helveticoside-6047 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the helveticoside-6047 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRL3 adhesion G protein-coupled receptor L3
ADM adrenomedullin
AKAP8L A kinase (PRKA) anchor protein 8-like
AKAP9 A kinase (PRKA) anchor protein 9
ATF3 activating transcription factor 3
AVPI1 arginine vasopressin-induced 1
BAIAP2 BAI1-associated protein 2
BCL6 B-cell CLL/lymphoma 6
BTG1 B-cell translocation gene 1, anti-proliferative
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CCL19 chemokine (C-C motif) ligand 19
CLDN1 claudin 1
CLK1 CDC-like kinase 1
CLK4 CDC-like kinase 4
CTGF connective tissue growth factor
CTTN cortactin
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DLX2 distal-less homeobox 2
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
EDN1 endothelin 1
EED embryonic ectoderm development
EFNA1 ephrin-A1
EFNB2 ephrin-B2
EGR1 early growth response 1
EPHA2 EPH receptor A2
EWSR1 EWS RNA-binding protein 1
FAM46A family with sequence similarity 46, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
GEM GTP binding protein overexpressed in skeletal muscle
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBP1 HMG-box transcription factor 1
HCFC2 host cell factor C2
HES1 hes family bHLH transcription factor 1
HIST1H1T histone cluster 1, H1t
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXC13 homeobox C13
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IL6 interleukin 6
IP6K2 inositol hexakisphosphate kinase 2
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
KLF10 Kruppel-like factor 10
KLF6 Kruppel-like factor 6
KLHL20 kelch-like family member 20
KLHL24 kelch-like family member 24
KLHL25 kelch-like family member 25
LDLR low density lipoprotein receptor
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MED25 mediator complex subunit 25
NACA nascent polypeptide-associated complex alpha subunit
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A2 nuclear receptor subfamily 4, group A, member 2
OVOL1 ovo-like zinc finger 1
PCDH9 protocadherin 9
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PNRC1 proline-rich nuclear receptor coactivator 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RARG retinoic acid receptor, gamma
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RGS16 regulator of G-protein signaling 16
RHOBTB3 Rho-related BTB domain containing 3
RNF24 ring finger protein 24
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS4Y1 ribosomal protein S4, Y-linked 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERTAD3 SERTA domain containing 3
SGPP1 sphingosine-1-phosphate phosphatase 1
SH2D3A SH2 domain containing 3A
SIK1 salt-inducible kinase 1
SKIL SKI-like proto-oncogene
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC38A2 solute carrier family 38, member 2
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SPEN spen family transcriptional repressor
SPRY4 sprouty homolog 4 (Drosophila)
STK17B serine/threonine kinase 17b
STK24 serine/threonine kinase 24
STX3 syntaxin 3
TCF25 transcription factor 25 (basic helix-loop-helix)
TRO trophinin
TTLL5 tubulin tyrosine ligase-like family member 5
TXNIP thioredoxin interacting protein
UBE2H ubiquitin-conjugating enzyme E2H
ZBTB40 zinc finger and BTB domain containing 40
ZBTB43 zinc finger and BTB domain containing 43
ZC3H11A zinc finger CCCH-type containing 11A
ZFAND6 zinc finger, AN1-type domain 6
ZMYM2 zinc finger, MYM-type 2
ZNF750 zinc finger protein 750
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ADAT1 adenosine deaminase, tRNA-specific 1
ALAS1 5'-aminolevulinate synthase 1
ANKRD46 ankyrin repeat domain 46
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARMCX1 armadillo repeat containing, X-linked 1
ASB13 ankyrin repeat and SOCS box containing 13
BATF basic leucine zipper transcription factor, ATF-like
BBX bobby sox homolog (Drosophila)
BMP4 bone morphogenetic protein 4
C11ORF57 chromosome 11 open reading frame 57
CAMTA1 calmodulin binding transcription activator 1
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CCDC15 coiled-coil domain containing 15
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CORO2A coronin, actin binding protein, 2A
CSK c-src tyrosine kinase
CSRNP2 cysteine-serine-rich nuclear protein 2
DET1 de-etiolated homolog 1 (Arabidopsis)
DNAAF2 dynein, axonemal, assembly factor 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETAA1 Ewing tumor-associated antigen 1
FADD Fas (TNFRSF6)-associated via death domain
FAM178A family with sequence similarity 178, member A
FAM86B1 family with sequence similarity 86, member B1
FAM86C1 family with sequence similarity 86, member C1
FAN1 FANCD2/FANCI-associated nuclease 1
FANCF Fanconi anemia, complementation group F
GPR19 G protein-coupled receptor 19
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
HPS4 Hermansky-Pudlak syndrome 4
HPS6 Hermansky-Pudlak syndrome 6
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
IFRD1 interferon-related developmental regulator 1
INO80D INO80 complex subunit D
JRKL JRK-like
KIAA0125 KIAA0125
KIZ kizuna centrosomal protein
KRCC1 lysine-rich coiled-coil 1
LOC100287590 uncharacterized LOC100287590
LOC730101 uncharacterized LOC730101
MAP6D1 MAP6 domain containing 1
MKKS McKusick-Kaufman syndrome
MPPED2 metallophosphoesterase domain containing 2
MXD3 MAX dimerization protein 3
NOL12 nucleolar protein 12
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
ORC3 origin recognition complex, subunit 3
OXSM 3-oxoacyl-ACP synthase, mitochondrial
PAAF1 proteasomal ATPase-associated factor 1
PALB2 partner and localizer of BRCA2
PCF11 PCF11 cleavage and polyadenylation factor subunit
POLI polymerase (DNA directed) iota
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PRR3 proline rich 3
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RHOBTB1 Rho-related BTB domain containing 1
RIBC2 RIB43A domain with coiled-coils 2
RPP40 ribonuclease P/MRP 40kDa subunit
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RSAD1 radical S-adenosyl methionine domain containing 1
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SYBU syntabulin (syntaxin-interacting)
TBC1D16 TBC1 domain family, member 16
TBC1D22A TBC1 domain family, member 22A
TBC1D31 TBC1 domain family, member 31
TBCCD1 TBCC domain containing 1
TFB1M transcription factor B1, mitochondrial
THAP7 THAP domain containing 7
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TRAPPC13 trafficking protein particle complex 13
TRIM27 tripartite motif containing 27
TRIM45 tripartite motif containing 45
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TTC30A tetratricopeptide repeat domain 30A
WDR3 WD repeat domain 3
XBP1 X-box binding protein 1
ZBED8 zinc finger, BED-type containing 8
ZBTB24 zinc finger and BTB domain containing 24
ZBTB3 zinc finger and BTB domain containing 3
ZC3H4 zinc finger CCCH-type containing 4
ZFP30 ZFP30 zinc finger protein
ZIC1 Zic family member 1
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF23 zinc finger protein 23
ZNF239 zinc finger protein 239
ZNF248 zinc finger protein 248
ZNF250 zinc finger protein 250
ZNF302 zinc finger protein 302
ZNF365 zinc finger protein 365
ZNF532 zinc finger protein 532
ZXDC ZXD family zinc finger C