hippo signaling Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1. (Gene Ontology, GO_0035329)
External Link http://amigo.geneontology.org/amigo/term/GO:0035329
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Genes

26 genes participating in the hippo signaling biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AMOT angiomotin
AMOTL1 angiomotin like 1
AMOTL2 angiomotin like 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
DCHS1 dachsous cadherin-related 1
DVL2 dishevelled segment polarity protein 2
FAT4 FAT atypical cadherin 4
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
MOB1A MOB kinase activator 1A
MOB1B MOB kinase activator 1B
NPHP4 nephronophthisis 4
SAV1 salvador family WW domain containing protein 1
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 TEA domain family member 2
TEAD3 TEA domain family member 3
TEAD4 TEA domain family member 4
TJP1 tight junction protein 1
TJP2 tight junction protein 2
WWC1 WW and C2 domain containing 1
WWTR1 WW domain containing transcription regulator 1
YAP1 Yes-associated protein 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon