hepatic vascular disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A vascular disease that is located_in the liver. (Human Disease Ontology, DOID_272)
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Genes

273 genes co-occuring with the disease hepatic vascular disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
F2 coagulation factor II (thrombin) 1.98482
ALB albumin 1.9652
F5 coagulation factor V (proaccelerin, labile factor) 1.82368
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.67096
EVL Enah/Vasp-like 1.63769
SST somatostatin 1.61262
NOS3 nitric oxide synthase 3 (endothelial cell) 1.58448
AFP alpha-fetoprotein 1.58359
PROS1 protein S (alpha) 1.49482
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.45133
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.43157
ALPPL2 alkaline phosphatase, placental-like 2 1.42718
ALPP alkaline phosphatase, placental 1.42674
ALPL alkaline phosphatase, liver/bone/kidney 1.4263
EDN1 endothelin 1 1.40658
JAK2 Janus kinase 2 1.39346
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.37294
GCG glucagon 1.21478
UTS2 urotensin 2 1.17421
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 1.16435
REN renin 1.1588
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.998236
GGT1 gamma-glutamyltransferase 1 0.978426
F3 coagulation factor III (thromboplastin, tissue factor) 0.964148
F8 coagulation factor VIII, procoagulant component 0.937044
THPO thrombopoietin 0.896641
EDNRA endothelin receptor type A 0.888848
AVP arginine vasopressin 0.883521
HMOX1 heme oxygenase 1 0.883111
PLAT plasminogen activator, tissue 0.844211
MSN moesin 0.801154
UTS2R urotensin 2 receptor 0.760231
RAB3D RAB3D, member RAS oncogene family 0.759416
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) 0.74761
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.74436
INS insulin 0.739894
NOSIP nitric oxide synthase interacting protein 0.734622
VWF von Willebrand factor 0.714005
EDNRB endothelin receptor type B 0.709169
TGFB1 transforming growth factor, beta 1 0.694301
GGT2 gamma-glutamyltransferase 2 0.678302
PGF placental growth factor 0.671527
MLX MLX, MAX dimerization protein 0.668345
SLC22A20 solute carrier family 22, member 20 0.648138
NPR1 natriuretic peptide receptor 1 0.646559
GUCY2C guanylate cyclase 2C 0.64577
TNF tumor necrosis factor 0.644981
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.644981
LBP lipopolysaccharide binding protein 0.63907
FN1 fibronectin 1 0.617486
TIMP1 TIMP metallopeptidase inhibitor 1 0.614747
FBL fibrillarin 0.614747
CNR1 cannabinoid receptor 1 (brain) 0.612792
PLG plasminogen 0.597961
CD79A CD79a molecule, immunoglobulin-associated alpha 0.596012
NOS1 nitric oxide synthase 1 (neuronal) 0.590169
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.577716
RPL36 ribosomal protein L36 0.562558
VEGFA vascular endothelial growth factor A 0.557509
FBLL1 fibrillarin-like 1 0.557509
MUCL1 mucin-like 1 0.553627
HBA2 hemoglobin, alpha 2 0.551686
CTGF connective tissue growth factor 0.541217
BCHE butyrylcholinesterase 0.53928
PCDHA10 protocadherin alpha 10 0.532701
SAA1 serum amyloid A1 0.521888
PRKCSH protein kinase C substrate 80K-H 0.521117
RELT RELT tumor necrosis factor receptor 0.519575
HBA1 hemoglobin, alpha 1 0.509959
PCNA proliferating cell nuclear antigen 0.499614
APEH acylaminoacyl-peptide hydrolase 0.488169
APLNR apelin receptor 0.483224
NOSTRIN nitric oxide synthase trafficking 0.481325
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.477909
PTPRE protein tyrosine phosphatase, receptor type, E 0.47753
KLF2 Kruppel-like factor 2 0.474119
GAST gastrin 0.463905
CD59 CD59 molecule, complement regulatory protein 0.462016
ACE angiotensin I converting enzyme 0.461639
MARS methionyl-tRNA synthetase 0.460506
IFNA1 interferon, alpha 1 0.458996
IL6 interleukin 6 0.457109
LIN9 lin-9 DREAM MuvB core complex component 0.456355
ERAS ES cell expressed Ras 0.452208
ACER3 alkaline ceramidase 3 0.442418
IL31RA interleukin 31 receptor A 0.438282
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.437906
F12 coagulation factor XII (Hageman factor) 0.429266
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.420641
COL14A1 collagen, type XIV, alpha 1 0.400826
CAV1 caveolin 1, caveolae protein, 22kDa 0.397843
IGLV1-36 immunoglobulin lambda variable 1-36 0.393374
