heterotrimeric g-protein complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein. (Gene Ontology, GO_0005834)
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34 proteins localized to the heterotrimeric g-protein complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
GNG5 guanine nucleotide binding protein (G protein), gamma 5 0.663342
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.663342
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.663342
GNAS GNAS complex locus 0.663342
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.663342
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 0.663342
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.237908
GNG3 guanine nucleotide binding protein (G protein), gamma 3 0.237908
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 0.098109
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 0.098109
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.098109
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.098109
GNAT3 guanine nucleotide binding protein, alpha transducing 3 0.098109
GNG2 guanine nucleotide binding protein (G protein), gamma 2 0.098109
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.098109
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.098109
GNA14 guanine nucleotide binding protein (G protein), alpha 14 0.098109
GNA12 guanine nucleotide binding protein (G protein) alpha 12 0.098109
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.098109
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.098109
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.098109
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.098109
GNG13 guanine nucleotide binding protein (G protein), gamma 13 0.03318
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.03318
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.03318
RGS7 regulator of G-protein signaling 7 0.03318
RGS9 regulator of G-protein signaling 9 0.03318
RGS11 regulator of G-protein signaling 11 0.03318
GNG7 guanine nucleotide binding protein (G protein), gamma 7 0.03318
GNG4 guanine nucleotide binding protein (G protein), gamma 4 0.03318
GNG8 guanine nucleotide binding protein (G protein), gamma 8 0.03318
RGS6 regulator of G-protein signaling 6 0.03318
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.03318
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 0.03318