hepatitis c Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis C virus, which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice. (Human Disease Ontology, DOID_1883)
Similar Terms
Downloads & Tools

Genes

359 genes co-occuring with the disease hepatitis c in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
IFNL3 interferon, lambda 3 3.00561
IFNA1 interferon, alpha 1 2.95262
IFNA2 interferon, alpha 2 2.76962
GOT1 glutamic-oxaloacetic transaminase 1, soluble 2.02929
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.99872
KRAS Kirsten rat sarcoma viral oncogene homolog 1.96942
SOS1 son of sevenless homolog 1 (Drosophila) 1.92998
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.88113
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 1.83636
CD4 CD4 molecule 1.75641
GGT1 gamma-glutamyltransferase 1 1.66285
CD81 CD81 molecule 1.56978
BOC BOC cell adhesion associated, oncogene regulated 1.54539
IFNA17 interferon, alpha 17 1.53568
FBL fibrillarin 1.53392
IFNA21 interferon, alpha 21 1.52556
FTH1 ferritin, heavy polypeptide 1 1.52468
FTL ferritin, light polypeptide 1.52468
FBLL1 fibrillarin-like 1 1.48165
HFE hemochromatosis 1.44079
GGT2 gamma-glutamyltransferase 2 1.41271
AFP alpha-fetoprotein 1.39389
IFNB1 interferon, beta 1, fibroblast 1.37338
ALB albumin 1.35943
CLTC clathrin, heavy chain (Hc) 1.35681
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene 1.33632
CXCL10 chemokine (C-X-C motif) ligand 10 1.32236
MX1 MX dynamin-like GTPase 1 1.26647
HAMP hepcidin antimicrobial peptide 1.25558
ISG20 interferon stimulated exonuclease gene 20kDa 1.22779
F2 coagulation factor II (thrombin) 1.22779
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 1.22518
ISG15 ISG15 ubiquitin-like modifier 1.22302
PNPLA3 patatin-like phospholipase domain containing 3 1.21912
STAT1 signal transducer and activator of transcription 1, 91kDa 1.21868
IFNL2 interferon, lambda 2 1.18798
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta 1.18109
IL10 interleukin 10 1.15666
TNF tumor necrosis factor 1.14942
TF transferrin 1.13755
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.11603
HLA-C major histocompatibility complex, class I, C 1.11099
IFI27 interferon, alpha-inducible protein 27 1.1072
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.09839
MUT methylmalonyl CoA mutase 1.08957
IFNAR2 interferon (alpha, beta and omega) receptor 2 1.0816
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 1.05093
ALPPL2 alkaline phosphatase, placental-like 2 1.04083
ALPP alkaline phosphatase, placental 1.04041
ALPL alkaline phosphatase, liver/bone/kidney 1.03956
IFNL1 interferon, lambda 1 1.0362
SOCS3 suppressor of cytokine signaling 3 1.02735
USP18 ubiquitin specific peptidase 18 1.01301
IFI44 interferon-induced protein 44 0.986849
TGFB1 transforming growth factor, beta 1 0.985164
TIMP1 TIMP metallopeptidase inhibitor 1 0.9839
TLR3 toll-like receptor 3 0.97086
ENAM enamelin 0.949102
NCAM1 neural cell adhesion molecule 1 0.938704
CXCR3 chemokine (C-X-C motif) receptor 3 0.935799
KRT18 keratin 18, type I 0.930414
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 0.920498
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.919673
HLA-A major histocompatibility complex, class I, A 0.908142
INS insulin 0.904032
LEP leptin 0.893359
TLR7 toll-like receptor 7 0.887618
STAT2 signal transducer and activator of transcription 2, 113kDa 0.867549
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.861409
HBE1 hemoglobin, epsilon 1 0.840115
MTTP microsomal triglyceride transfer protein 0.835198
THPO thrombopoietin 0.834378
CXCL9 chemokine (C-X-C motif) ligand 9 0.820026
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 0.801564
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 0.795002
IRF7 interferon regulatory factor 7 0.794181
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.793771
HSF4 heat shock transcription factor 4 0.790081
IL1B interleukin 1, beta 0.789262
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 0.786394
CD86 CD86 molecule 0.781479
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.781069
CUTA cutA divalent cation tolerance homolog (E. coli) 0.77575
TLR2 toll-like receptor 2 0.77207
IL6 interleukin 6 0.755749
CD19 CD19 molecule 0.733001
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 0.72612
PRF1 perforin 1 (pore forming protein) 0.715215
