heptaminol-7313 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the heptaminol-7313 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACRV1 acrosomal vesicle protein 1
ADCY6 adenylate cyclase 6
ALK anaplastic lymphoma receptor tyrosine kinase
ANTXR1 anthrax toxin receptor 1
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
C14ORF105 chromosome 14 open reading frame 105
C16ORF59 chromosome 16 open reading frame 59
CALD1 caldesmon 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CPEB1 cytoplasmic polyadenylation element binding protein 1
CREB5 cAMP responsive element binding protein 5
CTNND2 catenin (cadherin-associated protein), delta 2
DIO3 deiodinase, iodothyronine, type III
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
FAM63B family with sequence similarity 63, member B
FLJ11292
FMO5 flavin containing monooxygenase 5
FRMPD1 FERM and PDZ domain containing 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GALK2 galactokinase 2
GPR107 G protein-coupled receptor 107
GSK3A glycogen synthase kinase 3 alpha
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HDAC9 histone deacetylase 9
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HIST1H2BO histone cluster 1, H2bo
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HOMER3 homer scaffolding protein 3
HOXA4 homeobox A4
IFNA14 interferon, alpha 14
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
JAG1 jagged 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD17 potassium channel tetramerization domain containing 17
KLF13 Kruppel-like factor 13
LAMA2 laminin, alpha 2
LIMK2 LIM domain kinase 2
LOXL3 lysyl oxidase-like 3
LRRC61 leucine rich repeat containing 61
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LY86 lymphocyte antigen 86
MARS methionyl-tRNA synthetase
MBTD1 mbt domain containing 1
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MUC1 mucin 1, cell surface associated
MVK mevalonate kinase
NABP1 nucleic acid binding protein 1
NF1 neurofibromin 1
OSBP2 oxysterol binding protein 2
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PDE4D phosphodiesterase 4D, cAMP-specific
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDLIM7 PDZ and LIM domain 7 (enigma)
PHF20L1 PHD finger protein 20-like 1
PHLDA3 pleckstrin homology-like domain, family A, member 3
PILRA paired immunoglobin-like type 2 receptor alpha
PKP3 plakophilin 3
POM121L2 POM121 transmembrane nucleoporin-like 2
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PWAR5 Prader Willi/Angelman region RNA 5
RARA retinoic acid receptor, alpha
RBMS2 RNA binding motif, single stranded interacting protein 2
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RGS10 regulator of G-protein signaling 10
RGS12 regulator of G-protein signaling 12
RND2 Rho family GTPase 2
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RUNX1 runt-related transcription factor 1
SAYSD1 SAYSVFN motif domain containing 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMC1A structural maintenance of chromosomes 1A
SOGA1 suppressor of glucose, autophagy associated 1
SPTB spectrin, beta, erythrocytic
SREBF2 sterol regulatory element binding transcription factor 2
SRRT serrate, RNA effector molecule
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAOK2 TAO kinase 2
TBXA2R thromboxane A2 receptor
TEX261 testis expressed 261
THOC5 THO complex 5
TOB2 transducer of ERBB2, 2
TRIM14 tripartite motif containing 14
TUSC3 tumor suppressor candidate 3
UBOX5 U-box domain containing 5
UNC45A unc-45 homolog A (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZNF41 zinc finger protein 41

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACBD4 acyl-CoA binding domain containing 4
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANXA10 annexin A10
ASB13 ankyrin repeat and SOCS box containing 13
ASB8 ankyrin repeat and SOCS box containing 8
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BCORL1 BCL6 corepressor-like 1
C6ORF47 chromosome 6 open reading frame 47
CA5BP1 carbonic anhydrase VB pseudogene 1
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBR4 carbonyl reductase 4
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC68 coiled-coil domain containing 68
CCDC85C coiled-coil domain containing 85C
CCNJL cyclin J-like
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDADC1 cytidine and dCMP deaminase domain containing 1
CDON cell adhesion associated, oncogene regulated
CENPO centromere protein O
CFAP69 cilia and flagella associated protein 69
CLDN15 claudin 15
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CORO1A coronin, actin binding protein, 1A
CTSF cathepsin F
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DLK1 delta-like 1 homolog (Drosophila)
DNAL4 dynein, axonemal, light chain 4
DTWD1 DTW domain containing 1
EPN2 epsin 2
EPN3 epsin 3
F3 coagulation factor III (thromboplastin, tissue factor)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FUZ fuzzy planar cell polarity protein
HHLA3 HERV-H LTR-associating 3
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
KIAA0319L KIAA0319-like
KPTN kaptin (actin binding protein)
L2HGDH L-2-hydroxyglutarate dehydrogenase
LMCD1 LIM and cysteine-rich domains 1
MANBA mannosidase, beta A, lysosomal
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK12 mitogen-activated protein kinase 12
METTL16 methyltransferase like 16
MFGE8 milk fat globule-EGF factor 8 protein
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MN1 meningioma (disrupted in balanced translocation) 1
MON1B MON1 secretory trafficking family member B
MPP1 membrane protein, palmitoylated 1, 55kDa
MX1 MX dynamin-like GTPase 1
NME5 NME/NM23 family member 5
NXPH4 neurexophilin 4
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSMR oncostatin M receptor
P3H2 prolyl 3-hydroxylase 2
PACS1 phosphofurin acidic cluster sorting protein 1
PARD6A par-6 family cell polarity regulator alpha
PAX9 paired box 9
PEX13 peroxisomal biogenesis factor 13
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRICKLE3 prickle homolog 3 (Drosophila)
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RPP25 ribonuclease P/MRP 25kDa subunit
RPS21 ribosomal protein S21
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUNDC3B RUN domain containing 3B
S100A3 S100 calcium binding protein A3
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC25A40 solute carrier family 25, member 40
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SOX12 SRY (sex determining region Y)-box 12
SPEG SPEG complex locus
STAR steroidogenic acute regulatory protein
SUGCT succinyl-CoA:glutarate-CoA transferase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEAD3 TEA domain family member 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM183A transmembrane protein 183A
TMEM242 transmembrane protein 242
TRAIP TRAF interacting protein
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UBQLN4 ubiquilin 4
USP27X ubiquitin specific peptidase 27, X-linked
ZNF180 zinc finger protein 180
ZNF254 zinc finger protein 254
ZNF34 zinc finger protein 34
ZNF415 zinc finger protein 415
ZNF552 zinc finger protein 552
ZXDC ZXD family zinc finger C