hodgkin's lymphoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A lymphoma that is marked by the presence of a type of cell called the Reed-Sternberg cell. (Human Disease Ontology, DOID_8567)
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Genes

364 genes co-occuring with the disease hodgkin's lymphoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 2.26376
PAX5 paired box 5 1.96989
GPR15 G protein-coupled receptor 15 1.88159
PDLIM7 PDZ and LIM domain 7 (enigma) 1.8724
HYLS1 hydrolethalus syndrome 1 1.71453
PAX2 paired box 2 1.70133
BCL6 B-cell CLL/lymphoma 6 1.66555
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 1.62873
KLHDC8B kelch domain containing 8B 1.54849
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 1.54407
HDAC10 histone deacetylase 10 1.54142
POU2AF1 POU class 2 associating factor 1 1.50667
CD4 CD4 molecule 1.42323
IRF4 interferon regulatory factor 4 1.39214
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.36902
ALK anaplastic lymphoma receptor tyrosine kinase 1.36466
CCL17 chemokine (C-C motif) ligand 17 1.35594
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 1.35202
MSC musculin 1.34897
HDAC11 histone deacetylase 11 1.32541
TRAF1 TNF receptor-associated factor 1 1.3241
CSNK1G3 casein kinase 1, gamma 3 1.22085
GJB2 gap junction protein, beta 2, 26kDa 1.20959
HDAC9 histone deacetylase 9 1.2031
JAK2 Janus kinase 2 1.1541
CARTPT CART prepropeptide 1.14348
CD34 CD34 molecule 1.13543
FSCN1 fascin actin-bundling protein 1 1.11141
FSCN3 fascin actin-bundling protein 3, testicular 1.09125
CD68 CD68 molecule 1.09083
PRDM1 PR domain containing 1, with ZNF domain 1.08244
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.08244
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.07866
FXYD5 FXYD domain containing ion transport regulator 5 1.0669
HDAC4 histone deacetylase 4 1.06396
FSCN2 fascin actin-bundling protein 2, retinal 1.06186
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.05681
HABP4 hyaluronan binding protein 4 1.02608
CD163 CD163 molecule 1.02144
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.02102
CD79A CD79a molecule, immunoglobulin-associated alpha 1.0206
B3GAT1 beta-1,3-glucuronyltransferase 1 1.00288
TP53 tumor protein p53 1.00035
CD40 CD40 molecule, TNF receptor superfamily member 5 0.987693
CSF3 colony stimulating factor 3 (granulocyte) 0.941611
CD19 CD19 molecule 0.920085
SH2D1A SH2 domain containing 1A 0.900335
CD5 CD5 molecule 0.893359
EBF1 early B-cell factor 1 0.891718
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.886799
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.882701
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.881472
IL13 interleukin 13 0.859362
SLC26A4 solute carrier family 26 (anion exchanger), member 4 0.848716
CCL22 chemokine (C-C motif) ligand 22 0.823308
DNER delta/notch-like EGF repeat containing 0.816745
KLHL2 kelch-like family member 2 0.815104
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 0.811821
CT45A1 cancer/testis antigen family 45, member A1 0.791311
LDHD lactate dehydrogenase D 0.785165
LGALS1 lectin, galactoside-binding, soluble, 1 0.777386
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.770844
GJB6 gap junction protein, beta 6, 30kDa 0.769618
MAGEA4 melanoma antigen family A4 0.767985
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.752898
GJB3 gap junction protein, beta 3, 31kDa 0.747204
GCSAM germinal center-associated, signaling and motility 0.736649
NCAM1 neural cell adhesion molecule 1 0.733406
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.729357
FEV FEV (ETS oncogene family) 0.720865
BCL3 B-cell CLL/lymphoma 3 0.716021
TRAF3 TNF receptor-associated factor 3 0.712796
FOXP3 forkhead box P3 0.708364
BCL2L1 BCL2-like 1 0.707961
HDAC8 histone deacetylase 8 0.70434
PLXNA1 plexin A1 0.701928
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.69751
CD79B CD79b molecule, immunoglobulin-associated beta 0.686291
BIRC3 baculoviral IAP repeat containing 3 0.685891
POU2F2 POU class 2 homeobox 2 0.685491
CXCL13 chemokine (C-X-C motif) ligand 13 0.680697
HLA-C major histocompatibility complex, class I, C 0.677105
MYH14 myosin, heavy chain 14, non-muscle 0.676706
SLC46A2 solute carrier family 46, member 2 0.668345
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.666358