DEPDC5 DEP domain containing 5 0.714408
CARTPT CART prepropeptide 0.712796
CXCL11 chemokine (C-X-C motif) ligand 11 0.697109
IL4 interleukin 4 0.691094
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.682693
EPO erythropoietin 0.679499
IRF1 interferon regulatory factor 1 0.678701
F8 coagulation factor VIII, procoagulant component 0.663975
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 0.661594
HP haptoglobin 0.656837
DDRGK1 DDRGK domain containing 1 0.656441
TMEM50A transmembrane protein 50A 0.656441
SIKE1 suppressor of IKBKE 1 0.656046
HPR haptoglobin-related protein 0.650508
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.650508
OASL 2'-5'-oligoadenylate synthetase-like 0.649718
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.647743
CD27 CD27 molecule 0.645375
ERVW-1 endogenous retrovirus group W, member 1 0.643797
TLR4 toll-like receptor 4 0.642615
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.641433
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.637102
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.630813
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.625711
ICAM1 intercellular adhesion molecule 1 0.6214
CD83 CD83 molecule 0.61866
FOXP3 forkhead box P3 0.616312
MIA2 melanoma inhibitory activity 2 0.616312
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.606543
CD80 CD80 molecule 0.60303
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.59952
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 0.592895
MMP2 matrix metallopeptidase 2 0.592116
FASLG Fas ligand (TNF superfamily, member 6) 0.591337
CD82 CD82 molecule 0.586276
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.585887
TPO thyroid peroxidase 0.581217
IL2RA interleukin 2 receptor, alpha 0.580439
PIAS1 protein inhibitor of activated STAT, 1 0.578494
NELFCD negative elongation factor complex member C/D 0.571107
IL7R interleukin 7 receptor 0.571107
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 0.570329
CREM cAMP responsive element modulator 0.567997
MMP1 matrix metallopeptidase 1 0.565666
LTF lactotransferrin 0.565277
IDO1 indoleamine 2,3-dioxygenase 1 0.560227
CD69 CD69 molecule 0.558285
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.55712
MBL2 mannose-binding lectin (protein C) 2, soluble 0.551298
LSM12 LSM12 homolog (S. cerevisiae) 0.541605
CPT1A carnitine palmitoyltransferase 1A (liver) 0.538118
ASGR2 asialoglycoprotein receptor 2 0.536957
MPL MPL proto-oncogene, thrombopoietin receptor 0.535409
HAVCR2 hepatitis A virus cellular receptor 2 0.533475
IL2 interleukin 2 0.533088
LAMP1 lysosomal-associated membrane protein 1 0.531541
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.530381
HLA-E major histocompatibility complex, class I, E 0.52729
IRF3 interferon regulatory factor 3 0.525746
CNR1 cannabinoid receptor 1 (brain) 0.52343
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 0.521888
B3GAT1 beta-1,3-glucuronyltransferase 1 0.521888
TFR2 transferrin receptor 2 0.521888
ASGR1 asialoglycoprotein receptor 1 0.520346
RSAD2 radical S-adenosyl methionine domain containing 2 0.51919
LSM10 LSM10, U7 small nuclear RNA associated 0.518034
SREBF1 sterol regulatory element binding transcription factor 1 0.514186
IL18 interleukin 18 0.509192
CD79A CD79a molecule, immunoglobulin-associated alpha 0.506123
IFI6 interferon, alpha-inducible protein 6 0.505739
MED9 mediator complex subunit 9 0.503441
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.499614
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.497321
SOCS1 suppressor of cytokine signaling 1 0.496939
GSTA3 glutathione S-transferase alpha 3 0.493885
GSTA2 glutathione S-transferase alpha 2 0.49274
GSTA4 glutathione S-transferase alpha 4 0.491597
APOB apolipoprotein B 0.486266
GSTA1 glutathione S-transferase alpha 1 0.485505
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.479047
CCL3 chemokine (C-C motif) ligand 3 0.477151
CCR2 chemokine (C-C motif) receptor 2 0.470711
APOA1 apolipoprotein A-I 0.46655
TRIM22 tripartite motif containing 22 0.465038
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 0.463905
IRF9 interferon regulatory factor 9 0.463905
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.462394
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8 0.458619
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.456732