CD4 CD4 molecule 0.391885
ARRB2 arrestin, beta 2 0.390769
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.389653
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 0.381481
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.379626
THBD thrombomodulin 0.374438
CRP C-reactive protein, pentraxin-related 0.372958
C8B complement component 8, beta polypeptide 0.371847
CD34 CD34 molecule 0.368518
NOS2 nitric oxide synthase 2, inducible 0.36741
APOH apolipoprotein H (beta-2-glycoprotein I) 0.365193
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.364824
ANGPT1 angiopoietin 1 0.351187
HAVCR2 hepatitis A virus cellular receptor 2 0.347144
KNG1 kininogen 1 0.346777
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.344941
SOD2 superoxide dismutase 2, mitochondrial 0.343473
LCOR ligand dependent nuclear receptor corepressor 0.342006
HINT1 histidine triad nucleotide binding protein 1 0.33944
CAT catalase 0.339073
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.338707
POLL polymerase (DNA directed), lambda 0.337608
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.333949
TPMT thiopurine S-methyltransferase 0.330295
TIMP2 TIMP metallopeptidase inhibitor 2 0.330295
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.328469
NPPA natriuretic peptide A 0.326281
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.325187
MPL MPL proto-oncogene, thrombopoietin receptor 0.321545
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.311377
JMJD6 jumonji domain containing 6 0.304864
CLEC3A C-type lectin domain family 3, member A 0.304503
CALCA calcitonin-related polypeptide alpha 0.303059
TBXAS1 thromboxane A synthase 1 (platelet) 0.299812
CLEC2B C-type lectin domain family 2, member B 0.299812
RPAP3 RNA polymerase II associated protein 3 0.296571
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y 0.289027
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 0.287235
MMP9 matrix metallopeptidase 9 0.28616
PRMT1 protein arginine methyltransferase 1 0.28616
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.284371
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.281153
PDE5A phosphodiesterase 5A, cGMP-specific 0.281153
CLEC10A C-type lectin domain family 10, member A 0.277584
CPB2 carboxypeptidase B2 (plasma) 0.277227
ACVRL1 activin A receptor type II-like 1 0.269398
APLN apelin 0.268332
AQP1 aquaporin 1 (Colton blood group) 0.26266
TRA2B transformer 2 beta homolog (Drosophila) 0.256299
TYK2 tyrosine kinase 2 0.255241
NLRP6 NLR family, pyrin domain containing 6 0.252774
ASGR2 asialoglycoprotein receptor 2 0.252422
PRB3 proline-rich protein BstNI subfamily 3 0.24996
CD163 CD163 molecule 0.245747
AASS aminoadipate-semialdehyde synthase 0.244696
MAOA monoamine oxidase A 0.243995
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.243995
ASGR1 asialoglycoprotein receptor 1 0.237706
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.237706
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.237706
IL1B interleukin 1, beta 0.235964
FTL ferritin, light polypeptide 0.233183
FTH1 ferritin, heavy polypeptide 1 0.232836
PGA3 pepsinogen 3, group I (pepsinogen A) 0.232489
PGA4 pepsinogen 4, group I (pepsinogen A) 0.232489
GPANK1 G patch domain and ankyrin repeats 1 0.231448
IGF1 insulin-like growth factor 1 (somatomedin C) 0.228679
CTH cystathionine gamma-lyase 0.225573
GJA4 gap junction protein, alpha 4, 37kDa 0.222822
SETD2 SET domain containing 2 0.220424
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.215653
LECT2 leukocyte cell-derived chemotaxin 2 0.214636
CD1C CD1c molecule 0.212608
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 0.212608
HFE hemochromatosis 0.212608
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.211261
MMP2 matrix metallopeptidase 2 0.210253
CP ceruloplasmin (ferroxidase) 0.198064
SEPT7 septin 7 0.194232
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.192657
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.191097
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.189859
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.189551
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.189551
GPX5 glutathione peroxidase 5 0.185313
EPHB4 EPH receptor B4 0.185313
NT5E 5'-nucleotidase, ecto (CD73) 0.184424
FAM132A family with sequence similarity 132, member A 0.184424
