helveticoside-3770 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the helveticoside-3770 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADM adrenomedullin
AFF4 AF4/FMR2 family, member 4
ANGPTL4 angiopoietin-like 4
ARC activity-regulated cytoskeleton-associated protein
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL14 ADP-ribosylation factor-like 14
ATF3 activating transcription factor 3
BCL6 B-cell CLL/lymphoma 6
BDNF brain-derived neurotrophic factor
BTG2 BTG family, member 2
CCNL1 cyclin L1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2AIP CDKN2A interacting protein
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCF1 cardiotrophin-like cytokine factor 1
CLDN1 claudin 1
CLK1 CDC-like kinase 1
CREB5 cAMP responsive element binding protein 5
CTGF connective tissue growth factor
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT3 DNA-damage-inducible transcript 3
DLX2 distal-less homeobox 2
DMBT1 deleted in malignant brain tumors 1
DUSP1 dual specificity phosphatase 1
EDN1 endothelin 1
EGR1 early growth response 1
EGR3 early growth response 3
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM46C family with sequence similarity 46, member C
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL2 FOS-like antigen 2
FRMD4B FERM domain containing 4B
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
GHRHR growth hormone releasing hormone receptor
GPR87 G protein-coupled receptor 87
HBEGF heparin-binding EGF-like growth factor
HIST1H1T histone cluster 1, H1t
HIST1H2AE histone cluster 1, H2ae
HIST1H2BG histone cluster 1, H2bg
HIST1H3A histone cluster 1, H3a
HIST1H4D histone cluster 1, H4d
HIST1H4E histone cluster 1, H4e
HIST2H2BE histone cluster 2, H2be
HIST3H2A histone cluster 3, H2a
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL11 interleukin 11
IL1RL1 interleukin 1 receptor-like 1
IL6 interleukin 6
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KLHL25 kelch-like family member 25
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAK male germ cell-associated kinase
MYLIP myosin regulatory light chain interacting protein
NR4A2 nuclear receptor subfamily 4, group A, member 2
PELI1 pellino E3 ubiquitin protein ligase 1
PER2 period circadian clock 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB30 RAB30, member RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RGS16 regulator of G-protein signaling 16
RHOB ras homolog family member B
RND1 Rho family GTPase 1
RNMT RNA (guanine-7-) methyltransferase
SAT1 spermidine/spermine N1-acetyltransferase 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNAI1 snail family zinc finger 1
SRSF5 serine/arginine-rich splicing factor 5
STC2 stanniocalcin 2
STX3 syntaxin 3
SWAP70 SWAP switching B-cell complex 70kDa subunit
TEX14 testis expressed 14
TGFB2 transforming growth factor, beta 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOB2 transducer of ERBB2, 2
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
UGCG UDP-glucose ceramide glucosyltransferase
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGAP22 Rho GTPase activating protein 22
ARMCX2 armadillo repeat containing, X-linked 2
ASB13 ankyrin repeat and SOCS box containing 13
ATP10D ATPase, class V, type 10D
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BHLHE41 basic helix-loop-helix family, member e41
C14ORF169 chromosome 14 open reading frame 169
C16ORF59 chromosome 16 open reading frame 59
C2ORF68 chromosome 2 open reading frame 68
C4ORF29 chromosome 4 open reading frame 29
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBR3 carbonyl reductase 3
CDC7 cell division cycle 7
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CPT2 carnitine palmitoyltransferase 2
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DENND2D DENN/MADD domain containing 2D
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAAF2 dynein, axonemal, assembly factor 2
EFNB1 ephrin-B1
FADD Fas (TNFRSF6)-associated via death domain
FANCF Fanconi anemia, complementation group F
FBXL7 F-box and leucine-rich repeat protein 7
FHOD1 formin homology 2 domain containing 1
GEMIN6 gem (nuclear organelle) associated protein 6
GLMN glomulin, FKBP associated protein
GLT8D1 glycosyltransferase 8 domain containing 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GOLGA5 golgin A5
GPR19 G protein-coupled receptor 19
GRAMD4 GRAM domain containing 4
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HOXA11 homeobox A11
HOXC10 homeobox C10
HPS4 Hermansky-Pudlak syndrome 4
HPS6 Hermansky-Pudlak syndrome 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
ITGA10 integrin, alpha 10
ITPKB inositol-trisphosphate 3-kinase B
JRKL JRK-like
KIAA1107 KIAA1107
KRCC1 lysine-rich coiled-coil 1
LINC00339 long intergenic non-protein coding RNA 339
LYPD3 LY6/PLAUR domain containing 3
MAGEH1 melanoma antigen family H1
MAP6D1 MAP6 domain containing 1
MED31 mediator complex subunit 31
MKS1 Meckel syndrome, type 1
MLYCD malonyl-CoA decarboxylase
NAT6 N-acetyltransferase 6 (GCN5-related)
NME5 NME/NM23 family member 5
NOD1 nucleotide-binding oligomerization domain containing 1
NTSR1 neurotensin receptor 1 (high affinity)
PALMD palmdelphin
PAQR5 progestin and adipoQ receptor family member V
PCOLCE procollagen C-endopeptidase enhancer
PLXNB3 plexin B3
PPP1R3D protein phosphatase 1, regulatory subunit 3D
RAB3A RAB3A, member RAS oncogene family
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RHOBTB1 Rho-related BTB domain containing 1
RHOBTB2 Rho-related BTB domain containing 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPGRIP1L RPGRIP1-like
RSAD1 radical S-adenosyl methionine domain containing 1
RWDD2A RWD domain containing 2A
SAMD9 sterile alpha motif domain containing 9
SCO2 SCO2 cytochrome c oxidase assembly protein
SEPHS2 selenophosphate synthetase 2
SETD6 SET domain containing 6
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLITRK5 SLIT and NTRK-like family, member 5
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBCCD1 TBCC domain containing 1
TENM4 teneurin transmembrane protein 4
TRIM52 tripartite motif containing 52
TRIM66 tripartite motif containing 66
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSC22D4 TSC22 domain family, member 4
TTC30A tetratricopeptide repeat domain 30A
WDR25 WD repeat domain 25
ZBED8 zinc finger, BED-type containing 8
ZNF140 zinc finger protein 140
ZNF205 zinc finger protein 205
ZNF239 zinc finger protein 239
ZNF32 zinc finger protein 32
ZNF365 zinc finger protein 365
ZNF668 zinc finger protein 668
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862