CD68 CD68 molecule 0.447687
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.446558
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.443171
MAVS mitochondrial antiviral signaling protein 0.43753
CCL2 chemokine (C-C motif) ligand 2 0.431144
FTCD formimidoyltransferase cyclodeaminase 0.429642
TLR9 toll-like receptor 9 0.428516
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.42814
DBR1 debranching RNA lariats 1 0.424389
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.421765
IFNE interferon, epsilon 0.421016
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.416521
RETN resistin 0.416147
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 0.415398
LDLR low density lipoprotein receptor 0.413901
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 0.413527
KLRC2 killer cell lectin-like receptor subfamily C, member 2 0.410535
OCLN occludin 0.409414
KRT8 keratin 8, type II 0.408292
TYK2 tyrosine kinase 2 0.407919
CASP5 caspase 5, apoptosis-related cysteine peptidase 0.407172
GC group-specific component (vitamin D binding protein) 0.407172
HLA-B major histocompatibility complex, class I, B 0.400826
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.399707
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.398962
RPS27L ribosomal protein S27-like 0.397098
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 0.394863
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.393374
STXBP5L syntaxin binding protein 5-like 0.389281
CD38 CD38 molecule 0.384822
FCRL4 Fc receptor-like 4 0.382223
B2M beta-2-microglobulin 0.379997
KRT7 keratin 7, type II 0.379256
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.373698
IRF2 interferon regulatory factor 2 0.372587
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.372587
IFNLR1 interferon, lambda receptor 1 0.371847
TFRC transferrin receptor 0.370368
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.369628
NAMPT nicotinamide phosphoribosyltransferase 0.365932
NCR1 natural cytotoxicity triggering receptor 1 0.365932
CD5 CD5 molecule 0.354131
UROD uroporphyrinogen decarboxylase 0.353763
IL10RA interleukin 10 receptor, alpha 0.352659
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.352291
IFI44L interferon-induced protein 44-like 0.350084
CABP1 calcium binding protein 1 0.348614
CRP C-reactive protein, pentraxin-related 0.346042
JAK1 Janus kinase 1 0.345308
IFITM1 interferon induced transmembrane protein 1 0.342372
LSM1 LSM1, U6 small nuclear RNA associated 0.340906
STMN2 stathmin 2 0.339806
PCBP2 poly(rC) binding protein 2 0.33944
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.338707
GPX5 glutathione peroxidase 5 0.337975
IRF8 interferon regulatory factor 8 0.337608
SMAD3 SMAD family member 3 0.33651
GPX4 glutathione peroxidase 4 0.335046
ICOS inducible T-cell co-stimulator 0.334681
TG thyroglobulin 0.3292
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.326646
ACTG1 actin gamma 1 0.325552
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 0.321181
GPX1 glutathione peroxidase 1 0.32009
CXCL8 chemokine (C-X-C motif) ligand 8 0.32009
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.317545
PRMT1 protein arginine methyltransferase 1 0.316092
VCAM1 vascular cell adhesion molecule 1 0.315366
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.31029
OTOR otoraplin 0.308842
MICA MHC class I polypeptide-related sequence A 0.30848
CLDN1 claudin 1 0.306672
CABIN1 calcineurin binding protein 1 0.304503
CCL4 chemokine (C-C motif) ligand 4 0.30342
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 0.302698
COPG1 coatomer protein complex, subunit gamma 1 0.301615
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.300533
KRT19 keratin 19, type I 0.298371
IFNA4 interferon, alpha 4 0.298371
ADAR adenosine deaminase, RNA-specific 0.295132
RBP4 retinol binding protein 4, plasma 0.294053
CLDN7 claudin 7 0.293694
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 0.290462
NCAPG non-SMC condensin I complex, subunit G 0.290462
MMP9 matrix metallopeptidase 9 0.287952
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 0.287593
SPP1 secreted phosphoprotein 1 0.280439
TP53 tumor protein p53 0.280439
FAS Fas cell surface death receptor 0.280439
CD40LG CD40 ligand 0.277584
CD1C CD1c molecule 0.277584
MYD88 myeloid differentiation primary response 88 0.277584
PPA2 pyrophosphatase (inorganic) 2 0.268332
