herpes simplex Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A viral infectious disease that results_in_formation_of lesions, located_in mouth, located_in face, located_in genitalia, or located_in hands, has_material_basis_in Human herpesvirus 1 or has_material_basis_in Human herpesvirus 2, which are transmitted_by direct contact with an active lesion or body fluid of an infected person. (Human Disease Ontology, DOID_8566)
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Genes

300 genes co-occuring with the disease herpes simplex in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.43358
GYPC glycophorin C (Gerbich blood group) 1.78263
UNC93B1 unc-93 homolog B1 (C. elegans) 1.78038
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 1.71818
CD4 CD4 molecule 1.67548
ADSS adenylosuccinate synthase 1.5326
TLR3 toll-like receptor 3 1.41139
NFU1 NFU1 iron-sulfur cluster scaffold 1.33676
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 1.24993
CD79A CD79a molecule, immunoglobulin-associated alpha 1.20699
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 1.20137
YY2 YY2 transcription factor 1.17335
IL2 interleukin 2 1.13712
GLB1 galactosidase, beta 1 1.09083
GUK1 guanylate kinase 1 1.06942
NBPF8 neuroblastoma breakpoint family, member 8 1.06732
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M 1.03662
ZNF35 zinc finger protein 35 1.0265
ATAD2 ATPase family, AAA domain containing 2 0.982636
GGTA1P glycoprotein, alpha-galactosyltransferase 1 pseudogene 0.9696
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 0.960797
INIP INTS3 and NABP interacting protein 0.951187
IFNA1 interferon, alpha 1 0.935385
MED25 mediator complex subunit 25 0.881472
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.863046
TRAF3 TNF receptor-associated factor 3 0.849126
TLR9 toll-like receptor 9 0.842573
C21ORF91 chromosome 21 open reading frame 91 0.840525
NBPF10 neuroblastoma breakpoint family, member 10 0.824538
DUT deoxyuridine triphosphatase 0.806898
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.799513
HVCN1 hydrogen voltage gated channel 1 0.787623
TTC39A tetratricopeptide repeat domain 39A 0.776977
TK1 thymidine kinase 1, soluble 0.772887
PNKP polynucleotide kinase 3'-phosphatase 0.76921
SRSF11 serine/arginine-rich splicing factor 11 0.768801
IRAK4 interleukin-1 receptor-associated kinase 4 0.765943
TNF tumor necrosis factor 0.757786
TRIT1 tRNA isopentenyltransferase 1 0.752085
IFNB1 interferon, beta 1, fibroblast 0.743547
PENK proenkephalin 0.713198
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.712796
DTYMK deoxythymidylate kinase (thymidylate kinase) 0.705144
APOE apolipoprotein E 0.693499
SUB1 SUB1 homolog (S. cerevisiae) 0.683892
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.666358
IRF3 interferon regulatory factor 3 0.66596
PICALM phosphatidylinositol binding clathrin assembly protein 0.659611
POU2F1 POU class 2 homeobox 1 0.653671
HLA-B major histocompatibility complex, class I, B 0.633563
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 0.621792
PTOV1 prostate tumor overexpressed 1 0.619442
RCOR1 REST corepressor 1 0.611229
TLR2 toll-like receptor 2 0.60303
MBP myelin basic protein 0.598351
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.595623
IFNA6 interferon, alpha 6 0.58433
FCHSD2 FCH and double SH3 domains 2 0.578494
FLG2 filaggrin family member 2 0.578494
IL12RB1 interleukin 12 receptor, beta 1 0.576161
ERVW-1 endogenous retrovirus group W, member 1 0.575383
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.573828
TBK1 TANK-binding kinase 1 0.573439
ENY2 enhancer of yellow 2 homolog (Drosophila) 0.571107
EIF3M eukaryotic translation initiation factor 3, subunit M 0.56722
EXTL3 exostosin-like glycosyltransferase 3 0.558285
B3GAT1 beta-1,3-glucuronyltransferase 1 0.558285
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted 0.554791
ALB albumin 0.548583
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 0.540442
IL6 interleukin 6 0.540055
CCL5 chemokine (C-C motif) ligand 5 0.536183
KDM1A lysine (K)-specific demethylase 1A 0.535022
ZBTB14 zinc finger and BTB domain containing 14 0.533475
STAT1 signal transducer and activator of transcription 1, 91kDa 0.532701
OAT ornithine aminotransferase 0.531928
LEMD1 LEM domain containing 1 0.516879
POU3F4 POU class 3 homeobox 4 0.514186
POLI polymerase (DNA directed) iota 0.509576
GH2 growth hormone 2 0.50689
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.50459
IGF2-AS IGF2 antisense RNA 0.503441
FBXO7 F-box protein 7 0.503058
KPNA3 karyopherin alpha 3 (importin alpha 4) 0.500379
GUSB glucuronidase, beta 0.498085
IPO5 importin 5 0.491597
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 0.490454
EZR ezrin 0.485885
TMPO thymopoietin 0.485125
CARTPT CART prepropeptide 0.480945
MED15 mediator complex subunit 15 0.479047
KLK12 kallikrein-related peptidase 12 0.476014