IL2RA interleukin 2 receptor, alpha 0.663578
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.662387
NOTCH1 notch 1 0.661197
RYBP RING1 and YY1 binding protein 0.63907
IL26 interleukin 26 0.635528
TCF3 transcription factor 3 0.634349
DAPK2 death-associated protein kinase 2 0.634349
NUP153 nucleoporin 153kDa 0.626888
IGHV3-30 immunoglobulin heavy variable 3-30 0.604201
B2M beta-2-microglobulin 0.59913
RIT1 Ras-like without CAAX 1 0.590169
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.58939
CTSC cathepsin C 0.586665
CD40LG CD40 ligand 0.586665
ATM ATM serine/threonine kinase 0.58433
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 0.583941
HLA-A major histocompatibility complex, class I, A 0.582773
ALB albumin 0.575383
CXCL10 chemokine (C-X-C motif) ligand 10 0.570329
IL10 interleukin 10 0.569941
GSTT1 glutathione S-transferase theta 1 0.569552
GSTTP1 glutathione S-transferase theta pseudogene 1 0.569552
STAT1 signal transducer and activator of transcription 1, 91kDa 0.566443
JUNB jun B proto-oncogene 0.550911
FASLG Fas ligand (TNF superfamily, member 6) 0.550134
AMH anti-Mullerian hormone 0.545481
GATA3 GATA binding protein 3 0.545093
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 0.544318
STXBP2 syntaxin binding protein 2 0.542379
PRAME preferentially expressed antigen in melanoma 0.538893
SEC31A SEC31 homolog A (S. cerevisiae) 0.537731
ATL3 atlastin GTPase 3 0.537731
SYK spleen tyrosine kinase 0.537344
HIGD1A HIG1 hypoxia inducible domain family, member 1A 0.533088
DPYSL5 dihydropyrimidinase-like 5 0.527676
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.52536
MIR96 microRNA 96 0.517265
F10 coagulation factor X 0.514186
IGHV5-51 immunoglobulin heavy variable 5-51 0.513417
FOXO1 forkhead box O1 0.510344
PRF1 perforin 1 (pore forming protein) 0.507273
IL2 interleukin 2 0.507273
SDC1 syndecan 1 0.503441
AMPH amphiphysin 0.502292
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.497321
CHUK conserved helix-loop-helix ubiquitous kinase 0.497321
CD38 CD38 molecule 0.493122
TMC1 transmembrane channel-like 1 0.488169
COL11A2P1 collagen, type XI, alpha 2 pseudogene 1 0.487788
COL11A2 collagen, type XI, alpha 2 0.487788
TECTA tectorin alpha 0.480945
LYN LYN proto-oncogene, Src family tyrosine kinase 0.480945
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 0.478668
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.47753
AICDA activation-induced cytidine deaminase 0.474877
CD70 CD70 molecule 0.47374
PHYH phytanoyl-CoA 2-hydroxylase 0.467306
SCARA3 scavenger receptor class A, member 3 0.466928
PDCD1 programmed cell death 1 0.465038
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 0.46466
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.464283
IL6 interleukin 6 0.458241
PIDD1 p53-induced death domain protein 1 0.457109
BIRC5 baculoviral IAP repeat containing 5 0.45447
GNG7 guanine nucleotide binding protein (G protein), gamma 7 0.452962
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.452208
TPX2 TPX2, microtubule-associated 0.451831
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.446558
SKAP1 src kinase associated phosphoprotein 1 0.442795
CD28 CD28 molecule 0.442418
NPAT nuclear protein, ataxia-telangiectasia locus 0.435275
CXCL9 chemokine (C-X-C motif) ligand 9 0.434524
CYLD cylindromatosis (turban tumor syndrome) 0.43227
CCR3 chemokine (C-C motif) receptor 3 0.431519
IL9 interleukin 9 0.431144
GSTM1 glutathione S-transferase mu 1 0.430393
GIPC3 GIPC PDZ domain containing family, member 3 0.430393
CCND1 cyclin D1 0.429266
DOK4 docking protein 4 0.428891
CD22 CD22 molecule 0.426265
TBX21 T-box 21 0.425514
GRM1 glutamate receptor, metabotropic 1 0.424014
CCND2 cyclin D2 0.420641
CD7 CD7 molecule 0.419517
CCL5 chemokine (C-C motif) ligand 5 0.41727
GPSM2 G-protein signaling modulator 2 0.413527
HOMER3 homer scaffolding protein 3 0.412779
CSF1R colony stimulating factor 1 receptor 0.411283
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.410909
DERL3 derlin 3 0.410161
CCL13 chemokine (C-C motif) ligand 13 0.409787
BCL2 B-cell CLL/lymphoma 2 0.404557
BAG6 BCL2-associated athanogene 6 0.403064
NFE2L3 nuclear factor, erythroid 2-like 3 0.399707
CXCR5 chemokine (C-X-C motif) receptor 5 0.397843
MYO3A myosin IIIA 0.396725
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.392629
PTPRC protein tyrosine phosphatase, receptor type, C 0.392629
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.390025
ANAPC5 anaphase promoting complex subunit 5 0.388538
BLNK B-cell linker 0.388166
IGLV1-36 immunoglobulin lambda variable 1-36 0.386679
LIN52 lin-52 DREAM MuvB core complex component 0.385193
LIN37 lin-37 DREAM MuvB core complex component 0.383337
CCR7 chemokine (C-C motif) receptor 7 0.382966
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.38111
AUH AU RNA binding protein/enoyl-CoA hydratase 0.380739
ANKRD55 ankyrin repeat domain 55 0.377031
FIGLA folliculogenesis specific basic helix-loop-helix 0.373328
FOXD2 forkhead box D2 0.372958
DEXI Dexi homolog (mouse) 0.371477
TNK1 tyrosine kinase, non-receptor, 1 0.369258
IL9R interleukin 9 receptor 0.368518
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 0.357077
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.354868
TUBB2B tubulin, beta 2B class IIb 0.353395
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 0.353027
KIF22 kinesin family member 22 0.35082
VIM vimentin 0.35082
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.350452
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.349717
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.340906
CDKN2A cyclin-dependent kinase inhibitor 2A 0.338341
TBC1D24 TBC1 domain family, member 24 0.334315
TNF tumor necrosis factor 0.333218
PCGF2 polycomb group ring finger 2 0.331025
CIITA class II, major histocompatibility complex, transactivator 0.32774
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 0.32373
SOCS3 suppressor of cytokine signaling 3 0.323365
GSTP1 glutathione S-transferase pi 1 0.321181
ANXA5 annexin A5 0.318272
MNX1 motor neuron and pancreas homeobox 1 0.315729
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.315366
NCOA2 nuclear receptor coactivator 2 0.314278
LMO2 LIM domain only 2 (rhombotin-like 1) 0.313915
FADD Fas (TNFRSF6)-associated via death domain 0.313552
GBX2 gastrulation brain homeobox 2 0.305587
JAK3 Janus kinase 3 0.30342
DFNB59 deafness, autosomal recessive 59 0.300533
TFRC transferrin receptor 0.300173
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.297291
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.296571
LY75 lymphocyte antigen 75 0.291898
TRIM37 tripartite motif containing 37 0.291898
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.291898
SNAP23 synaptosomal-associated protein, 23kDa 0.290103
MIR183 microRNA 183 0.289744
HLA-G major histocompatibility complex, class I, G 0.286519
CMIP c-Maf inducing protein 0.284013
CD80 CD80 molecule 0.283655
RANGAP1 Ran GTPase activating protein 1 0.283297
NGFR nerve growth factor receptor 0.28294
SRSF9 serine/arginine-rich splicing factor 9 0.280439
STRCP1 stereocilin pseudogene 1 0.279367
STRC stereocilin 0.279367
CD52 CD52 molecule 0.275445
HIST1H1D histone cluster 1, H1d 0.274376
ITK IL2-inducible T-cell kinase 0.272953
IPO7 importin 7 0.272597
CD27 CD27 molecule 0.271886
CCNK cyclin K 0.271174
BAX BCL2-associated X protein 0.270108
DDR1 discoidin domain receptor tyrosine kinase 1 0.270108
ALPPL2 alkaline phosphatase, placental-like 2 0.268332
ALPP alkaline phosphatase, placental 0.267977
ALPL alkaline phosphatase, liver/bone/kidney 0.267267
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 0.263722
RNF2 ring finger protein 2 0.261952
CAMLG calcium modulating ligand 0.259124
FOXN3 forkhead box N3 0.25877
CD81 CD81 molecule 0.257358
HES7 hes family bHLH transcription factor 7 0.257358
DDR2 discoidin domain receptor tyrosine kinase 2 0.257005
THEM4 thioesterase superfamily member 4 0.256652
CD63 CD63 molecule 0.254888
IL7R interleukin 7 receptor 0.254888
PTPRK protein tyrosine phosphatase, receptor type, K 0.254183
CXCL12 chemokine (C-X-C motif) ligand 12 0.252422
TCL1A T-cell leukemia/lymphoma 1A 0.251366
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 0.247852
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.246448
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.243645
LAG3 lymphocyte-activation gene 3 0.242945
MIR17 microRNA 17 0.238752
TP63 tumor protein p63 0.238752
PNMA2 paraneoplastic Ma antigen 2 0.238054
TARP TCR gamma alternate reading frame protein 0.238054
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.23666
MICB MHC class I polypeptide-related sequence B 0.232142
