha and TIR motif containing 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SMCP sperm mitochondria-associated cysteine-rich protein
SOS2 son of sevenless homolog 2 (Drosophila)
SPON1 spondin 1, extracellular matrix protein
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK24 serine/threonine kinase 24
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
TM4SF4 transmembrane 4 L six family member 4
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
UBE3A ubiquitin protein ligase E3A
VGLL3 vestigial-like family member 3
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF639 zinc finger protein 639
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
AMDHD2 amidohydrolase domain containing 2
ANP32A-IT1 ANP32A intronic transcript 1
ANXA2P1 annexin A2 pseudogene 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
BAAT bile acid CoA:amino acid N-acyltransferase
C16ORF62 chromosome 16 open reading frame 62
C1S complement component 1, s subcomponent
C5ORF45 chromosome 5 open reading frame 45
CA5B carbonic anhydrase VB, mitochondrial
CDH10 cadherin 10, type 2 (T2-cadherin)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLEC2B C-type lectin domain family 2, member B
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPNE7 copine VII
DEPTOR DEP domain containing MTOR-interacting protein
DNAL4 dynein, axonemal, light chain 4
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ETNK2 ethanolamine kinase 2
FAM120C family with sequence similarity 120C
FAM53B family with sequence similarity 53, member B
FMO4 flavin containing monooxygenase 4
FOXN2 forkhead box N2
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1T histone cluster 1, H1t
HIST1H4D histone cluster 1, H4d
IGFLR1 IGF-like family receptor 1
INF2 inverted formin, FH2 and WH2 domain containing
INPPL1 inositol polyphosphate phosphatase-like 1
IQSEC2 IQ motif and Sec7 domain 2
IREB2 iron-responsive element binding protein 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPKA inositol-trisphosphate 3-kinase A
KIAA0319L KIAA0319-like
KLF3 Kruppel-like factor 3 (basic)
KRT4 keratin 4, type II
KRT8P12 keratin 8 pseudogene 12
LY6D lymphocyte antigen 6 complex, locus D
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAP1S microtubule-associated protein 1S
MAST3 microtubule associated serine/threonine kinase 3
MFGE8 milk fat globule-EGF factor 8 protein
MYL9 myosin, light chain 9, regulatory
NBEAL2 neurobeachin-like 2
NSD1 nuclear receptor binding SET domain protein 1
OSBP2 oxysterol binding protein 2
PDE12 phosphodiesterase 12
PID1 phosphotyrosine interaction domain containing 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PROSER1 proline and serine rich 1
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRSS53 protease, serine, 53
PTPRS protein tyrosine phosphatase, receptor type, S
RABL6 RAB, member RAS oncogene family-like 6
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM38 RNA binding motif protein 38
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOBTB2 Rho-related BTB domain containing 2
RIN1 Ras and Rab interactor 1
RNF122 ring finger protein 122
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPP25 ribonuclease P/MRP 25kDa subunit
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT6 sirtuin 6
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SMR3A submaxillary gland androgen regulated protein 3A
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
STARD3 StAR-related lipid transfer (START) domain containing 3
SYT17 synaptotagmin XVII
TBC1D12 TBC1 domain family, member 12
TBXAS1 thromboxane A synthase 1 (platelet)
TEP1 telomerase-associated protein 1
TGFBI transforming growth factor, beta-induced, 68kDa
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLN1 talin 1
TMSB15A thymosin beta 15a
TNRC6B trinucleotide repeat containing 6B
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TUBG2 tubulin, gamma 2
UGT8 UDP glycosyltransferase 8
ULK1 unc-51 like autophagy activating kinase 1
USB1 U6 snRNA biogenesis 1
VAT1 vesicle amine transport 1
VEZT vezatin, adherens junctions transmembrane protein
WNT10B wingless-type MMTV integration site family, member 10B
ZNF215 zinc finger protein 215
ZNF358 zinc finger protein 358
ZNF510 zinc finger protein 510
ZNF529 zinc finger protein 529