FER fer (fps/fes related) tyrosine kinase 0.471468
C8ORF4 chromosome 8 open reading frame 4 0.467306
CXCL10 chemokine (C-X-C motif) ligand 10 0.464283
MYD88 myeloid differentiation primary response 88 0.462394
FLG filaggrin 0.458619
TLR7 toll-like receptor 7 0.458241
CCL3 chemokine (C-C motif) ligand 3 0.455978
CALD1 caldesmon 1 0.448817
IFNGR1 interferon gamma receptor 1 0.444676
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.44129
IRF2 interferon regulatory factor 2 0.440162
LIM2 lens intrinsic membrane protein 2, 19kDa 0.427765
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.427765
POU2F2 POU class 2 homeobox 2 0.427015
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.420266
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 0.419892
CD80 CD80 molecule 0.418394
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 0.415398
HLA-C major histocompatibility complex, class I, C 0.409787
B2M beta-2-microglobulin 0.403438
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.395235
NELFCD negative elongation factor complex member C/D 0.390769
ZNF222 zinc finger protein 222 0.388166
CALB1 calbindin 1, 28kDa 0.387051
TYK2 tyrosine kinase 2 0.386308
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.382223
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 0.37555
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.373698
LTF lactotransferrin 0.372587
PI3 peptidase inhibitor 3, skin-derived 0.372587
MPLKIP M-phase specific PLK1 interacting protein 0.372217
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.371477
CXCL9 chemokine (C-X-C motif) ligand 9 0.369258
LGALS4 lectin, galactoside-binding, soluble, 4 0.368888
MED12 mediator complex subunit 12 0.365932
CPE carboxypeptidase E 0.363347
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 0.35892
HCFC1 host cell factor C1 0.357814
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.357814
PTPRU protein tyrosine phosphatase, receptor type, U 0.356709
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.353027
TPP2 tripeptidyl peptidase II 0.352291
MAGEE1 melanoma antigen family E1 0.350084
DEFA3 defensin, alpha 3, neutrophil-specific 0.348981
RGPD3 RANBP2-like and GRIP domain containing 3 0.348246
TGOLN2 trans-golgi network protein 2 0.347511
HOXA2 homeobox A2 0.344941
IL3RA interleukin 3 receptor, alpha (low affinity) 0.34384
CH25H cholesterol 25-hydroxylase 0.343473
UNG uracil-DNA glycosylase 0.342372
RRM1 ribonucleotide reductase M1 0.342006
IL10 interleukin 10 0.340906
INSM1 insulinoma-associated 1 0.336144
IL7 interleukin 7 0.334681
KLRC2 killer cell lectin-like receptor subfamily C, member 2 0.331025
ADAM2 ADAM metallopeptidase domain 2 0.324458
IL15 interleukin 15 0.32009
IFNG interferon, gamma 0.317182
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.316819
CD52 CD52 molecule 0.312827
H2AFY H2A histone family, member Y 0.312102
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 0.311377
FRK fyn-related Src family tyrosine kinase 0.310652
FICD FIC domain containing 0.30848
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.308118
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.302337
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.300533
IFNA2 interferon, alpha 2 0.293694
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.291539
C5AR2 complement component 5a receptor 2 0.28831
TGM3 transglutaminase 3 0.285444
NCR1 natural cytotoxicity triggering receptor 1 0.285444
SHKBP1 SH3KBP1 binding protein 1 0.284728
TSLP thymic stromal lymphopoietin 0.283297
HIST1H1B histone cluster 1, H1b 0.282225
GH1 growth hormone 1 0.27687
ZBTB32 zinc finger and BTB domain containing 32 0.274732
DSC1 desmocollin 1 0.274376
TP53 tumor protein p53 0.272953
A2M alpha-2-macroglobulin 0.271174
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.270819
PVR poliovirus receptor 0.270108
GGCT gamma-glutamylcyclotransferase 0.268687
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.268687
NGF nerve growth factor (beta polypeptide) 0.267977
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.266558
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 0.265849
IRF1 interferon regulatory factor 1 0.265494
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 0.264431
HLA-A major histocompatibility complex, class I, A 0.264077
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.262306
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.261245
GNAT3 guanine nucleotide binding protein, alpha transducing 3 0.258064
HIST1H1A histone cluster 1, H1a 0.256652
SCNN1D sodium channel, non voltage gated 1 delta subunit 0.253831
CABIN1 calcineurin binding protein 1 0.248554
ERV3-1 endogenous retrovirus group 3, member 1 0.243295
TBX21 T-box 21 0.241895
KLRG1 killer cell lectin-like receptor subfamily G, member 1 0.241546
TAT tyrosine aminotransferase 0.238752
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.238752
