hepatopulmonary syndrome; liver cirrhosis Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group unknown (Genetic Association Database)
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Genes

94 genes associated with the disease hepatopulmonary syndrome; liver cirrhosis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACVRL1 activin A receptor type II-like 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPT1 angiopoietin 1
APOE apolipoprotein E
BAX BCL2-associated X protein
BHMT betaine--homocysteine S-methyltransferase
BMPR1A bone morphogenetic protein receptor, type IA
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
C4A complement component 4A (Rodgers blood group)
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CAV3 caveolin 3
CBS cystathionine-beta-synthase
CD14 CD14 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CELA1 chymotrypsin-like elastase family, member 1
COL18A1 collagen, type XVIII, alpha 1
CRP C-reactive protein, pentraxin-related
CYBB cytochrome b-245, beta polypeptide
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
ELANE elastase, neutrophil expressed
ELN elastin
ENG endoglin
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F9 coagulation factor IX
GDF2 growth differentiation factor 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
LBP lipopolysaccharide binding protein
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX1 NADPH oxidase 1
NOX4 NADPH oxidase 4
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
PDE5A phosphodiesterase 5A, cGMP-specific
PI3 peptidase inhibitor 3, skin-derived
PLG plasminogen
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCG protein kinase C, gamma
PTGIS prostaglandin I2 (prostacyclin) synthase
RARA retinoic acid receptor, alpha
RARB retinoic acid receptor, beta
RARG retinoic acid receptor, gamma
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RUNX1 runt-related transcription factor 1
S100A4 S100 calcium binding protein A4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHBG sex hormone-binding globulin
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
THBS1 thrombospondin 1
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TNC tenascin C
TNF tumor necrosis factor
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
TRPC6 transient receptor potential cation channel, subfamily C, member 6
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor
XDH xanthine dehydrogenase