GPX4 glutathione peroxidase 4 0.182957
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 0.177576
TBX22 T-box 22 0.176757
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.175947
LARS leucyl-tRNA synthetase 0.174881
RXFP1 relaxin/insulin-like family peptide receptor 1 0.174881
NPY neuropeptide Y 0.174354
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.174093
STPG1 sperm-tail PG-rich repeat containing 1 0.172544
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 0.172544
EFNB2 ephrin-B2 0.172038
GPX1 glutathione peroxidase 1 0.171785
MYLK3 myosin light chain kinase 3 0.171535
HRH2 histamine receptor H2 0.171535
ADM adrenomedullin 0.171036
PDE9A phosphodiesterase 9A 0.170054
F13A1 coagulation factor XIII, A1 polypeptide 0.166544
IFT122 intraflagellar transport 122 0.164359
FBXO2 F-box protein 2 0.160574
CNR2 cannabinoid receptor 2 (macrophage) 0.160387
WT1 Wilms tumor 1 0.159302
WRAP73 WD repeat containing, antisense to TP73 0.141089
KRT3 keratin 3, type II 0.140324
GRHL1 grainyhead-like 1 (Drosophila) 0.138403
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.138297
SORD sorbitol dehydrogenase 0.135285
HP haptoglobin 0.134675
HPR haptoglobin-related protein 0.134529
PNMA2 paraneoplastic Ma antigen 2 0.13388
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.13254
FGD1 FYVE, RhoGEF and PH domain containing 1 0.132425
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.131989
STMN2 stathmin 2 0.131251
BCL2L1 BCL2-like 1 0.131159
HCCS holocytochrome c synthase 0.129315
FIP1L1 factor interacting with PAPOLA and CPSF1 0.128764
VIM vimentin 0.128666
PHF12 PHD finger protein 12 0.127333
RERE arginine-glutamic acid dipeptide (RE) repeats 0.124073
SELL selectin L 0.123642
BLVRB biliverdin reductase B 0.123549
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.12334
BAX BCL2-associated X protein 0.122937
MIRLET7C microRNA let-7c 0.122352
MON1A MON1 secretory trafficking family member A 0.121646
C5 complement component 5 0.121311
ZNF77 zinc finger protein 77 0.121071
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.11901
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 0.118296
PRDM2 PR domain containing 2, with ZNF domain 0.118084
CYS1 cystin 1 0.117841
SETD1A SET domain containing 1A 0.116768
IL7R interleukin 7 receptor 0.116703
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.116381
WIPF2 WAS/WASL interacting protein family, member 2 0.115983
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.115517
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.115414
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.113914
CLCN5 chloride channel, voltage-sensitive 5 0.11326
MTA1 metastasis associated 1 0.111603
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.110742
LEP leptin 0.108868
S1PR2 sphingosine-1-phosphate receptor 2 0.108868
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.108066
GPR135 G protein-coupled receptor 135 0.108023
ABHD5 abhydrolase domain containing 5 0.107719
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.107589
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.107503
A1BG alpha-1-B glycoprotein 0.107459
XDH xanthine dehydrogenase 0.107416
VASH1 vasohibin 1 0.107242
ARRB1 arrestin, beta 1 0.106893
SRCIN1 SRC kinase signaling inhibitor 1 0.106759
WRNIP1 Werner helicase interacting protein 1 0.106269
IFNGR1 interferon gamma receptor 1 0.105685
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.105593
NPPC natriuretic peptide C 0.105136
XPR1 xenotropic and polytropic retrovirus receptor 1 0.104723
FDPS farnesyl diphosphate synthase 0.104536
TUBGCP4 tubulin, gamma complex associated protein 4 0.104348
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.104301
IL2RA interleukin 2 receptor, alpha 0.104254
GSTA3 glutathione S-transferase alpha 3 0.103879
ARG1 arginase 1 0.103832
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.103786
GSTA2 glutathione S-transferase alpha 2 0.103739
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.103692
GSTA4 glutathione S-transferase alpha 4 0.103597
MEOX2 mesenchyme homeobox 2 0.103597
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 0.103212
GSTA1 glutathione S-transferase alpha 1 0.102828
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.102393
KRT18 keratin 18, type I 0.102245