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.238403
CD209 CD209 molecule 0.235616
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.23492
DPP6 dipeptidyl-peptidase 6 0.23492
EOMES eomesodermin 0.232836
DLX3 distal-less homeobox 3 0.231102
MBL2 mannose-binding lectin (protein C) 2, soluble 0.230063
FANCB Fanconi anemia, complementation group B 0.230063
DCTD dCMP deaminase 0.229716
BIRC6 baculoviral IAP repeat containing 6 0.229024
FSTL1 follistatin-like 1 0.227988
CRP C-reactive protein, pentraxin-related 0.224884
JUND jun D proto-oncogene 0.224196
CDA cytidine deaminase 0.222822
FGF4 fibroblast growth factor 4 0.218374
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.217012
ARTN artemin 0.217012
SENP1 SUMO1/sentrin specific peptidase 1 0.216332
RANBP2 RAN binding protein 2 0.212608
TPH2 tryptophan hydroxylase 2 0.210589
IDO1 indoleamine 2,3-dioxygenase 1 0.209583
PNMA2 paraneoplastic Ma antigen 2 0.206913
CASP14 caspase 14, apoptosis-related cysteine peptidase 0.20658
NPTXR neuronal pentraxin receptor 0.205585
HMGA2 high mobility group AT-hook 2 0.205254
CTBP1 C-terminal binding protein 1 0.203275
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.199681
TSPO translocator protein (18kDa) 0.198709
TBP TATA box binding protein 0.196779
APOPT1 apoptogenic 1, mitochondrial 0.196139
TACSTD2 tumor-associated calcium signal transducer 2 0.195183
IL1B interleukin 1, beta 0.193915
CAMP cathelicidin antimicrobial peptide 0.192657
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.192031
IL18RAP interleukin 18 receptor accessory protein 0.191097
CDSN corneodesmosin 0.191097
PODXL podocalyxin-like 0.190786
LATS1 large tumor suppressor kinase 1 0.189551
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.189244
YY1 YY1 transcription factor 0.188938
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.188632
CD276 CD276 molecule 0.187719
ADA adenosine deaminase 0.187113
IL4 interleukin 4 0.185016
CRBN cereblon 0.183248
HAT1 histone acetyltransferase 1 0.182666
IRF9 interferon regulatory factor 9 0.180084
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 0.178682
EDA ectodysplasin A 0.177576
RBP2 retinol binding protein 2, cellular 0.177576
RPL5 ribosomal protein L5 0.176757
POU3F2 POU class 3 homeobox 2 0.176757
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 0.174881
GML glycosylphosphatidylinositol anchored molecule like 0.173571
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.173314
SPTA1 spectrin, alpha, erythrocytic 1 0.172291
PARG poly (ADP-ribose) glycohydrolase 0.172038
ADNP activity-dependent neuroprotector homeobox 0.171785
TG thyroglobulin 0.171286
THBS1 thrombospondin 1 0.170789
POMC proopiomelanocortin 0.170544
HBB hemoglobin, beta 0.167915
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.164149
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.163317
GTF2B general transcription factor IIB 0.162707
OXA1L oxidase (cytochrome c) assembly 1-like 0.161912
HLA-E major histocompatibility complex, class I, E 0.159658
GSTA3 glutathione S-transferase alpha 3 0.15948
GSTA2 glutathione S-transferase alpha 2 0.158778
DOCK8 dedicator of cytokinesis 8 0.158266
GSTA4 glutathione S-transferase alpha 4 0.158266
SP1 Sp1 transcription factor 0.144031
KLK5 kallikrein-related peptidase 5 0.143971
IFNL1 interferon, lambda 1 0.143942
KLK10 kallikrein-related peptidase 10 0.143937
CCL27 chemokine (C-C motif) ligand 27 0.143708
KLK8 kallikrein-related peptidase 8 0.143613
IL31 interleukin 31 0.143571
KLK6 kallikrein-related peptidase 6 0.142737
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.142573
ARG1 arginase 1 0.142366
IRF7 interferon regulatory factor 7 0.14215
DSG1 desmoglein 1 0.141915
KLK1 kallikrein 1 0.140649
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 0.140558
ADAM10 ADAM metallopeptidase domain 10 0.140538
SFTPA1 surfactant protein A1 0.139741
C4A complement component 4A (Rodgers blood group) 0.139284
HBD hemoglobin, delta 0.139037
KIF5B kinesin family member 5B 0.13852
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.138425
CCL17 chemokine (C-C motif) ligand 17 0.138386
DEFB4A defensin, beta 4A 0.136923
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.136803
FASN fatty acid synthase 0.136656
CNOT2 CCR4-NOT transcription complex, subunit 2 0.135778
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.135481
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.133242
HN1 hematological and neurological expressed 1 0.133223
RAG2 recombination activating gene 2 0.132747
APRT adenine phosphoribosyltransferase 0.132489
ICAM3 intercellular adhesion molecule 3 0.130882
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.130304
CFD complement factor D (adipsin) 0.12972
CXCL11 chemokine (C-X-C motif) ligand 11 0.128829
IDS iduronate 2-sulfatase 0.127592
GPANK1 G patch domain and ankyrin repeats 1 0.126564