hepatitis c, chronic; liver cirrhosis Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group infection (Genetic Association Database)
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Genes

66 genes associated with the disease hepatitis c, chronic; liver cirrhosis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ADAR adenosine deaminase, RNA-specific
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
APOE apolipoprotein E
C5 complement component 5
CD14 CD14 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
HFE hemochromatosis
IFNA1 interferon, alpha 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL4 interleukin 4
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
JAK1 Janus kinase 1
KRT8 keratin 8, type II
LTBP1 latent transforming growth factor beta binding protein 1
LTBP2 latent transforming growth factor beta binding protein 2
LTBP3 latent transforming growth factor beta binding protein 3
LTBP4 latent transforming growth factor beta binding protein 4
MBL2 mannose-binding lectin (protein C) 2, soluble
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
MMP11 matrix metallopeptidase 11
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MMP25 matrix metallopeptidase 25
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MX1 MX dynamin-like GTPase 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STXBP5L syntaxin binding protein 5-like
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TYK2 tyrosine kinase 2