helveticoside-3945 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the helveticoside-3945 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ADM adrenomedullin
AMOTL2 angiomotin like 2
APOE apolipoprotein E
ARTN artemin
ATF3 activating transcription factor 3
ATF7IP activating transcription factor 7 interacting protein
AVPI1 arginine vasopressin-induced 1
BCL6 B-cell CLL/lymphoma 6
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CDK19 cyclin-dependent kinase 19
CGA glycoprotein hormones, alpha polypeptide
CLDN1 claudin 1
CLK1 CDC-like kinase 1
CLK4 CDC-like kinase 4
CTGF connective tissue growth factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DCP1A decapping mRNA 1A
DLX2 distal-less homeobox 2
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
EDN1 endothelin 1
EED embryonic ectoderm development
EFNA1 ephrin-A1
EGR1 early growth response 1
EPHA2 EPH receptor A2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERCC6 excision repair cross-complementation group 6
FLCN folliculin
FOS FBJ murine osteosarcoma viral oncogene homolog
GEM GTP binding protein overexpressed in skeletal muscle
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRB7 growth factor receptor-bound protein 7
HBP1 HMG-box transcription factor 1
HIST1H1T histone cluster 1, H1t
HIST1H2BG histone cluster 1, H2bg
HOXA10 homeobox A10
HOXC13 homeobox C13
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDI2-AS1 IDI2 antisense RNA 1
IER2 immediate early response 2
IL6 interleukin 6
IP6K2 inositol hexakisphosphate kinase 2
JAM2 junctional adhesion molecule 2
JUN jun proto-oncogene
KLF10 Kruppel-like factor 10
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
LINS lines homolog (Drosophila)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MCL1 myeloid cell leukemia 1
MIER2 mesoderm induction early response 1, family member 2
MXD1 MAX dimerization protein 1
N4BP2L2 NEDD4 binding protein 2-like 2
NACA nascent polypeptide-associated complex alpha subunit
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OVOL1 ovo-like zinc finger 1
OVOL2 ovo-like zinc finger 2
PDLIM3 PDZ and LIM domain 3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RGS16 regulator of G-protein signaling 16
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCNN1B sodium channel, non voltage gated 1 beta subunit
SERTAD3 SERTA domain containing 3
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SKIL SKI-like proto-oncogene
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC45A2 solute carrier family 45, member 2
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPRY4 sprouty homolog 4 (Drosophila)
STAB2 stabilin 2
STX3 syntaxin 3
TCF25 transcription factor 25 (basic helix-loop-helix)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
THAP3 THAP domain containing, apoptosis associated protein 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TPP1 tripeptidyl peptidase I
TXNIP thioredoxin interacting protein
UBE2H ubiquitin-conjugating enzyme E2H
VCL vinculin
YTHDC1 YTH domain containing 1
ZBTB43 zinc finger and BTB domain containing 43
ZMYM5 zinc finger, MYM-type 5
ZNF292 zinc finger protein 292
ZNF335 zinc finger protein 335
ZNF430 zinc finger protein 430
ZNF654 zinc finger protein 654
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
ADAT1 adenosine deaminase, tRNA-specific 1
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD46 ankyrin repeat domain 46
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARMCX1 armadillo repeat containing, X-linked 1
ASB13 ankyrin repeat and SOCS box containing 13
BBX bobby sox homolog (Drosophila)
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
CAMKMT calmodulin-lysine N-methyltransferase
CANT1 calcium activated nucleotidase 1
CBR3 carbonyl reductase 3
CCP110 centriolar coiled coil protein 110kDa
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CORT cortistatin
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DET1 de-etiolated homolog 1 (Arabidopsis)
ECHDC3 enoyl CoA hydratase domain containing 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
FADD Fas (TNFRSF6)-associated via death domain
FAM86B1 family with sequence similarity 86, member B1
FANCF Fanconi anemia, complementation group F
FPGT fucose-1-phosphate guanylyltransferase
GEMIN4 gem (nuclear organelle) associated protein 4
GEMIN6 gem (nuclear organelle) associated protein 6
HPS6 Hermansky-Pudlak syndrome 6
HSPA1L heat shock 70kDa protein 1-like
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IMPACT impact RWD domain protein
IPP intracisternal A particle-promoted polypeptide
IRAK4 interleukin-1 receptor-associated kinase 4
IRF6 interferon regulatory factor 6
ITPKB inositol-trisphosphate 3-kinase B
KIAA0125 KIAA0125
KIZ kizuna centrosomal protein
KRCC1 lysine-rich coiled-coil 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC730101 uncharacterized LOC730101
MAT2A methionine adenosyltransferase II, alpha
MKKS McKusick-Kaufman syndrome
NAV2 neuron navigator 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NOD1 nucleotide-binding oligomerization domain containing 1
ORC3 origin recognition complex, subunit 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PAAF1 proteasomal ATPase-associated factor 1
PAGR1 PAXIP1 associated glutamate-rich protein 1
PALB2 partner and localizer of BRCA2
PARP16 poly (ADP-ribose) polymerase family, member 16
PCF11 PCF11 cleavage and polyadenylation factor subunit
PDCD5 programmed cell death 5
PER3 period circadian clock 3
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
POGK pogo transposable element with KRAB domain
POLI polymerase (DNA directed) iota
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRR3 proline rich 3
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RFTN1 raftlin, lipid raft linker 1
RHOBTB1 Rho-related BTB domain containing 1
RNF31 ring finger protein 31
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPP40 ribonuclease P/MRP 40kDa subunit
RSAD1 radical S-adenosyl methionine domain containing 1
RUFY2 RUN and FYVE domain containing 2
S100PBP S100P binding protein
SACS sacsin molecular chaperone
SCRN3 secernin 3
SH2D4A SH2 domain containing 4A
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SRD5A3 steroid 5 alpha-reductase 3
TBC1D16 TBC1 domain family, member 16
TBC1D31 TBC1 domain family, member 31
TBCCD1 TBCC domain containing 1
TFB1M transcription factor B1, mitochondrial
THAP7 THAP domain containing 7
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THYN1 thymocyte nuclear protein 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIM45 tripartite motif containing 45
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TSEN2 TSEN2 tRNA splicing endonuclease subunit
WDR3 WD repeat domain 3
XBP1 X-box binding protein 1
ZBED8 zinc finger, BED-type containing 8
ZBTB24 zinc finger and BTB domain containing 24
ZC3H4 zinc finger CCCH-type containing 4
ZFP69B ZFP69 zinc finger protein B
ZNF23 zinc finger protein 23
ZNF239 zinc finger protein 239
ZNF248 zinc finger protein 248
ZNF623 zinc finger protein 623
ZNF813 zinc finger protein 813