histiocytic lymphoma cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The most common aggressive form of non-Hodgkin lymphoma. It occurs in both diffuse and nodular form. The large cells may have cleaved and non-cleaved nuclei. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001738)
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Genes

204 proteins co-occuring with the tissue histiocytic lymphoma cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
PON2 paraoxonase 2 1.64106
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.48036
TNF tumor necrosis factor 1.42691
STX18 syntaxin 18 1.42691
SCARB1 scavenger receptor class B, member 1 1.31333
NOS2 nitric oxide synthase 2, inducible 1.27919
LAMP1 lysosomal-associated membrane protein 1 1.23093
APOE apolipoprotein E 1.20334
LPL lipoprotein lipase 1.19089
IL1B interleukin 1, beta 1.11686
LPA lipoprotein, Lp(a) 1.09164
IL6 interleukin 6 1.08987
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.05589
TLR4 toll-like receptor 4 1.04928
CEL carboxyl ester lipase 0.969388
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.947378
CD36 CD36 molecule (thrombospondin receptor) 0.938777
SCARB2 scavenger receptor class B, member 2 0.930621
CARD17 caspase recruitment domain family, member 17 0.920344
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.919488
RHPN1 rhophilin, Rho GTPase binding protein 1 0.90285
PON1 paraoxonase 1 0.901147
KLHL25 kelch-like family member 25 0.89732
MRC1 mannose receptor, C type 1 0.887133
FBXO9 F-box protein 9 0.871061
APOA1 apolipoprotein A-I 0.845805
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.840349
AP3M2 adaptor-related protein complex 3, mu 2 subunit 0.826942
IL1A interleukin 1, alpha 0.820666
HAMP hepcidin antimicrobial peptide 0.81983
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.817322
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.797708
PTBP2 polypyrimidine tract binding protein 2 0.774004
ANTXR1 anthrax toxin receptor 1 0.772759
APOB apolipoprotein B 0.74834
ACTA1 actin, alpha 1, skeletal muscle 0.740503
DOK2 docking protein 2, 56kDa 0.739678
IL10 interleukin 10 0.704355
TLR2 toll-like receptor 2 0.703127
ALB albumin 0.692902
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.688409
MYBBP1A MYB binding protein (P160) 1a 0.675765
FDPS farnesyl diphosphate synthase 0.670064
SP110 SP110 nuclear body protein 0.665182
MERTK MER proto-oncogene, tyrosine kinase 0.663555
ANXA5 annexin A5 0.652589
MYD88 myeloid differentiation primary response 88 0.650154
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.648127
JUN jun proto-oncogene 0.644074
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.641238
YEATS4 YEATS domain containing 4 0.634358
SOD2 superoxide dismutase 2, mitochondrial 0.633144
PLG plasminogen 0.623446
SSR1 signal sequence receptor, alpha 0.614167
ALOX5 arachidonate 5-lipoxygenase 0.613361
RAP1A RAP1A, member of RAS oncogene family 0.607319
PKN2 protein kinase N2 0.598469
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.590839
TLR3 toll-like receptor 3 0.580017
TFRC transferrin receptor 0.579216
CCL2 chemokine (C-C motif) ligand 2 0.562441
LYZ lysozyme 0.560449
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.553286
TPST1 tyrosylprotein sulfotransferase 1 0.550106
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.546136
CD86 CD86 molecule 0.522405
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.516497
LY96 lymphocyte antigen 96 0.516104
TLR9 toll-like receptor 9 0.515317
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.512957
PTBP1 polypyrimidine tract binding protein 1 0.50471
PARP1 poly (ADP-ribose) polymerase 1 0.497657
CAPN7 calpain 7 0.491791
LDLR low density lipoprotein receptor 0.490229
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.484376
FTH1 ferritin, heavy polypeptide 1 0.479312
CAT catalase 0.478145
SAA1 serum amyloid A1 0.475423
DDR1 discoidin domain receptor tyrosine kinase 1 0.472704
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.468436
STAT1 signal transducer and activator of transcription 1, 91kDa 0.465335
AHCYL2 adenosylhomocysteinase-like 2 0.463787
PLA2G1B phospholipase A2, group IB (pancreas) 0.459145
APOH apolipoprotein H (beta-2-glycoprotein I) 0.457987
HDAC11 histone deacetylase 11 0.454126
ICAM1 intercellular adhesion molecule 1 0.451428
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.449116
FYB FYN binding protein 0.445653
GSR glutathione reductase 0.438356
MAP2K2 mitogen-activated protein kinase kinase 2 0.437972
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 0.437205
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.434906
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.431077
ELANE elastase, neutrophil expressed 0.430312
TRIO trio Rho guanine nucleotide exchange factor 0.428401
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.425726
IPO7 importin 7 0.424199
MPO myeloperoxidase 0.421148
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 0.420766
GUK1 guanylate kinase 1 0.407453
CTSD cathepsin D 0.395709
AHCYL1 adenosylhomocysteinase-like 1 0.38552
CTSL cathepsin L 0.382508
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.379875
NQO2 NAD(P)H dehydrogenase, quinone 2 0.379123
TF transferrin 0.379123
BAX BCL2-associated X protein 0.37687
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.374993
XAGE1E X antigen family, member 1E 0.368624
FTL ferritin, light polypeptide 0.36825
MMP9 matrix metallopeptidase 9 0.362646
IL34 interleukin 34 0.362273
XAGE1B X antigen family, member 1B 0.359292
GPX5 glutathione peroxidase 5 0.358174
PCSK7 proprotein convertase subtilisin/kexin type 7 0.35743
GPX4 glutathione peroxidase 4 0.354455
AKAP5 A kinase (PRKA) anchor protein 5 0.354084
MAPK1 mitogen-activated protein kinase 1 0.354084
SAA2 serum amyloid A2 0.346668
CXCL8 chemokine (C-X-C motif) ligand 8 0.346298
GPX1 glutathione peroxidase 1 0.34334
ENGASE endo-beta-N-acetylglucosaminidase 0.342233
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.338914
COLEC12 collectin sub-family member 12 0.338177
FGR FGR proto-oncogene, Src family tyrosine kinase 0.337072
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 0.333763
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.333028
HMOX1 heme oxygenase 1 0.332294
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.32753
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.327164
IFNA1 interferon, alpha 1 0.326432
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.326067
NFE2 nuclear factor, erythroid 2 0.325701
ADA adenosine deaminase 0.320227
NEGR1 neuronal growth regulator 1 0.319863
TGFB1 transforming growth factor, beta 1 0.319498
ANTXR2 anthrax toxin receptor 2 0.317315
BRWD1 bromodomain and WD repeat domain containing 1 0.315861
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.314409
CETP cholesteryl ester transfer protein, plasma 0.31187
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.311507
SYK spleen tyrosine kinase 0.311145
IL4 interleukin 4 0.309335
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.306444
IREB2 iron-responsive element binding protein 2 0.303919
HIST3H2BB histone cluster 3, H2bb 0.302478
HIST2H2BF histone cluster 2, H2bf 0.302478
HIST1H2BH histone cluster 1, H2bh 0.301758
HIST1H2BD histone cluster 1, H2bd 0.301039
PLEC plectin 0.301039
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 0.300679
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 0.298524
HIST1H2BA histone cluster 1, H2ba 0.297089
PLCG1 phospholipase C, gamma 1 0.297089
IRAK2 interleukin-1 receptor-associated kinase 2 0.297089
IRAK1 interleukin-1 receptor-associated kinase 1 0.291008
ELOVL4 ELOVL fatty acid elongase 4 0.289582
PKD2L1 polycystic kidney disease 2-like 1 0.289226
CCDC130 coiled-coil domain containing 130 0.28887
CD80 CD80 molecule 0.287447
HIST1H2BF histone cluster 1, H2bf 0.284253
HIST1H2BC histone cluster 1, H2bc 0.284253
C3 complement component 3 0.283545
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.283191
CCL3 chemokine (C-C motif) ligand 3 0.281776
MAPK8 mitogen-activated protein kinase 8 0.28107
CERK ceramide kinase 0.275444
CPD carboxypeptidase D 0.270909
RGS1 regulator of G-protein signaling 1 0.270561
LYN LYN proto-oncogene, Src family tyrosine kinase 0.269174
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.268828
LIPA lipase A, lysosomal acid, cholesterol esterase 0.268137
CXCL10 chemokine (C-X-C motif) ligand 10 0.265038
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.264011
PRCP prolylcarboxypeptidase (angiotensinase C) 0.262304
FECH ferrochelatase 0.261624
ERP29 endoplasmic reticulum protein 29 0.256902
LAMP2 lysosomal-associated membrane protein 2 0.255234
LEPR leptin receptor 0.248683
HSPA4 heat shock 70kDa protein 4 0.248683
PRF1 perforin 1 (pore forming protein) 0.24486
IFNG interferon, gamma 0.244545
PCTP phosphatidylcholine transfer protein 0.243918
PDCD5 programmed cell death 5 0.241132
GUSB glucuronidase, beta 0.237216
STIP1 stress-induced phosphoprotein 1 0.235748
SH2D3A SH2 domain containing 3A 0.234302
SCARF1 scavenger receptor class F, member 1 0.233731
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.232039
SPINK5 serine peptidase inhibitor, Kazal type 5 0.229032
NOS3 nitric oxide synthase 3 (endothelial cell) 0.229032
CSK c-src tyrosine kinase 0.228497
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.227445
PTS 6-pyruvoyltetrahydropterin synthase 0.223177
IL10RA interleukin 10 receptor, alpha 0.220378
E2F5 E2F transcription factor 5, p130-binding 0.219928
MYDGF myeloid-derived growth factor 0.218398
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.217554
MSR1 macrophage scavenger receptor 1 0.216325
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.215534
NLRC4 NLR family, CARD domain containing 4 0.215341
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.21365
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.213471
PPARG peroxisome proliferator-activated receptor gamma 0.212761