homosalate-4355 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the homosalate-4355 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
AASS aminoadipate-semialdehyde synthase
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADTRP androgen-dependent TFPI-regulating protein
AKAP5 A kinase (PRKA) anchor protein 5
AKAP6 A kinase (PRKA) anchor protein 6
APC adenomatous polyposis coli
ARHGAP26 Rho GTPase activating protein 26
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BTN3A1 butyrophilin, subfamily 3, member A1
C2 complement component 2
C5AR1 complement component 5a receptor 1
CD53 CD53 molecule
CD93 CD93 molecule
CDHR1 cadherin-related family member 1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEP295 centrosomal protein 295kDa
CEP41 centrosomal protein 41kDa
CHML choroideremia-like (Rab escort protein 2)
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CLDN16 claudin 16
CNTN1 contactin 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CTIF CBP80/20-dependent translation initiation factor
CTNS cystinosin, lysosomal cystine transporter
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EMC3 ER membrane protein complex subunit 3
FST follistatin
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FYB FYN binding protein
GDF5 growth differentiation factor 5
GLYAT glycine-N-acyltransferase
GPM6A glycoprotein M6A
GPR22 G protein-coupled receptor 22
GRM7 glutamate receptor, metabotropic 7
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HFE hemochromatosis
HIF3A hypoxia inducible factor 3, alpha subunit
HIPK2 homeodomain interacting protein kinase 2
HOXA11 homeobox A11
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KANK3 KN motif and ankyrin repeat domains 3
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA1109 KIAA1109
KRT8 keratin 8, type II
LAPTM5 lysosomal protein transmembrane 5
LCAT lecithin-cholesterol acyltransferase
LIPE lipase, hormone-sensitive
LOC79999 uncharacterized LOC79999
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LTBP4 latent transforming growth factor beta binding protein 4
MIER2 mesoderm induction early response 1, family member 2
MIIP migration and invasion inhibitory protein
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MVB12B multivesicular body subunit 12B
NPR1 natriuretic peptide receptor 1
NPTX2 neuronal pentraxin II
NR6A1 nuclear receptor subfamily 6, group A, member 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PI15 peptidase inhibitor 15
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLK3 polo-like kinase 3
PVT1 Pvt1 oncogene (non-protein coding)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RERE arginine-glutamic acid dipeptide (RE) repeats
RNF39 ring finger protein 39
RYR1 ryanodine receptor 1 (skeletal)
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SHOX2 short stature homeobox 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A30 solute carrier family 25, member 30
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNX13 sorting nexin 13
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAGLN3 transgelin 3
TCF25 transcription factor 25 (basic helix-loop-helix)
TDRD12 tudor domain containing 12
TENM4 teneurin transmembrane protein 4
TGFBR1 transforming growth factor, beta receptor 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNS1 tensin 1
TRAPPC9 trafficking protein particle complex 9
TRIM36 tripartite motif containing 36
TRPM3 transient receptor potential cation channel, subfamily M, member 3
USP22 ubiquitin specific peptidase 22
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
WIPF1 WAS/WASL interacting protein family, member 1
WRNIP1 Werner helicase interacting protein 1
XIST X inactive specific transcript (non-protein coding)
XYLB xylulokinase homolog (H. influenzae)
ZFP64 ZFP64 zinc finger protein

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
A4GALT alpha 1,4-galactosyltransferase
ABI3BP ABI family, member 3 (NESH) binding protein
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
AMH anti-Mullerian hormone
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
C14ORF79 chromosome 14 open reading frame 79
C1QTNF3 C1q and tumor necrosis factor related protein 3
C5AR2 complement component 5a receptor 2
CASC1 cancer susceptibility candidate 1
CCDC69 coiled-coil domain containing 69
CLSTN2 calsyntenin 2
CNPY4 canopy FGF signaling regulator 4
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRYGC crystallin, gamma C
CUZD1 CUB and zona pellucida-like domains 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DAGLA diacylglycerol lipase, alpha
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DLK2 delta-like 2 homolog (Drosophila)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DRD1 dopamine receptor D1
DSCAM Down syndrome cell adhesion molecule
ELP3 elongator acetyltransferase complex subunit 3
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FAAH fatty acid amide hydrolase
FAM110B family with sequence similarity 110, member B
FBXO2 F-box protein 2
FGF23 fibroblast growth factor 23
FSTL1 follistatin-like 1
GATA4 GATA binding protein 4
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH3 G patch domain containing 3
GPR157 G protein-coupled receptor 157
GSTP1 glutathione S-transferase pi 1
HAMP hepcidin antimicrobial peptide
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H2AI histone cluster 1, H2ai
HIST1H3B histone cluster 1, H3b
HOXC4 homeobox C4
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFI27 interferon, alpha-inducible protein 27
IGSF1 immunoglobulin superfamily, member 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KDM7A lysine (K)-specific demethylase 7A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KREMEN2 kringle containing transmembrane protein 2
KRT13 keratin 13, type I
LGALS9 lectin, galactoside-binding, soluble, 9
LPPR2 lipid phosphate phosphatase-related protein type 2
LRRC37A3 leucine rich repeat containing 37, member A3
LY6G6C lymphocyte antigen 6 complex, locus G6C
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
NNAT neuronatin
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OSMR oncostatin M receptor
PADI3 peptidyl arginine deiminase, type III
PARP3 poly (ADP-ribose) polymerase family, member 3
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE8B phosphodiesterase 8B
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLA2G3 phospholipase A2, group III
PLAC1 placenta-specific 1
PSCA prostate stem cell antigen
RNF2 ring finger protein 2
RPAP1 RNA polymerase II associated protein 1
SAYSD1 SAYSVFN motif domain containing 1
SCARA3 scavenger receptor class A, member 3
SCGB2A2 secretoglobin, family 2A, member 2
SDC3 syndecan 3
SELL selectin L
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIPA1 signal-induced proliferation-associated 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC46A3 solute carrier family 46, member 3
SPINK1 serine peptidase inhibitor, Kazal type 1
SPTBN2 spectrin, beta, non-erythrocytic 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TEX14 testis expressed 14
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM209 transmembrane protein 209
TSC22D4 TSC22 domain family, member 4
TSGA10 testis specific, 10
USP20 ubiquitin specific peptidase 20
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF205 zinc finger protein 205
ZNF862 zinc finger protein 862
ZSWIM1 zinc finger, SWIM-type containing 1