XPO5 exportin 5 0.230063
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.226262
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.225917
VSIG4 V-set and immunoglobulin domain containing 4 0.221793
MST1R macrophage stimulating 1 receptor 0.221108
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.21974
TPP2 tripeptidyl peptidase II 0.217012
BIRC2 baculoviral IAP repeat containing 2 0.211934
CD99 CD99 molecule 0.211597
IL3RA interleukin 3 receptor, alpha (low affinity) 0.209248
LCK LCK proto-oncogene, Src family tyrosine kinase 0.208579
SYNJ1 synaptojanin 1 0.206248
NOG noggin 0.202618
FGR FGR proto-oncogene, Src family tyrosine kinase 0.200982
MYO15A myosin XVA 0.200331
HDAC2 histone deacetylase 2 0.200331
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.19742
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.195501
HOXB9 homeobox B9 0.194548
CDK9 cyclin-dependent kinase 9 0.192657
MMP9 matrix metallopeptidase 9 0.192031
MINA MYC induced nuclear antigen 0.191097
GRM5 glutamate receptor, metabotropic 5 0.189551
CD200 CD200 molecule 0.187415
CFLAR CASP8 and FADD-like apoptosis regulator 0.187415
POU4F3 POU class 4 homeobox 3 0.187415
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.186811
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.185313
CRP C-reactive protein, pentraxin-related 0.182086
TEN1 TEN1 CST complex subunit 0.181222
FOXP1 forkhead box P1 0.180652
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 0.17896
HIST1H1C histone cluster 1, H1c 0.178682
LGALS3 lectin, galactoside-binding, soluble, 3 0.178403
ZIC3 Zic family member 3 0.177851
CCR6 chemokine (C-C motif) receptor 6 0.176757
EYA4 EYA transcriptional coactivator and phosphatase 4 0.175947
IL4 interleukin 4 0.175947
HRAS Harvey rat sarcoma viral oncogene homolog 0.175679
FANCL Fanconi anemia, complementation group L 0.174881
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.173571
CIRBP cold inducible RNA binding protein 0.173057
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 0.172799
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.172544
NR1D1 nuclear receptor subfamily 1, group D, member 1 0.170054
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.169571
CYBB cytochrome b-245, beta polypeptide 0.167682
RPTOR regulatory associated protein of MTOR, complex 1 0.167682
MET MET proto-oncogene, receptor tyrosine kinase 0.166768
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.166544
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.166319
CD247 CD247 molecule 0.165874
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.165001
CDKN3 cyclin-dependent kinase inhibitor 3 0.164786
ADGRL4 adhesion G protein-coupled receptor L4 0.163938
ARHGAP32 Rho GTPase activating protein 32 0.163729
FYN FYN proto-oncogene, Src family tyrosine kinase 0.162908
ESRRB estrogen-related receptor beta 0.162707
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.161716
CCL3 chemokine (C-C motif) ligand 3 0.160203
CCL20 chemokine (C-C motif) ligand 20 0.159838
HBS1L HBS1-like translational GTPase 0.159302
IL5RA interleukin 5 receptor, alpha 0.159124
AKAP17A A kinase (PRKA) anchor protein 17A 0.158951
JUN jun proto-oncogene 0.158778
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.158605
DLEC1 deleted in lung and esophageal cancer 1 0.157765
EPX eosinophil peroxidase 0.146659
DFNB31 deafness, autosomal recessive 31 0.142546
OTOF otoferlin 0.141928
UCN urocortin 0.141793
POU3F4 POU class 3 homeobox 4 0.141765
MYO6 myosin VI 0.141717
ACSL1 acyl-CoA synthetase long-chain family member 1 0.141524
COCH cochlin 0.140873
S100A9 S100 calcium binding protein A9 0.140873
CLCN7 chloride channel, voltage-sensitive 7 0.140579
MAP9 microtubule-associated protein 9 0.139494
IL4R interleukin 4 receptor 0.139108
SIX1 SIX homeobox 1 0.137988
PTGDR2 prostaglandin D2 receptor 2 0.137871
NID1 nidogen 1 0.137762
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.134062
WFS1 Wolfram syndrome 1 (wolframin) 0.133342
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.133283
DMPK dystrophia myotonica-protein kinase 0.13166
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.130144
CNR1 cannabinoid receptor 1 (brain) 0.129334
FGF1 fibroblast growth factor 1 (acidic) 0.12105
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.117848