heart conduction disease Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A cardiovascular system disease that involves the heart's electrical conduction system. (Human Disease Ontology, DOID_10273)
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Genes

87 genes associated with the disease heart conduction disease in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SCN10A sodium channel, voltage gated, type X alpha subunit 2.31033
SLC35F1 solute carrier family 35, member F1 1.54448
TBX5 T-box 5 1.33613
NFIA nuclear factor I/A 1.25426
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 1.2206
RNF207 ring finger protein 207 1.17894
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1.09588
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.07383
ZFHX3 zinc finger homeobox 3 1.07383
SCN5A sodium channel, voltage gated, type V alpha subunit 1.02486
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 1.00628
PRRX1 paired related homeobox 1 0.971299
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.971299
LINC00477 long intergenic non-protein coding RNA 477 0.932337
SYNE2 spectrin repeat containing, nuclear envelope 2 0.910378
CREBRF CREB3 regulatory factor 0.897589
CAV1 caveolin 1, caveolae protein, 22kDa 0.850113
LIG3 ligase III, DNA, ATP-dependent 0.835734
MEIS1 Meis homeobox 1 0.817078
ITGA9 integrin, alpha 9 0.7623
C9ORF3 chromosome 9 open reading frame 3 0.7623
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.728541
OLFML2B olfactomedin-like 2B 0.69843
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.682635
C1ORF226 chromosome 1 open reading frame 226 0.63207
ARHGAP24 Rho GTPase activating protein 24 0.58494
SYNPO2L synaptopodin 2-like 0.572184
SULF2 sulfatase 2 0.52461
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 0.486425
WNT11 wingless-type MMTV integration site family, member 11 0.464771
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 0.449873
ADGRD1 adhesion G protein-coupled receptor D1 0.449873
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.438544
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.4215
DPT dermatopontin 0.368757
CXCR4 chemokine (C-X-C motif) receptor 4 0.345945
TEKT3 tektin 3 0.345945
WNT8A wingless-type MMTV integration site family, member 8A 0.345945
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding) 0.311576
TMEM44 transmembrane protein 44 0.285417
ARHGAP10 Rho GTPase activating protein 10 0.285417
FAS Fas cell surface death receptor 0.285417
PTPRG protein tyrosine phosphatase, receptor type, G 0.274608
CNOT1 CCR4-NOT transcription complex, subunit 1 0.256228
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 0.256228
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.256228
FRMD4A FERM domain containing 4A 0.256228
GALR1 galanin receptor 1 0.256228
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.256228
HLA-DPB2 major histocompatibility complex, class II, DP beta 2 (pseudogene) 0.256228
PARP15 poly (ADP-ribose) polymerase family, member 15 0.256228
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.197766
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.197766
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.197766
ELMO1 engulfment and cell motility 1 0.197766
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 0.197766
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.197766
CEP85L centrosomal protein 85kDa-like 0.197766
IL5RA interleukin 5 receptor, alpha 0.197766
TEX43 testis expressed 43 0.197766
CLDN15 claudin 15 0.197766
COL8A1 collagen, type VIII, alpha 1 0.197766
TTN titin 0.197766
OSBPL6 oxysterol binding protein-like 6 0.15771
STK32B serine/threonine kinase 32B 0.15771
ARHGAP25 Rho GTPase activating protein 25 0.126165
XYLB xylulokinase homolog (H. influenzae) 0.126165
PDZRN3 PDZ domain containing ring finger 3 0.126165
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 0.100789
SFRP2 secreted frizzled-related protein 2 0.100789
CLDN14 claudin 14 0.100789
FAM189A1 family with sequence similarity 189, member A1 0.100789
BMPR1B bone morphogenetic protein receptor, type IB 0.080593
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.080593
IRF2BP2 interferon regulatory factor 2 binding protein 2 0.080593
FOXP1 forkhead box P1 0.080593
AGA aspartylglucosaminidase 0.064973
NUDT12 nudix (nucleoside diphosphate linked moiety X)-type motif 12 0.064973
DCLK1 doublecortin-like kinase 1 0.052255
PARM1 prostate androgen-regulated mucin-like protein 1 0.052255
FGF14 fibroblast growth factor 14 0.052255
PRKCE protein kinase C, epsilon 0.052255
RASL11A RAS-like, family 11, member A 0.052255
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 0.052255
MBP myelin basic protein 0.043246
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 0.043246
RPS17P5 ribosomal protein S17 pseudogene 5 0.043246