SOD2 superoxide dismutase 2, mitochondrial 0.268332
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.267622
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 0.267267
OR2B2 olfactory receptor, family 2, subfamily B, member 2 0.267267
CCL5 chemokine (C-C motif) ligand 5 0.266203
CEP164 centrosomal protein 164kDa 0.263368
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.261952
PTBP1 polypyrimidine tract binding protein 1 0.261245
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.258417
LTA lymphotoxin alpha 0.250663
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.249257
IFNG interferon, gamma 0.243995
IRS1 insulin receptor substrate 1 0.243995
ARG1 arginase 1 0.241895
NKRF NFKB repressing factor 0.238752
UBP1 upstream binding protein 1 (LBP-1a) 0.237009
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 0.235964
SCARA5 scavenger receptor class A, member 5 0.232489
PCNA proliferating cell nuclear antigen 0.230755
C4A complement component 4A (Rodgers blood group) 0.230063
B3GAT2 beta-1,3-glucuronyltransferase 2 0.227297
FGD1 FYVE, RhoGEF and PH domain containing 1 0.226952
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.22454
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 0.223165
CCL8 chemokine (C-C motif) ligand 8 0.220766
F9 coagulation factor IX 0.220081
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.218374
FPR1 formyl peptide receptor 1 0.214975
LCK LCK proto-oncogene, Src family tyrosine kinase 0.213959
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 0.213621
JUN jun proto-oncogene 0.212271
ZNF675 zinc finger protein 675 0.212271
CD40 CD40 molecule, TNF receptor superfamily member 5 0.211934
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.210589
CCR7 chemokine (C-C motif) receptor 7 0.207912
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.205585
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.203604
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.203604
NXT1 nuclear transport factor 2-like export factor 1 0.202618
FGL2 fibrinogen-like 2 0.199033
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.198064
CYGB cytoglobin 0.198064
RCC1 regulator of chromosome condensation 1 0.197099
TRIM37 tripartite motif containing 37 0.196779
ATAD5 ATPase family, AAA domain containing 5 0.19582
JAK2 Janus kinase 2 0.194865
PMM1 phosphomannomutase 1 0.191408
RPS3A ribosomal protein S3A 0.191408
SPAG1 sperm associated antigen 1 0.191408
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.191097
C3ORF18 chromosome 3 open reading frame 18 0.189244
FBXL20 F-box and leucine-rich repeat protein 20 0.186811
FCAR Fc fragment of IgA receptor 0.185313
ALLC allantoicase 0.185016
PRKCDBP protein kinase C, delta binding protein 0.184424
MED23 mediator complex subunit 23 0.183248
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.181222
CLEC3A C-type lectin domain family 3, member A 0.180652
RPS27 ribosomal protein S27 0.178682
PPARG peroxisome proliferator-activated receptor gamma 0.178403
CNR2 cannabinoid receptor 2 (macrophage) 0.177851
CLEC2B C-type lectin domain family 2, member B 0.177029
IFNA5 interferon, alpha 5 0.175947
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.175679
IGF1 insulin-like growth factor 1 (somatomedin C) 0.174881
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.174093
DGAT1 diacylglycerol O-acyltransferase 1 0.171036
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 0.170299
FGF21 fibroblast growth factor 21 0.167682
HMOX1 heme oxygenase 1 0.166995
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.166095
MKI67 marker of proliferation Ki-67 0.165655
TXN thioredoxin 0.165435
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.162908
THEM5 thioesterase superfamily member 5 0.162908
CST3 cystatin C 0.162505
CLEC10A C-type lectin domain family 10, member A 0.162306
PDCD1 programmed cell death 1 0.162109
PRTN3 proteinase 3 0.161523
MFAP4 microfibrillar-associated protein 4 0.161331
NPC1L1 NPC1-like 1 0.161139
DPP4 dipeptidyl-peptidase 4 0.160021
CCL13 chemokine (C-C motif) ligand 13 0.160021
MAPK8 mitogen-activated protein kinase 8 0.15948
NOXA1 NADPH oxidase activator 1 0.159302
FOXO1 forkhead box O1 0.159124
IFNGR1 interferon gamma receptor 1 0.158434
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.157929
TIMP2 TIMP metallopeptidase inhibitor 2 0.157602