hematological neoplasm Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0004377
Similar Terms
Downloads & Tools

Genes

176 genes associated with the hematological neoplasm phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADA adenosine deaminase
ARHGAP26 Rho GTPase activating protein 26
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ASXL1 additional sex combs like transcriptional regulator 1
ATM ATM serine/threonine kinase
ATRX alpha thalassemia/mental retardation syndrome X-linked
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
BIRC3 baculoviral IAP repeat containing 3
BLM Bloom syndrome, RecQ helicase-like
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CALR calreticulin
CASP10 caspase 10, apoptosis-related cysteine peptidase
CBFB core-binding factor, beta subunit
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCND1 cyclin D1
CD19 CD19 molecule
CD27 CD27 molecule
CD81 CD81 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP57 centrosomal protein 57kDa
CES1 carboxylesterase 1
CHD7 chromodomain helicase DNA binding protein 7
CHEK2 checkpoint kinase 2
COL14A1 collagen, type XIV, alpha 1
CR2 complement component (3d/Epstein Barr virus) receptor 2
CSF3R colony stimulating factor 3 receptor (granulocyte)
CTC1 CTS telomere maintenance complex component 1
DCLRE1C DNA cross-link repair 1C
DKC1 dyskeratosis congenita 1, dyskerin
DNASE1L3 deoxyribonuclease I-like 3
ELANE elastase, neutrophil expressed
ERCC4 excision repair cross-complementation group 4
ETV6 ets variant 6
EVC Ellis van Creveld protein
EVC2 Ellis van Creveld syndrome 2
FANCA Fanconi anemia, complementation group A
FANCB Fanconi anemia, complementation group B
FANCC Fanconi anemia, complementation group C
FANCD2 Fanconi anemia, complementation group D2
FANCE Fanconi anemia, complementation group E
FANCF Fanconi anemia, complementation group F
FANCG Fanconi anemia, complementation group G
FANCI Fanconi anemia, complementation group I
FANCL Fanconi anemia, complementation group L
FANCM Fanconi anemia, complementation group M
FLT3 fms-related tyrosine kinase 3
FOXP1 forkhead box P1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GBA glucosidase, beta, acid
GFI1 growth factor independent 1 transcription repressor
GFI1B growth factor independent 1B transcription repressor
GMPS guanine monphosphate synthase
HAX1 HCLS1 associated protein X-1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
ICOS inducible T-cell co-stimulator
IGHV4-34 immunoglobulin heavy variable 4-34
IL2RG interleukin 2 receptor, gamma
IL7R interleukin 7 receptor
IRF4 interferon regulatory factor 4
ITK IL2-inducible T-cell kinase
JAK2 Janus kinase 2
KIF11 kinesin family member 11
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHDC8B kelch domain containing 8B
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LIG4 ligase IV, DNA, ATP-dependent
LPP LIM domain containing preferred translocation partner in lipoma
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAGT1 magnesium transporter 1
MALT1 MALT1 paracaspase
MCM4 minichromosome maintenance complex component 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLF1 myeloid leukemia factor 1
MLH1 mutL homolog 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MPL MPL proto-oncogene, thrombopoietin receptor
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NBEAL2 neurobeachin-like 2
NBN nibrin
NF1 neurofibromin 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NHP2 NHP2 ribonucleoprotein
NOP10 NOP10 ribonucleoprotein
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NSD1 nuclear receptor binding SET domain protein 1
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
NUP214 nucleoporin 214kDa
PALB2 partner and localizer of BRCA2
PBX1 pre-B-cell leukemia homeobox 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PICALM phosphatidylinositol binding clathrin assembly protein
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNP purine nucleoside phosphorylase
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
PRF1 perforin 1 (pore forming protein)
PRKCD protein kinase C, delta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAD51C RAD51 paralog C
RAD54B RAD54 homolog B (S. cerevisiae)
RAD54L RAD54-like (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RARA retinoic acid receptor, alpha
RB1 retinoblastoma 1
RECQL4 RecQ protein-like 4
RMRP RNA component of mitochondrial RNA processing endoribonuclease
RPL11 ribosomal protein L11
RPL15 ribosomal protein L15
RPL26 ribosomal protein L26
RPL35A ribosomal protein L35a
RPL5 ribosomal protein L5
RPS10 ribosomal protein S10
RPS14 ribosomal protein S14
RPS17 ribosomal protein S17
RPS19 ribosomal protein S19
RPS24 ribosomal protein S24
RPS26 ribosomal protein S26
RPS29 ribosomal protein S29
RPS7 ribosomal protein S7
RTEL1 regulator of telomere elongation helicase 1
RUNX1 runt-related transcription factor 1
SBDS Shwachman-Bodian-Diamond syndrome
SCN9A sodium channel, voltage gated, type IX alpha subunit
SF3B1 splicing factor 3b, subunit 1, 155kDa
SH2B3 SH2B adaptor protein 3
SH2D1A SH2 domain containing 1A
SH3GL1 SH3-domain GRB2-like 1
SLX4 SLX4 structure-specific endonuclease subunit
SRP72 signal recognition particle 72kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STS steroid sulfatase (microsomal), isozyme S
TAL1 T-cell acute lymphocytic leukemia 1
TCL1A T-cell leukemia/lymphoma 1A
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TET2 tet methylcytosine dioxygenase 2
THPO thrombopoietin
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLX1 T-cell leukemia homeobox 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TP53 tumor protein p53
TP63 tumor protein p63
TREM2 triggering receptor expressed on myeloid cells 2
TYROBP TYRO protein tyrosine kinase binding protein
USB1 U6 snRNA biogenesis 1
WAS Wiskott-Aldrich syndrome
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WIPF1 WAS/WASL interacting protein family, member 1
WRAP53 WD repeat containing, antisense to TP53
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase